SARS-CoV-2 antibody seroprevalence follow-up in Malagasy blood donors during the 2020 COVID-19 Epidemic - Institut Pasteur de Madagascar Accéder directement au contenu
Article Dans Une Revue EBioMedicine Année : 2021

SARS-CoV-2 antibody seroprevalence follow-up in Malagasy blood donors during the 2020 COVID-19 Epidemic

Philippe Dussart
Jean-Michel Heraud
Soa Fy Andriamandimby

Résumé

Background: The incidence of the 2020 COVID-19 epidemic in Africa seems to be different from that of the rest of the world, however its true extent is probably underestimated. Conducting population based sero-surveys during the epidemic has moreover been extremely challenging, driving our group and others to study blood donor samples. Methods: We collected regional epidemiological COVID-19 surveillance data, and simultaneously monitored anti-SARS-CoV-2 antibody seroprevalences monthly throughout the epidemic in 5 major Region-associated Blood Transfusion Centres of Madagascar over a period of 9 months. Findings: Soon after attaining the first epidemic peaks between May and August 2020, both crude and population-weighted test-performance-adjusted seroprevalences of anti-SARS-CoV-2 antibodies was in Malagasy blood donors rapidly increased up to over 40% positivity. Interpretation: These findings suggest a high cumulative incidence of infection and seroconversion, which may have contributed to the observed deceleration of infection rates, but was not sufficient to prevent the second epidemic wave that struck Madagascar in Spring 2021.
Fichier principal
Vignette du fichier
1-s2.0-S2352396421002127-main.pdf (816.03 Ko) Télécharger le fichier
Origine : Publication financée par une institution

Dates et versions

pasteur-03254611 , version 1 (09-06-2021)

Licence

Paternité - Pas d'utilisation commerciale - Pas de modification

Identifiants

Citer

Matthieu Schoenhals, Niry Rabenindrina, Jean Marius Rakotondramanga, Philippe Dussart, Rindra Randremanana, et al.. SARS-CoV-2 antibody seroprevalence follow-up in Malagasy blood donors during the 2020 COVID-19 Epidemic. EBioMedicine, 2021, 68, pp.103419. ⟨10.1016/j.ebiom.2021.103419⟩. ⟨pasteur-03254611⟩
79 Consultations
66 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More