Immunological Synapse, 2015. ,
Altered chemokine production and accumulation of regulatory T cells in intestinal adenomas of APCMin/+ mice, Cancer Immunology, Immunotherapy, vol.122, issue.8, pp.807-819, 2014. ,
DOI : 10.1172/JCI62110
Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction., Genes & Development, vol.11, issue.7, pp.824-834, 1997. ,
DOI : 10.1101/gad.11.7.824
Nuclear Export of NF-ATc Enhanced by Glycogen Synthase Kinase-3, Science, vol.275, issue.5308, 1930. ,
DOI : 10.1126/science.275.5308.1930
APC gene: database of germline and somatic mutations in human tumors and cell lines, Nucleic Acids Research, vol.24, issue.1, pp.121-124, 1996. ,
DOI : 10.1093/nar/24.1.121
Activation of the Ancestral Polarity Regulator Protein Kinase C?? at the Immunological Synapse Drives Polarization of Th Cell Secretory Machinery toward APCs, The Journal of Immunology, vol.185, issue.5, pp.2887-2894, 2010. ,
DOI : 10.4049/jimmunol.1000739
T cell receptor ligation induces the formation of dynamically regulated signaling assemblies, The Journal of Cell Biology, vol.115, issue.7, pp.1263-1275, 2002. ,
DOI : 10.1016/S1074-7613(00)80606-8
Actin and agonist MHC???peptide complex???dependent T cell receptor microclusters as scaffolds for signaling, The Journal of Experimental Medicine, vol.114, issue.8, 2005. ,
DOI : 10.1038/nature03391
Spontaneous intestinal tumorigenesis in Apc (/Min+) mice requires altered T cell development with IL-17A, J. Immunol, 2015. ,
Oral Interleukin-10 Alleviates Polyposis via Neutralization of Pathogenic T-Regulatory Cells, Cancer Research, vol.74, issue.19, pp.5377-5385, 2014. ,
DOI : 10.1158/0008-5472.CAN-14-0918
Activation-Induced Polarized Recycling Targets T Cell Antigen Receptors to the Immunological Synapse, Immunity, vol.20, issue.5, pp.577-588, 2004. ,
DOI : 10.1016/S1074-7613(04)00106-2
URL : https://hal.archives-ouvertes.fr/pasteur-00137478
T-cell Expression of IL10 Is Essential for Tumor Immune Surveillance in the Small Intestine, Cancer Immunology Research, vol.3, issue.7, pp.806-814, 2015. ,
DOI : 10.1158/2326-6066.CIR-14-0169
A novel pathway down-modulating T cell activation involves HPK-1???dependent recruitment of 14-3-3 proteins on SLP-76, The Journal of Experimental Medicine, vol.15, issue.3, pp.681-691, 2007. ,
DOI : 10.1074/jbc.272.15.9979
URL : https://hal.archives-ouvertes.fr/pasteur-01372621
Beta-catenin inhibits T cell activation by selective interference with linker for activation of T cells-phospholipase C-g1 phosphorylation, 2011. ,
Centrosome positioning in polarized cells: Common themes and variations, Experimental Cell Research, vol.328, issue.2, pp.240-248, 2014. ,
DOI : 10.1016/j.yexcr.2014.09.004
Mice, Cancer Research, vol.65, issue.10, pp.3998-4004, 2005. ,
DOI : 10.1158/0008-5472.CAN-04-3104
APC in Cell Migration, Adv. Exp. Med. Biol, vol.656, pp.30-40, 2009. ,
DOI : 10.1007/978-1-4419-1145-2_3
Cdc42 and Par6???PKC?? regulate the spatially localized association of Dlg1 and APC to control cell polarization, The Journal of Cell Biology, vol.14, issue.6, pp.895-901, 2005. ,
DOI : 10.1083/jcb.134.6.1469
Loss of adenomatous polyposis coli gene function disrupts thymic development, Nature Immunology, vol.15, issue.8, pp.800-809, 2005. ,
DOI : 10.3109/08830189709068173
Mast cells are an essential hematopoietic component for polyp development, Proc. Natl, 2007. ,
DOI : 10.1038/nm1649
T-Regulatory Cells Shift from a Protective Anti-Inflammatory to a Cancer-Promoting Proinflammatory Phenotype in Polyposis, Cancer Research, vol.69, issue.13, pp.5490-5497, 2009. ,
DOI : 10.1158/0008-5472.CAN-09-0304
The beta-cate- nin?TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival, Nature Immunology, vol.8, issue.8, pp.691-697, 2001. ,
DOI : 10.1038/90623
Cutting Edge: Tubulin ?? Functions as an Adaptor in NFAT-Importin ?? Interaction, The Journal of Immunology, vol.186, issue.5, 2011. ,
DOI : 10.4049/jimmunol.1003322
Smad4 signalling in T cells is required for suppression of gastrointestinal cancer, Nature, vol.21, issue.7096, pp.1015-1019, 2006. ,
DOI : 10.4161/cc.4.2.1413
Lack of Adenomatous Polyposis Coli Protein Correlates with a Decrease in Cell Migration and Overall Changes in Microtubule Stability, Molecular Biology of the Cell, vol.18, issue.3, pp.910-918, 2007. ,
