R. Salvatella, Andean subregional Chagas disease area and the Andean Initiative of Chagas Disease, Mem??rias do Instituto Oswaldo Cruz, vol.102, issue.suppl 1, 2007.
DOI : 10.1590/S0074-02762007005000105

URL : http://www.scielo.br/pdf/mioc/v102s1/cd_4.pdf

L. Kirchhoff, L. Weiss, M. Wittner, and H. Tanowitz, Parasitic diseases of the heart, Frontiers in Bioscience, vol.9, issue.1-3, pp.706-723, 2004.
DOI : 10.2741/1255

C. Schofield, J. Jannin, and R. Salvatella, The future of Chagas disease control, Trends in Parasitology, vol.22, issue.12, 2006.
DOI : 10.1016/j.pt.2006.09.011

E. Dias, F. Laranja, A. Miranda, and G. Nobrega, Chagas' disease; a clinical, epidemiologic, and pathologic study, Circulation, vol.14, 1956.

U. Martin, D. Afchain, A. De-marteleur, O. Ledesma, and A. Capron, Circulating immune complexes in different developmental stages of Chagas' disease, Medicina (B Aires), vol.47, pp.159-162, 1987.

J. Coura, Chagas disease: what is known and what is needed - A background article, Mem??rias do Instituto Oswaldo Cruz, vol.34, issue.suppl 1, pp.113-122, 2007.
DOI : 10.1093/jee/44.1.52

C. Mady, R. Cardoso, A. Barretto, P. Da-luz, and G. Bellotti, Survival and predictors of survival in patients with congestive heart failure due to Chagas' cardiomyopathy, Circulation, vol.90, issue.6, pp.3098-3102, 1994.
DOI : 10.1161/01.CIR.90.6.3098

URL : http://circ.ahajournals.org/content/circulationaha/90/6/3098.full.pdf

R. Bestetti and G. Muccillo, Clinical course of Chagas' heart disease: a comparison with dilated cardiomyopathy, International Journal of Cardiology, vol.60, issue.2, pp.187-19310, 1997.
DOI : 10.1016/S0167-5273(97)00083-1

P. Barretto, A. Mady, C. Arteaga-fernandez, E. Stolf, N. Lopes et al., Right ventricular endomyocardial biopsy in chronic Chagas' disease, American Heart Journal, vol.111, issue.2, pp.307-312, 1986.
DOI : 10.1016/0002-8703(86)90144-4

M. Higuchi, D. Morais, C. , P. Barreto, A. Lopes et al., The Role of active myocarditis in the development of heart failure in chronic chagas' disease: A study based on endomyocardial biopsies, Clinical Cardiology, vol.28, issue.2, pp.665-670, 1987.
DOI : 10.1590/S0036-46651986000200004

M. Ribeirao, V. Pereira-chioccola, L. Renia, F. Filho-augusto, A. Schenkman et al., Chagasic patients develop a type 1 immune response to Trypanosoma cruzi trans-sialidase, Parasite Immunology, vol.22, issue.1, 2000.
DOI : 10.1046/j.1365-3024.2000.00260.x

L. Abel, L. Rizzo, B. Ianni, F. Albuquerque, and F. Bacal, Chronic Chagas' disease cardiomyopathy patients display an increased IFN-gamma response to Trypanosoma cruzi infection, J Autoimmun, vol.17, 2001.
DOI : 10.1006/jaut.2001.0523

M. Teixeira, R. Gazzinelli, and J. Silva, Chemokines, inflammation and Trypanosoma cruzi infection, Trends in Parasitology, vol.18, issue.6, pp.262-265, 2002.
DOI : 10.1016/S1471-4922(02)02283-3

R. Ferreira, B. Ianni, L. Abel, P. Buck, and C. Mady, Increased plasma levels of tumor necrosis factor-alpha in asymptomatic/"indeterminate" and Chagas disease cardiomyopathy patients, Mem??rias do Instituto Oswaldo Cruz, vol.32, issue.3, pp.407-418, 2003.
DOI : 10.1590/S0037-86821999000300010

URL : http://www.scielo.br/pdf/mioc/v98n3/a21v98n3.pdf

A. Talvani, M. Rocha, L. Barcelos, Y. Gomes, and A. Ribeiro, Elevated concentrations of CCL2 and tumor necrosis factoralpha in chagasic cardiomyopathy, Clin Infect Dis, vol.38, p.15034825, 2004.
DOI : 10.1086/381892

