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A. We, P. Demange, and P. Ramos, The authors thank Dr Neil Johnson for the careful reading of the manuscript. This work was supported by grants from the « Institut National du Cancer » (PLBio2010 XXL-screen program) and the « Ligue Nationale Contre le Cancer, Equipe labellisée 2013). GM was supported by PhD fellowships from Ministère et de l' enseignement supérieur et de la Recherche