DOI : 10.1091/mbc.E06-03-0179
Ezrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse, The EMBO Journal, vol.161, issue.14, pp.2301-2314, 2010. ,
DOI : 10.1038/ni1272
URL : https://hal.archives-ouvertes.fr/pasteur-00593159
Release of serine/threonine-phosphorylated adaptors from signaling microclusters down-regulates T cell activation, The Journal of Cell Biology, vol.195, issue.5, pp.839-853, 2011. ,
DOI : 10.1038/ni1272
URL : https://hal.archives-ouvertes.fr/pasteur-00646203
Constitutive Nuclear Localization of NFAT in Foxp3+ Regulatory T Cells Independent of Calcineurin Activity, The Journal of Immunology, vol.188, issue.9, pp.4268-4277, 2012. ,
DOI : 10.4049/jimmunol.1102376
T cells, The Journal of Experimental Medicine, vol.205, issue.6, pp.1381-1393, 2008. ,
DOI : 10.1084/jem.20071451
URL : https://hal.archives-ouvertes.fr/pasteur-01402753
Stabilisation of ??-Catenin Downstream of T Cell Receptor Signalling, PLoS ONE, vol.3, issue.9, 2010. ,
DOI : 10.1371/journal.pone.0012794.g006
A Network of PDZ-Containing Proteins Regulates T Cell Polarity and Morphology during Migration and Immunological Synapse Formation, Immunity, vol.22, issue.6, pp.737-748, 2005. ,
DOI : 10.1016/j.immuni.2005.04.009
Transcriptional Mechanisms Underlying Lymphocyte Tolerance, Cell, vol.109, issue.6, pp.719-731, 2002. ,
DOI : 10.1016/S0092-8674(02)00767-5
Zinc and the cytoskeleton in the neuronal modulation of transcription factor NFAT, Journal of Cellular Physiology, vol.7, issue.1, pp.246-256, 2007. ,
DOI : 10.1128/MCB.17.3.1522
The Transcription Factor NFAT Promotes Exhaustion of Activated CD8 + T Cells, Immunity, vol.42, issue.2, pp.265-278, 2015. ,
DOI : 10.1016/j.immuni.2015.01.006
Cell regulation by the Apc protein, Current Opinion in Cell Biology, vol.20, issue.2, pp.186-193, 2008. ,
DOI : 10.1016/j.ceb.2008.02.001
The adenomatous polyposis coli protein unambiguously localizes to microtubule plus ends and is involved in establishing parallel arrays of microtubule bundles in highly polarized epithelial cells, The Journal of Cell Biology, vol.108, issue.6, pp.1041-1048, 2002. ,
DOI : 10.1016/S0960-9822(01)00002-1
A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse, Science, vol.247, issue.4940, pp.322-324, 1990. ,
DOI : 10.1126/science.2296722
The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration, The Journal of Cell Biology, vol.134, issue.1, pp.165-179, 1996. ,
DOI : 10.1083/jcb.134.1.165
Interactions and functions of the adenomatous polyposis coli (APC) protein at a glance, Journal of Cell Science, vol.126, issue.4, pp.873-877, 2013. ,
DOI : 10.1242/jcs.100479
The microbiota regulates type 2 immunity through ROR??t+ T cells, Science, vol.12, issue.4, pp.989-993, 2015. ,
DOI : 10.1038/ni.2002
Concerted Dephosphorylation of the Transcription Factor NFAT1 Induces a Conformational Switch that Regulates Transcriptional Activity, Molecular Cell, vol.6, issue.3, pp.539-550, 2000. ,
DOI : 10.1016/S1097-2765(00)00053-8
Epithelial calcineurin controls microbiota-dependent intestinal tumor development, Nature Medicine, vol.503, issue.5, pp.506-515, 2016. ,
DOI : 10.1111/j.1654-1103.2003.tb02228.x
Cutting Edge: Atypical PKCs Regulate T Lymphocyte Polarity and Scanning Behavior, The Journal of Immunology, vol.179, issue.9, pp.5649-5652, 2007. ,
DOI : 10.4049/jimmunol.179.9.5649
Organization and execution of the epithelial polarity programme, Nature Reviews Molecular Cell Biology, vol.229, issue.4, pp.225-242, 2014. ,
DOI : 10.1002/dvdy.10458
Scaffold protein Dlgh1 coordinates alternative p38 kinase activation, directing T cell receptor signals toward NFAT but not NF-??B transcription factors, Nature Immunology, vol.22, issue.2, pp.154-161, 2007. ,
DOI : 10.1084/jem.20030976
Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces, Immunity, vol.28, issue.4, pp.546-558, 2008. ,
DOI : 10.1016/j.immuni.2008.02.017
Tpl2 ablation promotes intestinal inflammation and tumorigenesis in Apcmin mice by inhibiting IL-10 secretion and regulatory T-cell generation, Proc. Natl. Acad. Sci. USA, pp.1082-1091, 2012. ,
DOI : 10.1084/jem.20091059
Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex, Proc. Natl. Acad. Sci. USA, pp.11381-11386, 2011. ,
