In vivo labeling with 2H2O reveals a human neutrophil lifespan of 5.4 days, Blood, vol.116, issue.4, pp.625-632, 2010. ,
DOI : 10.1182/blood-2010-01-259028
Programmed cell death of the normal human neutrophil: An in vitro model of senescence, Microscopy Research and Technique, vol.82, issue.4, pp.327-371, 1994. ,
DOI : 10.1002/jemt.1070280408
Phagocytosis of Apoptotic Neutrophils Regulates Granulopoiesis via IL-23 and IL-17, Immunity, vol.22, issue.3, pp.285-94, 2005. ,
DOI : 10.1016/j.immuni.2005.01.011
Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages., Journal of Clinical Investigation, vol.83, issue.3, pp.865-75, 1989. ,
DOI : 10.1172/JCI113970
How human neutrophils kill and degrade microbes: an integrated view, Immunological Reviews, vol.175, issue.1, pp.88-102, 2007. ,
DOI : 10.1073/pnas.0337370100
Approaching the Asymptote? Evolution and Revolution in Immunology, Cold Spring Harbor Symposia on Quantitative Biology, vol.54, issue.0, pp.1-13, 1989. ,
DOI : 10.1101/SQB.1989.054.01.003
Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation, Science, vol.330, issue.6002, pp.362-368, 2010. ,
DOI : 10.1126/science.1195491
NEUTROPHIL APOPTOSIS IN INFECTIOUS DISEASE, Experimental Lung Research, vol.66, issue.1, pp.519-547, 2007. ,
DOI : 10.4049/jimmunol.169.2.898
Modulation of phagocyte apoptosis by bacterial pathogens, Apoptosis, vol.9, issue.4, pp.399-413, 2004. ,
DOI : 10.1023/B:APPT.0000031448.64969.fa
Clearance of apoptotic cells: implications in health and disease, The Journal of Cell Biology, vol.163, issue.7, pp.1059-70, 2010. ,
DOI : 10.1016/j.cell.2008.01.033
Induction of Necrosis in Human Neutrophils by Shigella flexneri Requires Type III Secretion, IpaB and IpaC Invasins, and Actin Polymerization, Infection and Immunity, vol.68, issue.3, pp.1289-96, 2000. ,
DOI : 10.1128/IAI.68.3.1289-1296.2000
Induction of Neutrophil Apoptosis by the Pseudomonas aeruginosa Exotoxin Pyocyanin: A Potential Mechanism of Persistent Infection, The Journal of Immunology, vol.168, issue.4, pp.1861-1869, 2002. ,
DOI : 10.4049/jimmunol.168.4.1861
Pseudomonas aeruginosa Cystic Fibrosis Isolates Induce Rapid, Type III Secretion-Dependent, but ExoU-Independent, Oncosis of Macrophages and Polymorphonuclear Neutrophils, Infection and Immunity, vol.68, issue.5, pp.2916-2940, 2000. ,
DOI : 10.1128/IAI.68.5.2916-2924.2000
Anaplasma phagocytophilum Reduces Neutrophil Apoptosis In Vivo, Infection and Immunity, vol.71, issue.4, pp.1995-2001, 2003. ,
DOI : 10.1128/IAI.71.4.1995-2001.2003
Chlamydia pneumoniae Multiply in Neutrophil Granulocytes and Delay Their Spontaneous Apoptosis, The Journal of Immunology, vol.172, issue.3, pp.1768-1776, 2004. ,
DOI : 10.4049/jimmunol.172.3.1768
Brucella abortus Uses a Stealthy Strategy to Avoid Activation of the Innate Immune System during the Onset of Infection, PLoS ONE, vol.178, issue.178, pp.631-17637846, 2007. ,
DOI : 10.1371/journal.pone.0000631.t001
An evolutionary strategy for a stealthy intracellular Brucella pathogen, Immunological Reviews, vol.38, issue.1, pp.211-245, 2011. ,
DOI : 10.1111/j.1600-065X.2010.00982.x
URL : https://hal.archives-ouvertes.fr/hal-00609655
