J. Amendola, D. , and J. , Morphological differences between wild-type and transgenic superoxide dismutase 1 lumbar motoneurons in postnatal mice, The Journal of Comparative Neurology, vol.27, issue.3, pp.329-341, 2008.
DOI : 10.1002/cne.21818

J. Amendola, J. P. Gueritaud, B. Lamotte-d-'incamps, C. Bories, S. Liabeuf et al., Postnatal electrical and morphological abnormalities in lumbar motoneurons from transgenic mouse models of amyotrophic lateral sclerosis, Arch. Ital. Biol, vol.145, pp.311-323, 2007.

J. Amendola, B. Verrier, P. Roubertoux, D. , J. K. Song et al., Altered sensorimotor development in a transgenic mouse model of amyotrophic lateral sclerosis, European Journal of Neuroscience, vol.84, issue.10, pp.2822-2826, 2004.
DOI : 10.1016/S0304-3940(02)00944-8
URL : https://hal.archives-ouvertes.fr/hal-00143638

D. J. Bennett, Y. Li, and M. Siu, Plateau potentials in sacrocaudal motoneurons of chronic spinal rats, recorded in vitro, J. Neurophysiol, vol.86, pp.1955-1971, 2001.

C. Bories, J. Amendola, B. Lamotte-d-'incamps, D. , and J. , Early electrophysiological abnormalities in lumbar motoneurons in a transgenic mouse model of amyotrophic lateral sclerosis, European Journal of Neuroscience, vol.76, issue.2, pp.451-459, 2007.
DOI : 10.1002/mus.20228
URL : https://hal.archives-ouvertes.fr/hal-00173820

F. Buchthal and H. Schmalbruch, Motor unit of mammalian muscle, Physiol. Rev, vol.60, pp.90-142, 1980.

M. Buffelli, G. Busetto, C. Bidoia, M. Favero, and A. Cangiano, Activitydependent synaptic competition at mammalian neuromuscular junctions, News Physiol. Sci, vol.19, pp.85-91, 2003.

M. Buffelli, G. Busetto, L. Cangiano, and A. Cangiano, Perinatal switch from synchronous to asynchronous activity of motoneurons: Link with synapse elimination, Proceedings of the National Academy of Sciences, vol.99, issue.20, pp.13200-13205, 2002.
DOI : 10.1073/pnas.202471199

K. P. Carlin, Z. Jiang, and R. M. Brownstone, Characterization of calcium currents in functionally mature mouse spinal motoneurons, European Journal of Neuroscience, vol.428, issue.5, 2000.
DOI : 10.1046/j.1460-9568.2000.00050.x

K. P. Carlin, J. Liu, J. , and L. M. , Postnatal Changes in the Inactivation Properties of Voltage-Gated Sodium Channels Contribute to the Mature Firing Pattern of Spinal Motoneurons, Journal of Neurophysiology, vol.99, issue.6, pp.2864-2876, 2008.
DOI : 10.1152/jn.00059.2008

L. Carrascal, J. L. Nieto-gonzalez, W. E. Cameron, B. Torres, and P. A. Nunez-abades, Changes during the postnatal development in physiological and anatomical characteristics of rat motoneurons studied in vitro, Brain Research Reviews, vol.49, issue.2, pp.377-387, 2005.
DOI : 10.1016/j.brainresrev.2005.02.003

N. Delestrée, M. Manuel, C. Iglesias, S. M. Elbasiouny, C. J. Heckman et al., Adult spinal motoneurones are not hyperexcitable in a mouse model of inherited amyotrophic lateral sclerosis, The Journal of Physiology, vol.96, issue.7, pp.1687-1703, 2014.
DOI : 10.1113/jphysiol.2013.265843

J. Durand, A. Filipchuk, A. Pambo-pambo, S. Liabeuf, C. Brocard et al., Low-excitable lumbar motoneurons are selectively affected in the spinal cord of postnatal transgenic SOD1?G93A mice, 2013.

