M. Lehrke, G. Pascual, C. Glass, and M. Lazar, Gaining weight: the Keystone Symposium on PPAR and LXR, Genes & Development, vol.19, issue.15, pp.1737-1742, 2005.
DOI : 10.1101/gad.1341005

URL : http://genesdev.cshlp.org/content/19/15/1737.full.pdf

T. Iwanaga, R. Tsutsumi, J. Noritake, Y. Fukata, and M. Fukata, Dynamic protein palmitoylation in cellular signaling, Progress in Lipid Research, vol.48, issue.3-4, pp.117-127, 2009.
DOI : 10.1016/j.plipres.2009.02.001

R. Brookheart, C. Michel, and J. Schaffer, As a Matter of Fat, Cell Metabolism, vol.10, issue.1, pp.9-12, 2009.
DOI : 10.1016/j.cmet.2009.03.011

J. Menendez and R. Lupu, Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis, Nature Reviews Cancer, vol.280, issue.10, pp.763-777, 2007.
DOI : 10.4161/auto.3269

J. Menendez, A. Vazquez-martin, F. Ortega, and J. Fernandez-real, Fatty Acid Synthase: Association with Insulin Resistance, Type 2 Diabetes, and Cancer, Clinical Chemistry, vol.55, issue.3, pp.425-438, 2009.
DOI : 10.1373/clinchem.2008.115352

URL : http://clinchem.aaccjnls.org/content/clinchem/55/3/425.full.pdf

P. Denechaud, J. Girard, and C. Postic, Carbohydrate responsive element binding protein and lipid homeostasis, Current Opinion in Lipidology, vol.19, issue.3, pp.301-306, 2008.
DOI : 10.1097/MOL.0b013e3282ffafaa

M. Lafontan and D. Langin, Lipolysis and lipid mobilization in human adipose tissue, Progress in Lipid Research, vol.48, issue.5, pp.275-297, 2009.
DOI : 10.1016/j.plipres.2009.05.001

URL : https://hal.archives-ouvertes.fr/inserm-00410140

R. Zechner, P. Kienesberger, G. Haemmerle, R. Zimmermann, and A. Lass, Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores, Journal of Lipid Research, vol.251, issue.1, pp.3-21, 2009.
DOI : 10.2174/1381612054546914

C. Nagle, E. Klett, and R. Coleman, Hepatic triacylglycerol accumulation and insulin resistance, Journal of Lipid Research, vol.10, issue.Supplement, pp.74-79, 2009.
DOI : 10.2337/db06-1619

URL : http://www.jlr.org/content/50/Supplement/S74.full.pdf

K. Baker and C. Thummel, Diabetic Larvae and Obese Flies???Emerging Studies of Metabolism in Drosophila, Cell Metabolism, vol.6, issue.4, pp.257-266, 2007.
DOI : 10.1016/j.cmet.2007.09.002

M. Sieber and C. Thummel, The DHR96 Nuclear Receptor Controls Triacylglycerol Homeostasis in Drosophila, Cell Metabolism, vol.10, issue.6, pp.481-490, 2009.
DOI : 10.1016/j.cmet.2009.10.010

V. Wigglesworth, The utilization of reserve substances in Drosophila during flight, J Exp Biol, vol.26, pp.150-163, 1949.

A. Ruaud, G. Lam, and C. Thummel, NR4A Nuclear Receptor DHR38 Regulates Carbohydrate Metabolism and Glycogen Storage, Molecular Endocrinology, vol.25, issue.1, pp.83-91, 2011.
DOI : 10.1210/me.2010-0337

URL : https://academic.oup.com/mend/article-pdf/25/1/83/10721661/mend0083.pdf

E. Gutierrez, D. Wiggins, B. Fielding, and A. Gould, Specialized hepatocyte-like cells regulate Drosophila lipid metabolism, Nature, vol.84, issue.7125, pp.275-280, 2007.
DOI : 10.1042/bj2550929