The Differential Interaction of Brucella and Ochrobactrum with Innate Immunity Reveals Traits Related to the Evolution of Stealthy Pathogens, PLoS ONE, vol.4, issue.6, 2009. ,
DOI : 10.1371/journal.pone.0005893.t001
URL : https://hal.archives-ouvertes.fr/hal-00431866
Neutrophils Exert a Suppressive Effect on Th1 Responses to Intracellular Pathogen Brucella abortus, PLoS Pathogens, vol.142, issue.Pt 4, p.23458832, 2013. ,
DOI : 10.1371/journal.ppat.1003167.s009
Brucella intracellular life: from invasion to intracellular replication, Veterinary Microbiology, vol.90, issue.1-4, pp.281-97, 2002. ,
DOI : 10.1016/S0378-1135(02)00214-6
Survival of the fittest: how Brucella strains adapt to their intracellular niche in the host, Medical Microbiology and Immunology, vol.8, issue.83, pp.221-259, 2009. ,
DOI : 10.1007/s00430-009-0123-8
In Vitro Brucella suis Infection Prevents the Programmed Cell Death of Human Monocytic Cells, Infection and Immunity, vol.68, issue.1, pp.342-51, 2000. ,
DOI : 10.1128/IAI.68.1.342-351.2000
URL : https://hal.archives-ouvertes.fr/hal-00193968
Studies in the Pathology and Pathogenesis of Experimental Brucellosis: II. The Formation of the Hepatic Granuloma and its Evolution, Journal of Infectious Diseases, vol.89, issue.1, pp.87-94, 1951. ,
DOI : 10.1093/infdis/89.1.87
Strain 19, Veterinary Pathology, vol.19, issue.1, pp.28-35, 1988. ,
DOI : 10.1177/030098588802500104
Interaction of polymorphonuclear leukocytes with smooth and rough strains of Brucella abortus, Infect Immun, vol.23, pp.737-779, 1979. ,
The outer membranes of Brucella spp. are resistant to bactericidal cationic peptides, Infect Immun, vol.63, pp.3054-61, 1995. ,
Hematologic Changes in Brucellosis, Journal of Infectious Diseases, vol.150, issue.3, pp.419-443, 1984. ,
DOI : 10.1093/infdis/150.3.419
In Situ Microscopy Analysis Reveals Local Innate Immune Response Developed around Brucella Infected Cells in Resistant and Susceptible Mice, PLoS Pathogens, vol.5, issue.3, p.22479178, 2012. ,
DOI : 10.1371/journal.ppat.1002575.s014
Studies on the leucocyte content of milk drawn from Brucella abortus infected udders, J Bacteriol, vol.27, pp.293-301, 1934. ,
Ingestion and intracellular survival of Brucella abortus in human and bovine polymorphonuclear leukocytes, Infect Immun, vol.46, pp.224-254, 1984. ,
Inhibition of the degranulation and myeloperoxidase activity of human polymorphonuclear neutrophils by Brucella melitensis, Microbiología, vol.7, pp.113-122, 1991. ,
Lysosomal accumulation and recycling of lipopolysaccharide to the cell surface of murine macrophages, an in vitro and in vivo study, J Immunol, vol.162, pp.6784-6791, 1999. ,
Invasion, intracellular trafficking and replication of Brucella organisms in professional and non-professional phagocytes, Brucella: Molecular and Cellular Biology. United Kingdom, pp.287-312, 2004. ,
Brucella abortus Lipopolysaccharide in Murine Peritoneal Macrophages Acts as a Down-Regulator of T Cell Activation, The Journal of Immunology, vol.165, issue.9, pp.5202-5212, 2000. ,
DOI : 10.4049/jimmunol.165.9.5202
