Modelling the voltammetry of adsorbed enzymes and molecular catalysts

Vincent Fourmond (1) , Christophe Léger (1)

1 BIP - Bioénergétique et Ingénierie des Protéines

When redox enzymes are attached to electrodes and undergo direct electron transfer, their voltammetric responses exhibit diverse shapes that, if analysed correctly, may inform about various aspects of the catalytic mechanism. Here we review the models that have been proposed to interpret these signals in relation to the thermodynamics and kinetics of interfacial and intramolecular electron transfer and active site chemistry. We list the corresponding equations in forms that are ready to use for fitting, and the commands that run these fits in the open source software QSoas. We relate these models to those that have been used for characterizing small synthetic redox catalysts diffusing in solution.

Mots clés: Electrocatalysis; Molecular catalysts; Protein film voltammetry; Enzymes

Domaines: Chimie théorique et/ou physique; Autre

Vincent Fourmond, Christophe Léger. Modelling the voltammetry of adsorbed enzymes and molecular catalysts. Current Opinion in Electrochemistry, 2017, 1 (1), pp.110-120. ⟨10.1016/j.coelec.2016.11.002⟩. ⟨hal-01440516⟩