TDAE Strategy in the Benzoxazolone Series: Synthesis and Reactivity of a New Benzoxazolinonic Anion

Aïda R. Nadji-Boukrouche (1, 2, 3) , Omar Khoumeri (1) , Thierry Terme (1) , Messaoud Liacha (3) , Patrice Vanelle (1)

1 ICR - Institut de Chimie Radicalaire
2 Département de Génie des Procédés
3 Laboratoire de Synthèse et de Biocatalyse Organique (LSBO)

We describe an original pathway to produce new 5-substituted 3-methyl-6-nitro-benzoxazolones by the reaction of aromatic carbonyl and α-carbonyl ester derivatives with a benzoxazolinonic anion formed exclusively via the TDAE strategy.

Keywords: TDAE; benzoxazolone; benzoxazolinonic anion; benzylic alcohols; oxiranes; ORIGINAL SYNTHESIS; DERIVATIVES; ALDEHYDES; LIGANDS; 2(3H)-BENZOXAZOLONE; METHODOLOGY; RING

Domains: Life Sciences [q-bio]; Biochemistry, Molecular Biology

Aïda R. Nadji-Boukrouche, Omar Khoumeri, Thierry Terme, Messaoud Liacha, Patrice Vanelle. TDAE Strategy in the Benzoxazolone Series: Synthesis and Reactivity of a New Benzoxazolinonic Anion. Molecules, 2015, 20, pp.1262-1276. ⟨10.3390/molecules20011262⟩. ⟨hal-01234886⟩