J. Durand, Electrophysiological and morphological properties of rat abducens motoneurones, Experimental Brain Research, vol.76, issue.1, pp.141-152, 1989.
DOI : 10.1007/BF00253631

J. Durand, Intracellular study of oculomotor neurons in the rat, Neuroscience, vol.30, issue.3, pp.639-649, 1989.
DOI : 10.1016/0306-4522(89)90157-7

J. Durand, J. Amendola, C. Bories, and B. Lamotte-d-'incamps, Early abnormalities in transgenic mouse models of amyotrophic lateral sclerosis, Journal of Physiology-Paris, vol.99, issue.2-3, 2006.
DOI : 10.1016/j.jphysparis.2005.12.014
URL : https://hal.archives-ouvertes.fr/hal-00093914

S. M. Elbasiouny, J. Amendola, J. Durand, and C. J. Heckman, Evidence from Computer Simulations for Alterations in the Membrane Biophysical Properties and Dendritic Processing of Synaptic Inputs in Mutant Superoxide Dismutase-1 Motoneurons, Journal of Neuroscience, vol.30, issue.16, pp.5544-5558, 2010.
DOI : 10.1523/JNEUROSCI.0434-10.2010

A. A. Filipchuk, D. , and J. , Postnatal dendritic development in lumbar motoneurons in mutant superoxide dismutase 1 mouse model of amyotrophic lateral sclerosis, Neuroscience, vol.209, 2012.
DOI : 10.1016/j.neuroscience.2012.01.046

W. M. Fox, Reflex-ontogeny and behavioural development of the mouse, Animal Behaviour, vol.13, issue.2-3, pp.234-241, 1965.
DOI : 10.1016/0003-3472(65)90041-2

B. P. Fulton, W. , and K. , Electrophysiological properties of neonatal rat motoneurones studied in vitro., The Journal of Physiology, vol.370, issue.1, 1986.
DOI : 10.1113/jphysiol.1986.sp015956

B. X. Gao and L. Ziskind-conhaim, Development of ionic currents underlying changes in action potential waveforms in rat spinal motoneurons, J. Neurophysiol, vol.80, pp.3047-3061, 1998.

K. D. García, L. K. Sprunger, M. H. Meisler, and K. G. Beam, The sodium channel Scn8a is the major contributor to the postnatal developmental increase of sodium current density in spinal motoneurons, J. Neurosci, vol.18, pp.5234-5239, 1998.

M. Hadzipasic, B. Tahvildari, M. Nagy, M. Bian, A. L. Horwich et al., Selective degeneration of a physiological subtype of spinal motor neuron in mice with SOD1-linked ALS, Proceedings of the National Academy of Sciences, vol.111, issue.47, pp.16883-16888, 2014.
DOI : 10.1073/pnas.1419497111

C. Hammarberg, J. O. Kellerth, C. J. Heckman, M. Johnson, C. Mottram et al., The Postnatal Development of Some Twitch and Fatigue Properties of Single Motor Units in the Ankle Muscles of the Kitten, Acta Physiologica Scandinavica, vol.47, issue.Suppl. 260, pp.243-257, 1975.
DOI : 10.1111/j.1748-1716.1975.tb10048.x

J. Hounsgaard, H. Hultborn, B. Jespersen, and O. Kiehn, Bistability of alpha-motoneurones in the decerebrate cat and in the acute spinal cat after intravenous 5-hydroxytryptophan., The Journal of Physiology, vol.405, issue.1, pp.345-367, 1988.
DOI : 10.1113/jphysiol.1988.sp017336

Z. Jiang, K. P. Carlin, and R. M. Brownstone, An in vitro functionally mature mouse spinal cord preparation for the study of spinal motor networks, Brain Research, vol.816, issue.2, pp.493-499, 1999.
DOI : 10.1016/S0006-8993(98)01199-8

Z. Jiang, J. Rempel, J. Li, M. A. Sawchuk, K. P. Carlin et al., Development of L-type calcium channels and a nifedipine-sensitive motor activity in the postnatal mouse spinal cord, European Journal of Neuroscience, vol.8, issue.10, pp.3481-3487, 1999.
DOI : 10.1046/j.1460-9568.1999.00765.x

K. C. Kanning, A. Kaplan, H. , and C. E. , Motor Neuron Diversity in Development and Disease, Annual Review of Neuroscience, vol.33, issue.1, 2010.
DOI : 10.1146/annurev.neuro.051508.135722

J. O. Kellerth, A. Mellström, and S. Skoglund, Postnatal Excitability Changes of Kitten Motoneurones, Acta Physiologica Scandinavica, vol.7, issue.Suppl. 331, pp.31-41, 1971.
DOI : 10.1111/j.1748-1716.1971.tb05048.x

D. M. Kopp, D. J. Perkel, and R. J. Balice-gordon, Disparity in neurotransmitter release probability among competing inputs during neuromuscular synapse elimination, J. Neurosci, vol.20, pp.8771-8779, 2000.

