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A new, rapid and sensitive bioluminescence assay for drug screening on Leishmania

Abstract : We validated anew method, based on luciferine/luciferase bioluminescence, for drug screening on promastigotes of different Leishmania species. Results obtained with this new, rapid, reproducible, and reliable method are in good accordance with results obtained by the conventional MTT assay. This bioluminescence assay has a lower detection limit. (C) 2013 Elsevier B.V. All rights reserved.
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Submitted on : Tuesday, February 7, 2017 - 4:43:53 PM
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Lucie Paloque, Nicolas Vidal, Magali Casanova, Aurélien Dumètre, Pierre Verhaeghe, et al.. A new, rapid and sensitive bioluminescence assay for drug screening on Leishmania. Journal of Microbiological Methods, Elsevier, 2013, 95 (3), pp.320--323. ⟨10.1016/j.mimet.2013.09.006⟩. ⟨hal-01460476⟩

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