W. Wheeler, Concerning the ???Blood-Tissue??? of the Insecta.???I, Psyche: A Journal of Entomology, vol.6, issue.190, pp.233-236, 1892.
DOI : 10.1155/1892/54147

G. Manning and M. Krasnow, Development of the Drosophila tracheal system, Cold Spring Harbor, 1993.

M. Barber, N. Price, and M. Travers, Structure and regulation of acetyl-CoA carboxylase genes of metazoa, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol.1733, issue.1, pp.1-28, 2005.
DOI : 10.1016/j.bbalip.2004.12.001

S. Smith and S. Tsai, The type I fatty acid and polyketide synthases: a tale of two megasynthases, Natural Product Reports, vol.146, issue.144, pp.1041-1072, 2007.
DOI : 10.1016/S0969-2126(02)00716-5

A. Jakobsson, R. Westerberg, and A. Jacobsson, Fatty acid elongases in mammals: Their regulation and roles in metabolism, Progress in Lipid Research, vol.45, issue.3, pp.237-249, 2006.
DOI : 10.1016/j.plipres.2006.01.004

H. Guillou, D. Zadravec, P. Martin, and A. Jacobsson, The key roles of elongases and desaturases in mammalian fatty acid metabolism: Insights from transgenic mice, Progress in Lipid Research, vol.49, issue.2, pp.186-199, 2010.
DOI : 10.1016/j.plipres.2009.12.002

L. Abu-elheiga, M. Matzuk, P. Kordari, W. Oh, and T. Shaikenov, Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal, Proceedings of the National Academy of Sciences, vol.100, issue.13, pp.12011-12016, 2005.
DOI : 10.1073/pnas.1332670100

URL : http://www.pnas.org/content/102/34/12011.full.pdf

L. Abu-elheiga, M. Matzuk, K. Abo-hashema, and S. Wakil, Continuous Fatty Acid Oxidation and Reduced Fat Storage in Mice Lacking Acetyl-CoA Carboxylase 2, Science, vol.291, issue.5513, pp.2613-2616, 2001.
DOI : 10.1126/science.1056843

M. Morillas, P. Gomez-puertas, R. Roca, D. Serra, and G. Asins, Structural Model of the Catalytic Core of Carnitine Palmitoyltransferase I and Carnitine Octanoyltransferase (COT), Journal of Biological Chemistry, vol.42, issue.48, pp.45001-45008, 2001.
DOI : 10.1002/prot.340090107

J. Mao, F. Demayo, H. Li, L. Abu-elheiga, and Z. Gu, Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis, Proceedings of the National Academy of Sciences, vol.44, issue.10, pp.8552-8557, 2006.
DOI : 10.1194/jlr.M300094-JLR200

J. Mao, T. Yang, Z. Gu, W. Heird, and M. Finegold, aP2-Cre-mediated inactivation of acetyl-CoA carboxylase 1 causes growth retardation and reduced lipid accumulation in adipose tissues, Proceedings of the National Academy of Sciences, vol.26, issue.3, pp.17576-17581, 2009.
DOI : 10.1128/MCB.26.3.1063-1076.2006

S. Chirala, H. Chang, M. Matzuk, L. Abu-elheiga, and J. Mao, Fatty acid synthesis is essential in embryonic development: Fatty acid synthase null mutants and most of the heterozygotes die in utero, Proceedings of the National Academy of Sciences, vol.99, issue.14, pp.6358-6363, 2003.
DOI : 10.1073/pnas.152327099

M. Chakravarthy, Z. Pan, Y. Zhu, K. Tordjman, and J. Schneider, ???New??? hepatic fat activates PPAR?? to maintain glucose, lipid, and cholesterol homeostasis, Cell Metabolism, vol.1, issue.5, pp.309-322, 2005.
DOI : 10.1016/j.cmet.2005.04.002

URL : https://doi.org/10.1016/j.cmet.2005.04.002

G. Dietzl, D. Chen, F. Schnorrer, K. Su, and Y. Barinova, A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila, Nature, vol.39, issue.7150, pp.151-156, 2007.
DOI : 10.1038/nature05954

. Flybase, The FlyBase database of the Drosophila genome projects and community literature, Nucleic Acids Res, vol.31, pp.172-175, 2003.