URL : https://academic.oup.com/cid/article-pdf/38/7/943/916374/38-7-943.pdf

L. Nogueira, R. Santos, B. Ianni, A. Fiorelli, and E. Mairena, Myocardial Chemokine Expression and Intensity of Myocarditis in Chagas Cardiomyopathy Are Controlled by Polymorphisms in CXCL9 and CXCL10, PLoS Neglected Tropical Diseases, vol.93, issue.1, p.1867, 2012.
DOI : 10.1371/journal.pntd.0001867.s012

URL : https://doi.org/10.1371/journal.pntd.0001867

E. Cunha-neto, V. Dzau, P. Allen, D. Stamatiou, and L. Benvenutti, Cardiac Gene Expression Profiling Provides Evidence for Cytokinopathy as a Molecular Mechanism in Chagas' Disease Cardiomyopathy, The American Journal of Pathology, vol.167, issue.2, pp.305-31310, 2005.
DOI : 10.1016/S0002-9440(10)62976-8

L. Riol-blanco, N. Sánchez-sánchez, A. Torres, A. Tejedor, and S. Narumiya, The Chemokine Receptor CCR7 Activates in Dendritic Cells Two Signaling Modules That Independently Regulate Chemotaxis and Migratory Speed, The Journal of Immunology, vol.174, issue.7, pp.4070-4080, 2005.
DOI : 10.4049/jimmunol.174.7.4070

URL : http://www.jimmunol.org/content/jimmunol/174/7/4070.full.pdf

N. Sakai, T. Wada, H. Yokoyama, M. Lipp, and S. Ueha, Secondary lymphoid tissue chemokine (SLC/CCL21)/CCR7 signaling regulates fibrocytes in renal fibrosis, Proceedings of the National Academy of Sciences, vol.99, issue.9, pp.14098-14103, 2006.
DOI : 10.1097/01.ASN.0000120371.09769.80

URL : http://www.pnas.org/content/103/38/14098.full.pdf

V. Reddy, R. Harskamp, M. Van-ginkel, J. Calhoon, and C. Baisden, Interleukin-18 stimulates fibronectin expression in primary human cardiac fibroblasts via PI3K-Akt-dependent NF-??B activation, Journal of Cellular Physiology, vol.289, issue.3, pp.697-707, 2008.
DOI : 10.1161/01.CIR.83.6.1849

T. Kubota, G. Bounoutas, M. Miyagishima, T. Kadokami, and V. Sanders, Soluble Tumor Necrosis Factor Receptor Abrogates Myocardial Inflammation but Not Hypertrophy in Cytokine-Induced Cardiomyopathy, Circulation, vol.101, issue.21, pp.2518-2525, 2000.
DOI : 10.1161/01.CIR.101.21.2518

URL : http://circ.ahajournals.org/content/101/21/2518.full.pdf

K. Reifenberg, H. Lehr, M. Torzewski, G. Steige, and E. Wiese, Interferon-?? Induces Chronic Active Myocarditis and Cardiomyopathy in Transgenic Mice, The American Journal of Pathology, vol.171, issue.2, pp.463-472, 2007.
DOI : 10.2353/ajpath.2007.060906

URL : http://europepmc.org/articles/pmc1934522?pdf=render

A. Bilate, V. Salemi, F. Ramires, T. De-brito, and A. Silva, The Syrian hamster as a model for the dilated cardiomyopathy of Chagas??? disease: a quantitative echocardiographical and histopathological analysis, Microbes and Infection, vol.5, issue.12, 2003.
DOI : 10.1016/j.micinf.2003.07.001

F. Zicker, P. Smith, J. Netto, R. Oliveira, and E. Zicker, Physical Activity, Opportunity for Reinfection, and Sibling History of Heart Disease as Risk Factors for Chagas' Cardiopathy, The American Journal of Tropical Medicine and Hygiene, vol.43, issue.5, pp.498-505, 1990.
DOI : 10.4269/ajtmh.1990.43.498

R. Ramasawmy, E. Cunha-neto, K. Fae, F. Martello, and N. Müller, The Monocyte Chemoattractant Protein???1 Gene Polymorphism Is Associated with Cardiomyopathy in Human Chagas Disease, Clinical Infectious Diseases, vol.62, issue.3, pp.305-31110, 2006.
DOI : 10.1007/s102380200017

