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A new tool to study genetic expression using 2-D electrophoresis data: the functional map concept

Abstract : A method derived from general computerized data analysis techniques is used here first to tabulate the characteristics of individual peptide spots observed by two-dimensional electrophoresis and to compare these characteristics among spots. Multivariate analysis of such data arrays then leads to the grouping of spots in an n-dimensional space, according to their expression characteristics. Such maps display zones which are characteristic of the tissue studied. These functional maps provide a powerful analytical tool for describing such functional interactions and also for predicting the function of unidentified peptides observed on the electrophoresis gels.
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https://hal.archives-ouvertes.fr/hal-03739131
Contributor : Thierry Rabilloud Connect in order to contact the contributor
Submitted on : Friday, July 29, 2022 - 10:32:13 AM
Last modification on : Wednesday, August 3, 2022 - 3:42:00 AM

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FEBS Letters - September 23 19...
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Thierry Rabilloud, Pierre Vincens, Philippe Tarroux. A new tool to study genetic expression using 2-D electrophoresis data: the functional map concept. FEBS Letters, Wiley, 1985, 189 (2), pp.171-178. ⟨10.1016/0014-5793(85)81018-8⟩. ⟨hal-03739131⟩

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