Unexpected palladium catalyzed O-arylation occurring in 4-(4-fluoro-3-nitrophenyl)-1,2-dimethyl-5-nitro-1H-imidazole series

Laura Zink , Kevin Neilde , Maxime D. Crozet (1) , Patrice Vanelle (2)

1 CBRL - Chimie, biologie et radicaux libres - UMR 6517
2 ICR - Institut de Chimie Radicalaire

We describe herein a new unexpected palladium-catalyzed O-arylation reaction in fluorinated nitro(o-nitrophenyl)imidazole series involving arylboronic acids under Suzuki-Miyaura cross-coupling reaction conditions. (C) 2012 Elsevier Ltd. All rights reserved.

Domaines: Chimie

Laura Zink, Kevin Neilde, Maxime D. Crozet, Patrice Vanelle. Unexpected palladium catalyzed O-arylation occurring in 4-(4-fluoro-3-nitrophenyl)-1,2-dimethyl-5-nitro-1H-imidazole series. Tetrahedron Letters, 2012, 53 (40), pp.5393--5397. ⟨10.1016/j.tetlet.2012.07.107⟩. ⟨hal-01460457⟩