URL : https://academic.oup.com/cid/article-pdf/43/3/305/950728/43-3-305.pdf

E. Cunha-neto, L. Nogueira, P. Teixeira, R. Ramasawmy, and S. Drigo, Immunological and non-immunological effects of cytokines and chemokines in the pathogenesis of chronic Chagas disease cardiomyopathy, Mem??rias do Instituto Oswaldo Cruz, vol.43, issue.suppl 1, pp.252-258, 2009.
DOI : 10.4269/ajtmh.1990.43.498

P. Teixeira, A. Frade, L. Nogueira, J. Kalil, and C. Chevillard, Pathogenesis of Chagas disease cardiomyopathy, World Journal of Clinical Infectious Diseases, vol.2, issue.3, pp.39-53, 2012.
DOI : 10.5495/wjcid.v2.i3.39

URL : https://hal.archives-ouvertes.fr/hal-01592690

F. Ahmad, J. Seidman, and C. Seidman, THE GENETIC BASIS FOR CARDIAC REMODELING, Annual Review of Genomics and Human Genetics, vol.6, issue.1, pp.185-216, 2005.
DOI : 10.1146/annurev.genom.6.080604.162132

L. Dellefave and E. Mcnally, The genetics of dilated cardiomyopathy, Current Opinion in Cardiology, vol.25, issue.3, pp.198-204, 2010.
DOI : 10.1097/HCO.0b013e328337ba52

M. Lu, C. Dilullo, T. Schultheiss, S. Holtzer, and J. Murray, The vinculin/sarcomeric-alpha-actinin/alpha-actin nexus in cultured cardiac myocytes, The Journal of Cell Biology, vol.117, issue.5, 1992.
DOI : 10.1083/jcb.117.5.1007

URL : http://jcb.rupress.org/content/jcb/117/5/1007.full.pdf

C. Gregorio, Models of Thin Filament Assembly in Cardiac and Skeletal Muscle., Cell Structure and Function, vol.22, issue.1, pp.191-195, 1997.
DOI : 10.1247/csf.22.191

URL : https://www.jstage.jst.go.jp/article/csf1975/22/1/22_1_191/_pdf

T. Olson, V. Michels, S. Thibodeau, Y. Tai, and M. Keating, Actin Mutations in Dilated Cardiomyopathy, a Heritable Form of Heart Failure, Science, vol.280, issue.5364, pp.750-752, 1998.
DOI : 10.1126/science.280.5364.750

H. Jiang, G. Qiu, J. Li-ling, N. Xin, and K. Sun, Reduced ACTC1 Expression Might Play a Role in the Onset of Congenital Heart Disease by Inducing Cardiomyocyte Apoptosis, Circulation Journal, vol.74, issue.11, 2010.
DOI : 10.1253/circj.CJ-10-0234

S. Tostes, . Jr, D. Rocha-rodrigues, G. De-araujo-pereira, and V. Rodrigues, Myocardiocyte apoptosis in heart failure in chronic Chagas' disease, International Journal of Cardiology, vol.99, issue.2, pp.233-240, 2005.
DOI : 10.1016/j.ijcard.2004.01.026

R. Foo, K. Mani, and R. Kitsis, Death begets failure in the heart, Journal of Clinical Investigation, vol.115, issue.3, pp.565-571, 2005.
DOI : 10.1172/JCI24569DS1

URL : http://www.jci.org/articles/view/24569/files/pdf

A. Bilate, P. Teixeira, S. Ribeiro, B. Td, and A. Silva, Infection in Hamsters Are Related to Myocardial Parasitism, Cytokine/Chemokine Gene Expression, and Protein Expression Profile, The Journal of Infectious Diseases, vol.28, issue.4, pp.614-623, 2008.
DOI : 10.1016/j.bbabio.2006.03.008

URL : https://academic.oup.com/jid/article-pdf/198/4/614/18055194/198-4-614.pdf

M. Jorge, T. Macedo, R. Janones, D. Carizzi, and R. Heredia, Types of arrhythmia among cases of American trypanosomiasis, compared with those in other cardiology patients, Annals of Tropical Medicine & Parasitology, vol.60, issue.2, pp.139-148, 2003.
DOI : 10.1016/0002-9149(72)90417-1

