An ultrasensitive LC–MS/MS method with liquid phase extraction to determine paclitaxel in both cell culture medium and lysate promising quantification of drug nanocarriers release in vitro

Tarek Baati (1) , Thérèse Schembri (1) , Claude Villard (1) , Florian Correard (1, 2) , Diane Braguer (1, 2) , Marie-Anne Esteve (1, 2)

1 CRO2 - Centre de Recherches en Oncologie biologique et Oncopharmacologie
2 TIMONE - Hôpital de la Timone [CHU - APHM]

Domaines: Sciences pharmaceutiques

Tarek Baati, Thérèse Schembri, Claude Villard, Florian Correard, Diane Braguer, et al.. An ultrasensitive LC–MS/MS method with liquid phase extraction to determine paclitaxel in both cell culture medium and lysate promising quantification of drug nanocarriers release in vitro. Journal of Pharmaceutical and Biomedical Analysis, 2015, 115, pp.300 - 306. ⟨10.1016/j.jpba.2015.07.041⟩. ⟨hal-01478918⟩