Speeding-up enzyme-catalyzed synthesis of polyamides using omega-amino-alpha-alkoxy-acetate as monomer

Florent Poulhès (1) , Dominique Mouysset (1) , Gérard Gil (2) , Michèle P. Bertrand (1) , Stéphane Gastaldi (1)

1 ICR - Institut de Chimie Radicalaire
2 ISM2 - Institut des Sciences Moléculaires de Marseille

The design of omega-amino-alpha-alkoxy-acetate as monomer enables to dramatically speed up the formation of polyamides catalyzed by the supported lipase B of Candida antarctica. Only 30 min are needed to reach 93% conversion whereas 240 h are necessary to observe the same level of conversion with a monomer devoided of an oxygen atom in position beta relative to the electrophilic carbonyl group. Yields, Mn, Mw, DPn and PDI reach very good values for an enzymatic synthesis of polyamides. (C) 2013 Elsevier Ltd. All rights reserved.

Domaines: Chimie

Florent Poulhès, Dominique Mouysset, Gérard Gil, Michèle P. Bertrand, Stéphane Gastaldi. Speeding-up enzyme-catalyzed synthesis of polyamides using omega-amino-alpha-alkoxy-acetate as monomer. Polymer, 2013, 54 (14), pp.3467--3471. ⟨10.1016/j.polymer.2013.05.011⟩. ⟨hal-01460472⟩