Welcome to pandoraviruses at the 'Fourth TRUC' club

Abstract : Nucleocytoplasmic large DNA viruses, or representatives of the proposed order Megavirales, belong to families of giant viruses that infect a broad range of eukaryotic hosts. Megaviruses have been previously described to comprise a fourth monophylogenetic TRUC (things resisting uncompleted classification) together with cellular domains in the universal tree of life. Recently described pandoraviruses have large (1.9-2.5 MB) and highly divergent genomes. In the present study, we updated the classification of pandoraviruses and other reported giant viruses. Phylogenetic trees were constructed based on six informational genes. Hierarchical clustering was performed based on a set of informational genes from Megavirales members and cellular organisms. Homologous sequences were selected from cellular organisms using TimeTree software, comprising comprehensive, and representative sets of members from Bacteria, Archaea, and Eukarya. Phylogenetic analyses based on three conserved core genes clustered pandoraviruses with phycodnaviruses, exhibiting their close relatedness. Additionally, hierarchical clustering analyses based on informational genes grouped pandoraviruses with Megavirales members as a super group distinct from cellular organisms. Thus, the analyses based on core conserved genes revealed that pandoraviruses are new genuine members of the 'Fourth TRUC' club, encompassing distinct life forms compared with cellular organisms.
Type de document :
Article dans une revue
Frontiers in microbiology, Frontiers Research Foundation, 2015, 6 (423), <10.3389/fmicb.2015.00423>
Liste complète des métadonnées

https://hal-amu.archives-ouvertes.fr/hal-01211489
Contributeur : Administrateur Hal Amu <>
Soumis le : lundi 5 octobre 2015 - 11:28:05
Dernière modification le : mercredi 7 octobre 2015 - 14:59:04
Document(s) archivé(s) le : mercredi 6 janvier 2016 - 10:34:09

Fichier

ptpmcrender.pdf
Fichiers éditeurs autorisés sur une archive ouverte

Identifiants

Collections

Citation

Vikas Sharma, Philippe Colson, Olivier Chabrol, Patrick Scheid, Pierre Pontarotti, et al.. Welcome to pandoraviruses at the 'Fourth TRUC' club. Frontiers in microbiology, Frontiers Research Foundation, 2015, 6 (423), <10.3389/fmicb.2015.00423>. <hal-01211489>

Partager

Métriques

Consultations de
la notice

149

Téléchargements du document

57