An expeditious method for the selective cyclotrimerization of isocyanates initiated by TDAE

Alain G Giuglio-Tonolo (1) , Cédric Spitz (1) , Thierry Terme (1) , Patrice Vanelle (1)

1 ICR - Institut de Chimie Radicalaire

We developed a rapid and green synthesis of various isocyanurates by cyclotrimerization of isocyanates using TDAE (tetrakis(dimethylamino)ethylene). TDAE displays excellent performance in catalytic quantities , affording the corresponding trimer of isocyanates very rapidly, under air and at room temperature in good to excellent yields.

Keywords: Isocyanurates; TDAE; Solvent-free; Isocyanates; Cyclotrimerization

Domains: Chemical Sciences; Organic chemistry

Alain G Giuglio-Tonolo, Cédric Spitz, Thierry Terme, Patrice Vanelle. An expeditious method for the selective cyclotrimerization of isocyanates initiated by TDAE. Tetrahedron Letters, 2014, 55 (16), pp.2700 - 2702. ⟨10.1016/j.tetlet.2014.03.045⟩. ⟨hal-01425614⟩