beta-Phosphorus hyperfine coupling constant in nitroxides: 5. Solvent effect

Gérard Audran (1) , Lionel Bosco (1) , Paul Brémond (1) , Teddy Butscher (1) , Jean-Michel Franconi (2) , Kuanysh Kabitaev , Marque S.R.A. (1) , Philippe Mellet (2) , Elodie Parzy (2) , Maurice Santelli (1) , Eric Thiaudiere (2) , Viel Stéphane (1)

1 ICR - Institut de Chimie Radicalaire
2 CRMSB - Centre de résonance magnétique des systèmes biologiques

Recently, we published the titration of water in organic solvents and conversely using this family of nitroxides (Org. Biomol. Chem. 2015 ASAP). In this article, we show that the a(beta,P) of persistent cyclic beta-phosphorylated nitroxides decreases with the normalized polarity Reichardt's constant E-T(N). Koppel-Palm and Kalmet-Abboud-Taft relationships were applied to get a deeper insight into the effects influencing a(N) and a(beta,P): polarity/polarizability, hydrogen bond donor property, and structuredness of the cybotactic region.

Keywords: AMINOXYL RADICALS; RING NITROXIDES; BOND HOMOLYSIS; POLARITY; EPR; ESR; RESONANCE; NITROGEN; PROBES; MRI

Domains: Chemical Sciences

Gérard Audran, Lionel Bosco, Paul Brémond, Teddy Butscher, Jean-Michel Franconi, et al.. beta-Phosphorus hyperfine coupling constant in nitroxides: 5. Solvent effect. RSC Advances, 2016, 6 (7), pp.5653-5670. ⟨10.1039/c5ra23521a⟩. ⟨hal-01408220⟩