Purification of intracellular bacteria: isolation of viable Brucella abortus from host cells. Host-Bacteria Interactions, Methods Protoc, vol.1197, pp.245-60, 2014. ,
Brucellacidal activity of human and bovine polymorphonuclear leukocyte granule extracts against smooth and rough strains of Brucella abortus, Infect Immun, vol.46, pp.231-236, 1984. ,
Brucella Control of Dendritic Cell Maturation Is Dependent on the TIR-Containing Protein Btp1, PLoS Pathogens, vol.61, issue.2, p.18266466, 2008. ,
DOI : 10.1371/journal.ppat.0040021.sg008
URL : https://hal.archives-ouvertes.fr/hal-00294210
Structure of the O-chain of the phenol-phase soluble cellular lipopolysaccharide of Yersinia enterocolitica serotype O:9, European Journal of Biochemistry, vol.51, issue.1, pp.195-200, 1984. ,
DOI : 10.1016/0304-4165(79)90280-0
Antigenic S-type lipopolysaccharide of Brucella abortus 1119?3, Infect Immun, vol.46, pp.384-392, 1984. ,
Role of Lipid A Acylation in Yersinia enterocolitica Virulence, Infection and Immunity, vol.78, issue.6, pp.2768-81, 2010. ,
DOI : 10.1128/IAI.01417-09
Brucella lipopolysaccharide: structure, biosynthesis and genetics, Brucella: Molecular and Cellular Biology Horizon Bioscience, pp.159-191, 2004. ,
The Lipopolysaccharide Core of Brucella abortus Acts as a Shield Against Innate Immunity Recognition, PLoS Pathogens, vol.1329, issue.5, p.22589715, 2012. ,
DOI : 10.1371/journal.ppat.1002675.s011
The study of the core part and non-repeating elements of the O-antigen of Brucella lipopolysaccharide, Carbohydrate Research, vol.366, pp.33-40, 2013. ,
DOI : 10.1016/j.carres.2012.11.004
Brucella abortus and Its Closest Phylogenetic Relative, Ochrobactrum spp., Differ in Outer Membrane Permeability and Cationic Peptide Resistance, Infection and Immunity, vol.68, issue.6, pp.3210-3218, 2000. ,
DOI : 10.1128/IAI.68.6.3210-3218.2000
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC97564
The Role of Toll-Like Receptors in the Regulation of Neutrophil Migration, Activation, and Apoptosis, Clinical Infectious Diseases, vol.41, issue.Supplement 7, pp.421-427, 2005. ,
DOI : 10.1086/431992
CD14 regulates the dendritic cell life cycle after LPS exposure through NFAT activation, Nature, vol.5, issue.7252, pp.264-272, 2009. ,
DOI : 10.1038/nature08118
Effect of Brucella abortus lipopolysaccharide on oxidative metabolism and lysozyme release by human neutrophils, Infect Immun, vol.60, pp.1699-702, 1992. ,
Neutrophil Extracellular Traps Kill Bacteria, Science, vol.303, issue.5663, pp.1532-1537, 2004. ,
DOI : 10.1126/science.1092385
Novel cell death program leads to neutrophil extracellular traps, The Journal of Cell Biology, vol.74, issue.2, pp.231-272, 2007. ,
DOI : 10.1073/pnas.85.22.8531
Peculiarities of cell death mechanisms in neutrophils, Cell Death and Differentiation, vol.62, issue.9, pp.1457-69, 2011. ,
DOI : 10.1074/jbc.M604051200
Characteristics of the inhibition of NADPH oxidase activation in neutrophils by apocynin, a methoxy-substituted catechol., American Journal of Respiratory Cell and Molecular Biology, vol.11, issue.1, pp.95-102, 1994. ,
DOI : 10.1165/ajrcmb.11.1.8018341