F. Leroy, B. Lamotte-d-'incamps, R. D. Imhoff-manuel, and D. Zytnicki, Author response, eLife, vol.53, 2014.
DOI : 10.7554/eLife.04046.017

Y. Li, D. Brewer, R. E. Burke, and G. A. Ascoli, Developmental changes in spinal motoneuron dendrites in neonatal mice, The Journal of Comparative Neurology, vol.450, issue.7, pp.304-317, 2005.
DOI : 10.1002/cne.20438

J. G. Mclarnon, Potassium currents in motoneurones, Progress in Neurobiology, vol.47, issue.6, pp.513-531, 1995.
DOI : 10.1016/0301-0082(95)00032-1

G. Z. Mentis, E. Díaz, L. B. Moran, and R. Navarrete, Increased incidence of gap junctional coupling between spinal motoneurones following transient blockade of NMDA receptors in neonatal rats, The Journal of Physiology, vol.10, issue.98P, pp.757-764028159, 2002.
DOI : 10.1113/jphysiol.2002.028159

G. Z. Mentis, E. Díaz, L. B. Moran, and R. Navarrete, Early alterations in the electrophysiological properties of rat spinal motoneurones following neonatal axotomy, The Journal of Physiology, vol.10, issue.3, pp.1141-1161, 2007.
DOI : 10.1113/jphysiol.2007.133488

G. B. Miles, Y. Dai, and R. M. Brownstone, Mechanisms underlying the early phase of spike frequency adaptation in mouse spinal motoneurones, The Journal of Physiology, vol.74, issue.Suppl., pp.519-532086033, 2005.
DOI : 10.1113/jphysiol.2005.086033

D. Muller, P. Cherukuri, K. Henningfeld, C. H. Poh, L. Wittler et al., Dlk1 Promotes a Fast Motor Neuron Biophysical Signature Required for Peak Force Execution, Science, vol.343, issue.6176, pp.1264-1266, 2014.
DOI : 10.1126/science.1246448

M. Mynlieff and K. G. Beam, Characterization of voltage-dependent calcium currents in mouse motoneurons, J. Neurophysiol, vol.68, pp.85-92, 1992.

M. Mynlieff and K. G. Beam, Developmental expression of voltage-dependent calcium currents in identified mouse motoneurons, Developmental Biology, vol.152, issue.2, pp.407-410, 1992.
DOI : 10.1016/0012-1606(92)90148-A

S. T. Nakanishi and P. J. Whelan, Diversification of Intrinsic Motoneuron Electrical Properties During Normal Development and Botulinum Toxin-Induced Muscle Paralysis in Early Postnatal Mice, Journal of Neurophysiology, vol.103, issue.5, pp.2833-2845, 2010.
DOI : 10.1152/jn.00022.2010

R. Navarrette and G. Vrbová, Activity-dependent interactions between motoneurones and muscles: Their role in the development of the motor unit, Progress in Neurobiology, vol.41, issue.1, pp.93-124, 1993.
DOI : 10.1016/0301-0082(93)90041-P

J. L. Nieto-gonzalez, L. Carrascal, P. Nunez-abades, and B. Torres, Phasic and tonic firing properties in rat oculomotor nucleus motoneurons, studied in vitro Electrical properties of facial motoneurons in brainstem slices from guinea pig, Eur. J. Neurosci. Brain Res, vol.2589, issue.502, pp.2682-2696, 1989.