D. Van-veldhuisen, G. Linssen, T. Jaarsma, W. Van-gilst, and A. Hoes, B-Type Natriuretic Peptide and Prognosis in Heart Failure Patients With Preserved and Reduced Ejection Fraction, Journal of the American College of Cardiology, vol.61, issue.14, pp.1498-1506, 2013.
DOI : 10.1016/j.jacc.2012.12.044

J. Januzzi and . Jr, Natriuretic Peptides, Ejection Fraction, and Prognosis, Journal of the American College of Cardiology, vol.61, issue.14, pp.1507-150910, 2013.
DOI : 10.1016/j.jacc.2013.01.039

URL : https://doi.org/10.1016/j.jacc.2013.01.039

P. Teixeira, R. Santos, A. Fiorelli, A. Bilate, and L. Benvenuti, Selective Decrease of Components of the Creatine Kinase System and ATP Synthase Complex in Chronic Chagas Disease Cardiomyopathy, PLoS Neglected Tropical Diseases, vol.75, issue.6, p.1205, 2011.
DOI : 10.1371/journal.pntd.0001205.s001

T. Schmittgen and K. Livak, Analyzing real-time PCR data by the comparative C(T), Methods -Nat Protoc, vol.3, 2008.
DOI : 10.1038/nprot.2008.73

A. Barretto, E. Arteaga, C. Mady, B. Ianni, and G. Bellotti, Male sex. Prognostic factor in Chagas' disease, Arq Bras Cardiol, vol.60, pp.225-227, 1993.

K. Faé, S. Drigo, E. Cunha-neto, B. Ianni, and C. Mady, HLA and ??-myosin heavy chain do not influence susceptibility to Chagas' disease cardiomyopathy, Microbes and Infection, vol.2, issue.7, pp.745-75110, 2000.
DOI : 10.1016/S1286-4579(00)00501-3

A. Basquiera, A. Sembaj, A. Aguerri, M. Omelianiuk, and S. Guzmán, Risk progression to chronic Chagas cardiomyopathy: influence of male sex and of parasitaemia detected by polymerase chain reaction, Heart, vol.89, issue.10, 2003.
DOI : 10.1136/heart.89.10.1186

D. Nyholt, A Simple Correction for Multiple Testing for Single-Nucleotide Polymorphisms in Linkage Disequilibrium with Each Other, The American Journal of Human Genetics, vol.74, issue.4, pp.765-769, 2004.
DOI : 10.1086/383251

URL : https://doi.org/10.1086/383251

D. Nyholt, Evaluation of Nyholt???s Procedure for Multiple Testing Correction ??? Author???s Reply, Human Heredity, vol.60, issue.1, pp.61-62, 2005.
DOI : 10.1159/000087919

A. Isnard, B. Kouriba, O. Doumbo, and C. Chevillard, Association of rs7719175, located in the IL13 gene promoter, with Schistosoma haematobium infection levels and identification of a susceptibility haplotype, Genes & Immunity, vol.2, issue.1, pp.31-39, 2011.
DOI : 10.1093/bioinformatics/bth457

URL : https://hal.archives-ouvertes.fr/hal-01612080

C. Beall, M. Sepanski, and E. Fyrberg, Genetic dissection of Drosophila myofibril formation: effects of actin and myosin heavy chain null alleles., Genes & Development, vol.3, issue.2, pp.131-140, 1989.
DOI : 10.1101/gad.3.2.131

URL : http://genesdev.cshlp.org/content/3/2/131.full.pdf

M. Krüger and W. Linke, Titin-based mechanical signalling in normal and failing myocardium, Journal of Molecular and Cellular Cardiology, vol.46, issue.4, pp.490-498, 2009.
DOI : 10.1016/j.yjmcc.2009.01.004

R. Knoll, B. Buyandelger, and M. Lab, The sarcomeric Z-disc and Zdiscopathies, J Biomed Biotechnol, p.569628, 2011.

K. Pulkki, Cytokines and Cardiomyocyte Death, Annals of Medicine, vol.60, issue.1, pp.339-343, 1997.
DOI : 10.1097/00007890-199511270-00010

A. Mocelin, V. Issa, F. Bacal, G. Guimarães, and E. Cunha, The influence of aetiology on inflammatory and neurohumoral activation in patients with severe heart failure: A prospective study comparing Chagas' heart disease and idiopathic dilated cardiomyopathy, European Journal of Heart Failure, vol.60, issue.5, p.16043406, 2005.
DOI : 10.1016/S0167-5273(97)00083-1