Microwave-Assisted Wolff Rearrangement of Cyclic 2-Diazo-1,3-Diketones: An Eco-compatible Route to alpha-Carbonylated Cycloalkanones
Résumé
The microwave-assisted Wolff rearrangement of cyclic 2-diazo-1,3-diketones performed in the presence of a stoichiometric amount of alcohol, amine, or thiol is an efficient, user, and environmentally friendly synthetic protocol for the synthesis of alpha-carbonylated cycloalkanones. This approach proves superior to existing protocols in scope and eco-compatibility.