Synthesis of Novel Highly Functionalized 4-Thiazolidinone Derivatives from 4-Phenyl-3-thiosemicarbazones

Abdelmadjid Benmohammed , Omar Khoumeri (1) , Ayada Djafri (2) , Thierry Terme (1) , Patrice Vanelle (1)

1 ICR - Institut de Chimie Radicalaire
2 Laboratoire Synthèse Organique Appliquée

We present herein the synthesis in good yields of two series of highly functionalized thiazolidinone derivatives from the reactions of various 4-phenyl-3-thio-semicarbazones with ethyl 2-bromoacetate and diethyl acetylenedicarboxylate, respectively.

Domains: Chemical Sciences

Abdelmadjid Benmohammed, Omar Khoumeri, Ayada Djafri, Thierry Terme, Patrice Vanelle. Synthesis of Novel Highly Functionalized 4-Thiazolidinone Derivatives from 4-Phenyl-3-thiosemicarbazones. Molecules, 2014, 19 (3), pp.3068--3083. ⟨10.3390/molecules19033068⟩. ⟨hal-01460500⟩