Expression of a functional neutrophil-type NADPH oxidase in cultured rat coronary microvascular endothelial cells, Cardiovascular Research, vol.38, issue.1, pp.256-62, 1998. ,
DOI : 10.1016/S0008-6363(98)00003-0
Protection of Human Neutrophils by Endogenous Catalase, Journal of Clinical Investigation, vol.65, issue.6, pp.1515-1537, 1980. ,
DOI : 10.1172/JCI109817
Caspase 3/caspase-activated DNase promote cell differentiation by inducing DNA strand breaks, Proceedings of the National Academy of Sciences, vol.107, issue.9, pp.4230-4235, 2010. ,
DOI : 10.1073/pnas.0913089107
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840077
Caspase-4 and caspase-5, members of the ICE/CED-3 family of cysteine proteases, are CrmA-inhibitable proteases, Cell Death and Differentiation, vol.4, issue.6, pp.473-481, 1997. ,
DOI : 10.1038/sj.cdd.4400268
Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death, Nature Reviews Molecular Cell Biology, vol.3, issue.11, pp.727-763, 2013. ,
DOI : 10.1038/nrm3683
Targeted disruption of caspase genes in mice: What they tell us about the functions of individual caspases in apoptosis, Immunology and Cell Biology, vol.8, issue.1, pp.58-63, 1999. ,
DOI : 10.1093/emboj/17.3.706
Caspase knockouts: matters of life and death, Cell Death and Differentiation, vol.6, issue.11, pp.1043-53, 1999. ,
DOI : 10.1038/sj.cdd.4400593
: Role of Interleukin-8, Scandinavian Journal of Immunology, vol.51, issue.2, pp.73-82, 2009. ,
DOI : 10.1111/j.1365-3083.2008.02199.x
The induction by human interleukin-6 of apoptosis in the promonocytic cell line U937 and human neutrophils, J Biol Chem, vol.267, pp.21612-21618, 1992. ,
Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products, Blood, vol.80, pp.2012-2020, 1992. ,
Autoregulation mechanism of human neutrophil apoptosis during bacterial infection???, Molecular Immunology, vol.45, issue.7, pp.2087-96, 2008. ,
DOI : 10.1016/j.molimm.2007.10.013
Apoptosis of monocytes and prolonged survival of granulocytes as a result of phagocytosis of bacteria, Infect Immun, vol.64, pp.4242-4250, 1996. ,
Lipopolysaccharide, Microbiology and Immunology, vol.57, issue.6, pp.421-428, 2006. ,
DOI : 10.1111/j.1348-0421.2006.tb03810.x
MyD88, but Not Toll-Like Receptors 4 and 2, Is Required for Efficient Clearance of Brucella abortus, Infection and Immunity, vol.73, issue.8, pp.5137-5143, 2005. ,
DOI : 10.1128/IAI.73.8.5137-5143.2005
Lipopolysaccharide (LPS) from Brucella abortus is less toxic than that from Escherichia coli, suggesting the possible use of B. abortus or LPS from B. abortus as a carrier in vaccines, Infect Immun, vol.60, pp.1385-1394, 1992. ,
Interaction of endotoxins with Toll-like receptor 4 correlates with their endotoxic potential and may explain the proinflammatory effect of Brucella spp. LPS, International Immunology, vol.16, issue.10, pp.1467-75, 2004. ,
DOI : 10.1093/intimm/dxh148
Interleukin-8 delays spontaneous and tumor necrosis factor-??-mediated apoptosis of human neutrophils, Kidney International, vol.53, issue.1, pp.84-91, 1998. ,
DOI : 10.1046/j.1523-1755.1998.00741.x
Cytokine production of neutrophils is limited to interleukin-8, Immunology, vol.89, issue.4, pp.563-571, 1996. ,
DOI : 10.1046/j.1365-2567.1996.d01-784.x