DOI : 10.1074/jbc.M304838200
Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4, Nature, vol.382, issue.6589, pp.370-373, 1996. ,
DOI : 10.1038/382370a0
Stimulated nuclear translocation of NF-kappaB and shuttling differentially depend on dynein and the dynactin complex, Proc. Natl. Acad. Sci. USA, pp.2647-2652, 2009. ,
Orchestrating cytoskeleton and intracellular vesicle traffic to build functional immunological synapses, Immunological Reviews, vol.3, issue.1, pp.118-132, 2013. ,
DOI : 10.3390/v3091757
URL : https://hal.archives-ouvertes.fr/pasteur-01371059
The ??-Catenin Destruction Complex, Cold Spring Harbor Perspectives in Biology, vol.5, issue.1, p.7898, 2013. ,
DOI : 10.1101/cshperspect.a007898
Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene, Science, vol.256, issue.5057, pp.668-670, 1992. ,
DOI : 10.1126/science.1350108
Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer, Nature Immunology, vol.85, issue.2, pp.194-202, 2008. ,
DOI : 10.4049/jimmunol.178.7.4022
Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells, Proc. Natl. Acad. Sci. USA, pp.16258-16263, 2012. ,
DOI : 10.1084/jem.20072484
Transcriptional Control of Regulatory T-Cell Differentiation, Cold Spring Harbor Symposia on Quantitative Biology, vol.78, issue.0, pp.215-222, 2013. ,
DOI : 10.1101/sqb.2013.78.020289
Importins and Beyond: Non-Conventional Nuclear Transport Mechanisms, Traffic, vol.18, issue.9, pp.1188-1198, 2009. ,
DOI : 10.1016/j.bbagen.2004.03.015
FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT, Cell, vol.126, issue.2, pp.375-387, 2006. ,
DOI : 10.1016/j.cell.2006.05.042
Discs large (Dlg1) complexes in lymphocyte activation, The Journal of Cell Biology, vol.15, issue.2, pp.173-178, 2004. ,
DOI : 10.1128/MCB.15.8.4337
Foxp3+ T cells expressing ROR??t represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation, Mucosal Immunology, vol.381, issue.2, pp.444-457, 2016. ,
DOI : 10.1093/nar/gkn838
Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76, Nature Immunology, vol.235, issue.12, pp.1253-1262, 2005. ,
DOI : 10.4049/jimmunol.171.3.1360
More than two decades of Apc modeling in rodents, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, vol.1836, issue.1, pp.80-89, 2013. ,
DOI : 10.1016/j.bbcan.2013.01.001
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate, Nature, vol.204, issue.7282, pp.808-812, 2010. ,
DOI : 10.4049/jimmunol.170.7.3724
Immunoglobulin E Signal Inhibition during Allergen Ingestion Leads to Reversal of Established Food Allergy and Induction of Regulatory T Cells, Immunity, vol.41, issue.1, pp.141-151, 2014. ,
DOI : 10.1016/j.immuni.2014.05.017
A novel pathway down-modulating T cell activation involves HPK-1???dependent recruitment of 14-3-3 proteins on SLP-76, The Journal of Experimental Medicine, vol.15, issue.3, pp.681-691, 2007. ,
DOI : 10.1074/jbc.272.15.9979
URL : https://hal.archives-ouvertes.fr/pasteur-01372621
Parathyroid hormone responses of cyclic AMP-, serum- and phorbol ester-responsive reporter genes in osteoblast-like UMR-106 cells, Molecular and Cellular Endocrinology, vol.139, issue.1-2, pp.89-98, 1998. ,
DOI : 10.1016/S0303-7207(98)00070-7
Photochemically generated cytosolic calcium pulses and their detection by fluo-3, J Biol Chem, vol.264, pp.8179-8184, 1989. ,
Ezrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse, The EMBO Journal, vol.161, issue.14, pp.2301-2314, 2010. ,
DOI : 10.1038/ni1272
URL : https://hal.archives-ouvertes.fr/pasteur-00593159
Release of serine/threonine-phosphorylated adaptors from signaling microclusters down-regulates T cell activation, The Journal of Cell Biology, vol.195, issue.5, pp.839-853, 2011. ,
DOI : 10.1038/ni1272
URL : https://hal.archives-ouvertes.fr/pasteur-00646203
Isolation of Mouse Small Intestinal Intraepithelial Lymphocytes, Peyer's Patch, and Lamina Propria Cells, Curr Protoc Immunol Chapter, vol.155, p.19, 2001. ,
DOI : 10.1002/0471142735.im0319s17
The Membrane-Microfilament Linker Ezrin Is Involved in the Formation of the Immunological Synapse and in T Cell Activation, Immunity, vol.15, issue.5, pp.715-728, 2001. ,
DOI : 10.1016/S1074-7613(01)00225-4
URL : https://hal.archives-ouvertes.fr/hal-00161327