Introducing a New Dimension to Molecular Disease Classifications

Noémie Chiche (1, 2) , Laurent Chiche (3) , Damien Chaussabel (4)

1 VRCM - Vascular research center of Marseille
2 LA CONCEPTION - Hôpital de la Conception [CHU - APHM]
3 Hôpital Européen [Fondation Ambroise Paré - Marseille]
4 Sidra Medical and Research Center

Systemic lupus erythematosus (SLE) is an autoimmune disease presenting with a wide range of clinical manifestations. A recent study in Cell has uncovered distinct molecular classes of pediatric SLE patients. The approach employed is remarkable in that it may enable alignment of molecular classifications of disease with the development and selection of novel treatment modalities.

Mots clés: SYSTEMIC-LUPUS-ERYTHEMATOSUS; TRANSCRIPTIONAL REPERTOIRE ANALYSES; INTERFERON; BLOOD; SIGNATURES

Domaines: Sciences du Vivant [q-bio]

Noémie Chiche, Laurent Chiche, Damien Chaussabel. Introducing a New Dimension to Molecular Disease Classifications. Trends in Molecular Medicine, 2016, 22, pp.451-453. ⟨10.1016/j.molmed.2016.04.005⟩. ⟨hal-01467213⟩