A. Pambo-pambo, J. Durand, and J. P. Gueritaud, Early Excitability Changes in Lumbar Motoneurons of Transgenic SOD1G85R and SOD1G93A-Low Mice, Journal of Neurophysiology, vol.102, issue.6, pp.3627-3642, 2009.
DOI : 10.1152/jn.00482.2009

J. F. Perrier and J. Hounsgaard, Development and regulation of response properties in spinal cord motoneurons, Brain Research Bulletin, vol.53, issue.5, pp.529-535, 2000.
DOI : 10.1016/S0361-9230(00)00386-5

K. E. Personius and R. J. Balice-gordon, Book Review: Activity-Dependent Synaptic Plasticity: Insights from Neuromuscular Junctions, The Neuroscientist, vol.395, issue.5, pp.414-422, 2002.
DOI : 10.1177/107385802236970

S. Pun, M. Sigrist, A. F. Santos, M. A. Ruegg, J. R. Sanes et al., An Intrinsic Distinction in Neuromuscular Junction Assembly and Maintenance in Different Skeletal Muscles, Neuron, vol.34, issue.3, pp.357-370, 2002.
DOI : 10.1016/S0896-6273(02)00670-0

K. A. Quinlan, J. B. Lamano, J. Samuels, and C. J. Heckman, Comparison of dendritic calcium transients in juvenile wild type and SOD1(G93A) mouse lumbar motoneurons, Front. Cell. Neurosci, 2015.

Z. A. Rana, K. Gundersen, and A. Buonanno, The ups and downs of gene regulation by electrical activity in skeletal muscles, Journal of Muscle Research and Cell Motility, vol.9, issue.4, pp.255-260, 2009.
DOI : 10.1007/s10974-010-9200-2

S. Saxena, F. Roselli, K. Singh, K. Leptien, J. P. Julien et al., Neuroprotection through Excitability and mTOR Required in ALS Motoneurons to Delay Disease and Extend Survival, Neuron, vol.80, issue.1, pp.80-96, 2013.
DOI : 10.1016/j.neuron.2013.07.027

P. C. Schwindt and W. E. Crill, Properties of a persistent inward current in normal and TEA-injected motoneurons, J. Neurophysiol, vol.43, pp.1700-1724, 1980.

B. S. Seebach and L. M. Mendell, Maturation in properties of motoneurons and their segmental input in the neonatal rat, J. Neurophysiol, vol.76, pp.3875-3885, 1996.

T. Takahashi, T. Takazawa, G. F. Croft, M. W. Amoroso, L. Studer et al., Membrane currents in visually identified motoneurones of neonatal rat spinal cord doi: 10.1113/jphysiol Maturation of spinal motor neurons derived from human embryonic stem cells, J. Physiol. PLoS One, vol.423, issue.7, pp.27-46, 1990.

L. Vinay, F. Ben-mabrouk, F. Brocard, F. Clarac, C. Jean-xavier et al., Perinatal Development of the Motor Systems Involved in Postural Control, Neural Plasticity, vol.12, issue.2-3, pp.131-139131, 2005.
DOI : 10.1155/NP.2005.131

L. Vinay, F. Brocard, C. , F. L. Brocard, F. Clarac et al., Differential maturation of motoneurons innervating ankle flexor and extensor muscles in the neonatal rat Development of posture and locomotion: an interplay of endogenously generated activities and neurotrophic actions by descending pathways, Eur. J. Neurosci. Brain Res. Brain Res. Rev, vol.12, issue.4002, pp.4562-4566, 2000.

L. Vinay, F. Brocard, J. F. Pflieger, J. Simeoni-alias, C. et al., Perinatal development of lumbar motoneurons and their inputs in the rat, Brain Research Bulletin, vol.53, issue.5, pp.635-647, 2000.
DOI : 10.1016/S0361-9230(00)00397-X

J. Zhu, F. Feng, K. Ni, Y. Zheng, and J. Zhang, Four subtypes of motor neurons exhibiting mutually exclusive firing patterns in the spinal ventral horn, Neuroscience Letters, vol.525, issue.2, pp.163-167, 2012.
DOI : 10.1016/j.neulet.2012.07.062

L. Ziskind-conhaim, Electrical properties of motoneurons in the spinal cord of rat embryos, Developmental Biology, vol.128, issue.1, pp.21-29, 1988.
DOI : 10.1016/0012-1606(88)90262-X

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