Skip to Main content Skip to Navigation
New interface
Journal articles

Genetics of parasitic infections

Abstract : Parasites cause much suffering mainly in countries of the southern hemisphere. Hundreds of millions of individuals are infected by schistosomes, leishmanias, plasmodiums, trypanosomes, and various other parasites, and severe clinical disease occurs in a sizable fraction of the infected population causing death and severe sequelae. The outcome, asymptomatic, subclinical or clinical disease, of an infection depends mostly on the parasite and on its host. Several groups analyzing the genetics of human susceptibility to parasites have began to identify the critical steps of the pathogenic mechanisms in a few parasitic infections such as malaria and schistosomiasis. The present article, which is not meant to be an exhaustive review of the field, illustrates the progresses made in this field from pioneer studies in animals to works in endemic populations using modern strategies of human genetics.
Document type :
Journal articles
Complete list of metadata

Cited literature [43 references]  Display  Hide  Download
Contributor : Lionel Spinelli Connect in order to contact the contributor
Submitted on : Thursday, December 6, 2018 - 10:10:14 AM
Last modification on : Friday, March 4, 2022 - 9:36:03 AM
Long-term archiving on: : Thursday, March 7, 2019 - 1:09:10 PM


Article 15 (2001).pdf
Publication funded by an institution


Distributed under a Creative Commons Attribution 4.0 International License


  • HAL Id : hal-01593091, version 1



Alain J. Dessein, Christophe Chevillard, S Marquet, Sandrine Henri, Dominique Hillaire, et al.. Genetics of parasitic infections. Drug Metabolism and Disposition, 2001, 29 (4), pp.484-488. ⟨hal-01593091⟩



Record views


Files downloads