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Synthesis and Anti-Platelet Activity of Thiosulfonate Derivatives Containing a Quinone Moiety

Abstract : Thiosulfonate derivatives based on quinones were synthesized for studying "structure-activity relationship" compounds with an acylated and a free amino-group. Anti-platelet activity of the synthesized compounds was determined and the influence of substituents on the activity of the derivatives was assessed.
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Submitted on : Tuesday, February 7, 2017 - 5:01:23 PM
Last modification on : Thursday, January 18, 2018 - 1:56:16 AM

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Khrystyna Bolibrukh, Svyatoslav Polovkovych, Omar Khoumeri, Tetyana Halenova, Irina Nikolaeva, et al.. Synthesis and Anti-Platelet Activity of Thiosulfonate Derivatives Containing a Quinone Moiety. Scientia Pharmaceutica, 2015, 83 (2), pp.221--231. ⟨10.3797/scipharm.1411-14⟩. ⟨hal-01460551⟩

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