Toll-Like Receptor (TLR)2 and TLR4 in Human Peripheral Blood Granulocytes: A Critical Role for Monocytes in Leukocyte Lipopolysaccharide Responses, The Journal of Immunology, vol.168, issue.9, pp.4701-4711, 2002. ,
DOI : 10.4049/jimmunol.168.9.4701
NF-kappa B Activation Is a Critical Regulator of Human Granulocyte Apoptosis in Vitro, Journal of Biological Chemistry, vol.274, issue.7, pp.4309-4327, 1999. ,
DOI : 10.1074/jbc.274.7.4309
Involvement of caspases in neutrophil apoptosis: regulation by reactive oxygen species, Blood, vol.92, pp.4808-4826, 1998. ,
Release of outer membrane fragments by exponentially growing Brucella melitensis cells, Infect Immun, vol.55, pp.609-624, 1987. ,
Brucella abortus activates human neutrophils, Microbes and Infection, vol.11, issue.6-7, pp.689-97, 2009. ,
DOI : 10.1016/j.micinf.2009.04.010
Differential inductions of TNF-alpha and IGTP, IIGP by structurally diverse classic and non-classic lipopolysaccharides, Cellular Microbiology, vol.168, issue.3, pp.401-414, 2006. ,
DOI : 10.1074/jbc.M313370200
Brucella abortus induces Irgm3 and Irga6 expression via type-I IFN by a MyD88-dependent pathway, without the requirement of TLR2, TLR4, TLR5 and TLR9, Microbial Pathogenesis, vol.47, issue.6, pp.299-304, 2009. ,
DOI : 10.1016/j.micpath.2009.09.005
URL : https://hal.archives-ouvertes.fr/hal-00431861
Azurophilic granules of human neutrophils contain CD14, Infect Immun, vol.65, pp.4747-53, 1997. ,
Characterization of Brucella abortus lipopolysaccharide macrodomains as mega rafts, Cellular Microbiology, vol.8, issue.2, pp.197-206, 2006. ,
DOI : 10.1074/jbc.M313370200
URL : https://hal.archives-ouvertes.fr/hal-00080755
Inhibition of mCD14 inhibits TNF?? secretion and NO production in RAW264.7 cells stimulated by Brucella melitensis infection, Veterinary Microbiology, vol.160, issue.3-4, p.22770519, 2012. ,
DOI : 10.1016/j.vetmic.2012.05.039
Brucella lipopolysaccharide acts as a virulence factor, Current Opinion in Microbiology, vol.8, issue.1, pp.60-66, 2005. ,
DOI : 10.1016/j.mib.2004.12.003
URL : https://hal.archives-ouvertes.fr/hal-00165710
Quantitation of surface neutrophils CD14 on human monocytes and, J Leukoc Biol, vol.61, pp.721-728, 1997. ,
Evades Macrophage Killing via VirB-dependent Sustained Interactions with the Endoplasmic Reticulum, The Journal of Experimental Medicine, vol.114, issue.4, pp.545-56, 2003. ,
DOI : 10.1038/35052017
Role of reactive oxygen species (ROS) in apoptosis induction, APOPTOSIS, vol.5, issue.5, pp.415-423, 2000. ,
DOI : 10.1023/A:1009616228304
NETosis and NADPH oxidase: at the intersection of host defense, inflammation, and injury, Frontiers in Immunology, vol.4, p.23459634, 2013. ,
DOI : 10.3389/fimmu.2013.00045
Chk1 suppressed cell death, Cell Division, vol.5, issue.1, p.20813042, 2010. ,
DOI : 10.1186/1747-1028-5-21
RIP1, a kinase on the crossroads of a cell's decision to live or die, Cell Death and Differentiation, vol.175, issue.3, pp.400-410, 2007. ,
DOI : 10.1084/jem.20050683
Charting calcium-regulated apoptosis pathways using chemical biology: role of calmodulin kinase II, BMC Chemical Biology, vol.8, issue.1, p.18673549, 2008. ,
