First Total Synthesis and Assignment of the Stereochemistry of Crispatenine

Julien Bourdron (1) , Laurent Commeiras (1) , Gérard Audran (1) , Nicolas Vanthuyne (2) , Jean-Claude Hubaud , Jean-Luc Parrain (1)

1 STeRéO
2 ChiroSciences

The first racemic and enantioselective synthesis of crispatenine 1 has been achieved, which involved a few steps, enabling the assignment of the absolute and relative configurations

Mots clés: Natural product; Total synthesis; Caulerpa; terpenoids

Domaines: Chimie organique

Julien Bourdron, Laurent Commeiras, Gérard Audran, Nicolas Vanthuyne, Jean-Claude Hubaud, et al.. First Total Synthesis and Assignment of the Stereochemistry of Crispatenine. Journal of Organic Chemistry, 2007, 72, pp.3770-3775. ⟨10.1021/jo070045j⟩. ⟨hal-00678959⟩