cIMPACT-NOW (the consortium to inform molecular and practical approaches to CNS tumor taxonomy): a new initiative in advancing nervous system tumor classification

David N N.Louis (1) , Ken M Aldape (2) , Daniel J. M Brat (3) , David N Capper (4) , David N Ellison (5) , Cynthia M Hawkins (6) , Werner N Paulus (7) , Arie Perry (8) , Guido N Reifenberger (9) , Dominique N Figarella-Branger (10) , Pieter N Wesseling (11) , Tracy T. N Batchelor (12) , J. Gregory N Cairncross (13) , Stefan N Pfister (14) , Stefan M Rutkowski (15) , Michael N Weller (16) , Wolfgang N Wick (17) , Andreas von Deimling (4)

1 Department of Pathology
2 Department of Pathology
3 Department of Pathology and Laboratory Medicine
4 Department of Neuropathology
5 Department of Pathology
6 Department of Paediatric Laboratory Medicine
7 Institute of Neuropathology
8 Department of Pathology
9 Department of Neuropathology
10 TIMONE - Hôpital de la Timone [CHU - APHM]
11 Department of Pathology
12 Department of Neurology
13 Department of Clinical Neurosciences
14 Department of Pediatric Oncology, Hematology, & Immunology
15 Department of Pediatric Haematology and Oncology
16 Department of Neurology
17 Clinical Cooperation Unit Neuropathology

The 2016 World Health Organization Classification of Tumors of the Central Nervous System (2016 CNS WHO) is a major shift in the way neuropathologists analyze and diagnose brain tumors as it incorporates molecular and histological information together to define many entities (1). While the 2016 CNS WHO thereby facilitates more precise diagnosis of well-understood entities and clearer designation of less-understood entities, it also presents a number of practical challenges for neuropathologists, requiring substantial shifts in their day-to-day practices (2). Nonetheless, neuropathologiste will learn the system readily over time, and will adapt as needed to the new requirements.

Mots clés: Classification of Tumors; neuropathologiste; brain tumors

Domaines: Cancer; Neurobiologie

David N N.Louis, Ken M Aldape, Daniel J. M Brat, David N Capper, David N Ellison, et al.. cIMPACT-NOW (the consortium to inform molecular and practical approaches to CNS tumor taxonomy): a new initiative in advancing nervous system tumor classification. Brain Pathology, 2016, ⟨10.1111/bpa.12457⟩. ⟨hal-01480029⟩