DOI : 10.1186/1472-6769-8-2
Caspase-1-induced pyroptotic cell death, Immunological Reviews, vol.12, issue.1, pp.206-220, 2011. ,
DOI : 10.1111/j.1600-065X.2011.01044.x
Localization and Functionality of the Inflammasome in Neutrophils, Journal of Biological Chemistry, vol.289, issue.8, pp.5320-5329, 2014. ,
DOI : 10.1074/jbc.M113.505636
Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria, Nature Immunology, vol.180, issue.12, pp.1136-1178, 1960. ,
DOI : 10.1016/S1286-4579(01)01496-4
Pyroptosis: Macrophage Suicide Exposes Hidden Invaders, Current Biology, vol.21, issue.2, p.21256438, 2011. ,
DOI : 10.1016/j.cub.2010.12.008
Regulation of neutrophil apoptosis by tumor necrosis factor-alpha: requirement for TNFR55 and TNFR75 for induction of apoptosis in vitro, Blood, vol.90, pp.2772-2783, 1997. ,
TNF-??-induced apoptosis in neonatal lymphocytes: TNFRp55 expression and downstream pathways of apoptosis, Genes and Immunity, vol.1, issue.4, pp.271-280, 2000. ,
DOI : 10.1038/sj.gene.6363674
Bone marrow biopsy findings in brucellosis patients with hematologic abnormalities, Chin Med J (Engl), vol.125, pp.1871-1877, 2012. ,
A PROSPECTIVE STUDY OF BRUCELLOSIS IN CHILDREN: RELATIVE FREQUENCY OF PANCYTOPENIA, Mediterranean Journal of Hematology and Infectious Diseases, vol.5, issue.1, p.23505599, 2013. ,
DOI : 10.4084/mjhid.2013.011
Transient hemophagocytosis in Brucella melitensis infection, Arch Pathol Lab Med, vol.108, pp.213-219, 1984. ,
Neutrophil granulocytes ??? Trojan horses for Leishmania major and other intracellular microbes?, Trends in Microbiology, vol.11, issue.5, pp.210-214, 2003. ,
DOI : 10.1016/S0966-842X(03)00075-1
The use of green fluorescent protein as a marker for Brucella vaccines, Vaccine, vol.29, issue.3, pp.577-82, 2011. ,
DOI : 10.1016/j.vaccine.2010.09.109
Biological activities of Brucella abortus lipopolysaccharides, Infect Immun, vol.31, pp.362-70, 1981. ,
Comparative Light and Electron Microscopic Analyses of Tenuivirus Major Noncapsid Protein (NCP) Inclusion Bodies in Infected Plants, and of the NCP in Vitro, Virology, vol.195, issue.1, pp.156-66, 1993. ,
DOI : 10.1006/viro.1993.1356
Immunochemical identification of Brucella abortus lipopolysaccharide epitopes, Clin Diagn Lab Immunol, vol.1, pp.206-219, 1994. ,
THE USE OF LEAD CITRATE AT HIGH pH AS AN ELECTRON-OPAQUE STAIN IN ELECTRON MICROSCOPY, The Journal of Cell Biology, vol.17, issue.1, pp.208-220, 1963. ,
DOI : 10.1083/jcb.17.1.208
Definition of Brucella A and M epitopes by monoclonal typing reagents and synthetic oligosaccharides, Infect Immun, vol.57, pp.2829-2865, 1989. ,
Tilmicosin Induces Apoptosis in Bovine Peripheral Neutrophils in the Presence or in the Absence of Pasteurella haemolytica and Promotes Neutrophil Phagocytosis by Macrophages, Antimicrobial Agents and Chemotherapy, vol.44, issue.9, pp.2465-70, 2000. ,
DOI : 10.1128/AAC.44.9.2465-2470.2000
Brucella abortus 16S rRNA and lipid A reveal a phylogenetic relationship with members of the alpha-2 subdivision of the class Proteobacteria., Journal of Bacteriology, vol.172, issue.7, pp.3569-76, 1990. ,
DOI : 10.1128/jb.172.7.3569-3576.1990