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Organocatalytic Multicomponent Reactions of 1,3-Dicarbonyls for the Synthesis of Enantioenriched Heterocycles

Abstract : In this feature article, a general perspective of the research program aimed towards the preparation of polycyclic heterocycles by the means of enantioselective organocatalytic multicomponent reactions is presented. Guidelines for reaction design, including the selection of substrates and organocatalysts are discussed. For all transformations, scope and limitations are presented, along with post-functionalization to afford diversified heterocyclic scaffolds.
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https://hal.archives-ouvertes.fr/hal-01415048
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Submitted on : Monday, December 12, 2016 - 5:42:44 PM
Last modification on : Tuesday, December 14, 2021 - 8:36:12 AM
Long-term archiving on: : Monday, March 27, 2017 - 9:19:42 PM

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Haiying Du, Yohan Dudognon, M. del Mar Sanchez Duque, Sébastien Goudedranche, Damien Bonne, et al.. Organocatalytic Multicomponent Reactions of 1,3-Dicarbonyls for the Synthesis of Enantioenriched Heterocycles. SYNTHESIS, Georg Thieme Verlag, 2016, 48, pp.3479-3503. ⟨10.1055/s-0035-1561490⟩. ⟨hal-01415048⟩

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