Implementation of Syndromic Surveillance Systems in Two Rural Villages in Senegal

Cedric Abat (1) , Philippe Colson (1, 2) , Chaudet Hervé (1) , Jean-Marc Rolain (1, 2) , Hubert Bassene (1) , Aldiouma Diallo (1) , Oleg Mediannikov (1) , Florence Fenollar (1) , Didier Raoult (1) , Cheikh Sokhna (1)

1 URMITE - Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes
2 IHU Marseille - Institut Hospitalier Universitaire Méditerranée Infection

Infectious diseases still represent a major challenge for humanity. In this context, their surveillance is critical. From 2010 to 2016, two Point-Of-Care (POC) laboratories have been successfully implemented in the rural Saloum region of Senegal. In parallel, a homemade syndromic surveillance system called EPIMIC was implemented to monitor infectious diseases using data produced by the POC laboratory of the Timone hospital in Marseille, France. The aim of this study is to describe the steps necessary for implementing EPIMIC using data routinely produced by two POC laboratories (POC-L) established in rural Senegal villages. After improving EPIMIC, we started to monitor the 15 pathogens routinely diagnosed in the two POC-L using the same methodology we used in France. In 5 years, 2,577 deduplicated patients-samples couples from 775 different patients have been tested in the Dielmo and Ndiop POC-L. 739 deduplicated patients-samples couples were found to be positive to at least one of the tested pathogens. The retrospective analysis of the Dielmo and Ndiop POC data with EPIMIC allowed to generate 443 alarms. Since January 2016, 316 deduplicated patients-samples couples collected from 298 different patients were processed in the Niakhar POC laboratory. 56 deduplicated patients-samples couples were found to be positive to at least one of the tested pathogens. The retrospective analysis of the data of the Niakhar POC laboratory with EPIMIC allowed to generate 14 alarms. Although some improvements are still needed, EPIMIC has been successfully spread using data routinely produced by two rural POC-L in Senegal, West Africa.

Mots clés: Infectious disease surveillance; Senegal; Epidemiology; Pathogens; Bacterial pathogens; Infectious diseases; Africa; Borrelia

Domaines: Bactériologie; Virologie; Parasitologie; Cardiologie et système cardiovasculaire; Maladies émergentes; Maladies infectieuses

Cedric Abat, Philippe Colson, Chaudet Hervé, Jean-Marc Rolain, Hubert Bassene, et al.. Implementation of Syndromic Surveillance Systems in Two Rural Villages in Senegal. PLoS Neglected Tropical Diseases, 2016, 10 (12), pp.e0005212. ⟨10.1371/journal.pntd.0005212⟩. ⟨hal-01474346⟩