Collective Domino Approach toward the Core of Molecules Isolated from the Genus Schisandra

Alexandra Bartoli (1) , Gaëlle Chouraqui (2) , Jean-Luc Parrain (2)

1 ISM2 - Institut des Sciences Moléculaires de Marseille
2 STeRéO

A concise route to the ABC and ABCD core of molecules isolated from the genus Schisandra has been accomplished. The synthesis demonstrated high atom efficiency employing a new one-pot cascade which sequentially built three rings and a quaternary spirocenter.

Mots clés: quaternary center; Schisandra genus; spirocenter; alkylidene butenolide

Domaines: Chimie organique

Alexandra Bartoli, Gaëlle Chouraqui, Jean-Luc Parrain. Collective Domino Approach toward the Core of Molecules Isolated from the Genus Schisandra. Organic Letters, 2012, 14 (1), pp.122-125. ⟨10.1021/ol2029146⟩. ⟨hal-00676888⟩