V. Chintapalli, J. Wang, and J. Dow, Using FlyAtlas to identify better Drosophila melanogaster models of human disease, Nature Genetics, vol.38, issue.6, pp.715-720, 2007.
DOI : 10.1152/physrev.00035.2002

E. Parra-peralbo and J. Culi, Drosophila lipophorin receptors mediate the uptake of neutral lipids in oocytes and imaginal disc cells by an endocytosisindependent mechanism, PLoS Genet, vol.7, 2011.

J. Wingrove, O. Farrell, and P. , Nitric Oxide Contributes to Behavioral, Cellular, and Developmental Responses to Low Oxygen in Drosophila, Cell, vol.98, issue.1, pp.105-114, 1999.
DOI : 10.1016/S0092-8674(00)80610-8

J. Billeter, J. Atallah, J. Krupp, J. Millar, and J. Levine, Specialized cells tag sexual and species identity in Drosophila melanogaster, Nature, vol.95, issue.7266, pp.987-991, 2009.
DOI : 10.1038/nature08495

J. Reiling and E. Hafen, The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila, Genes & Development, vol.18, issue.23, pp.2879-2892, 2004.
DOI : 10.1101/gad.322704

M. Rizki, The cytophysiology of the spiracular glands of Drosophila melanogaster, Journal of Morphology, vol.134, issue.3, pp.497-511, 1956.
DOI : 10.3109/10520294409105827

M. Jarial and E. Engstrom, Fine structure of the spiracular glands in larval Drosophila melanogaster (Meig.) (Diptera : Drosophilidae), International Journal of Insect Morphology and Embryology, vol.24, issue.1, pp.1-12, 1995.
DOI : 10.1016/0020-7322(94)00010-N

N. Dantuma, M. Potters, D. Winther, M. Tensen, C. Kooiman et al., An insect homolog of the vertebrate very low density lipoprotein receptor mediates endocytosis of lipophorins, J Lipid Res, vol.40, pp.973-978, 1999.

M. Qatanani and M. Lazar, Mechanisms of obesity-associated insulin resistance: many choices on the menu, Genes & Development, vol.21, issue.12, pp.1443-1455, 2007.
DOI : 10.1101/gad.1550907

L. Agius, Glucokinase and molecular aspects of liver glycogen metabolism, Biochemical Journal, vol.414, issue.1, pp.1-18, 2008.
DOI : 10.1042/BJ20080595

URL : http://www.biochemj.org/content/ppbiochemj/414/1/1.full.pdf

M. Krssak, A. Brehm, E. Bernroider, C. Anderwald, and P. Nowotny, Alterations in Postprandial Hepatic Glycogen Metabolism in Type 2 Diabetes, Diabetes, vol.53, issue.12, pp.3048-3056, 2004.
DOI : 10.2337/diabetes.53.12.3048

S. Kir, S. Beddow, V. Samuel, P. Miller, and S. Previs, FGF19 as a Postprandial, Insulin-Independent Activator of Hepatic Protein and Glycogen Synthesis, Science, vol.116, issue.1, pp.1621-1624, 2011.
DOI : 10.1172/JCI25735

T. Docsa, K. Czifrak, C. Huse, L. Somsak, and P. Gergely, Effect of glucopyranosylidene-spiro-thiohydantoin on glycogen metabolism in liver tissues of streptozotocin-induced and obese diabetic rats, Mol Med Report, vol.4, pp.477-481, 2011.

D. Cross, D. Alessi, P. Cohen, M. Andjelkovich, and B. Hemmings, Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B, Nature, vol.270, issue.6559, pp.785-789, 1995.
DOI : 10.1128/MCB.15.4.2304

D. Sutherland, C. Samakovlis, and M. Krasnow, branchless Encodes a Drosophila FGF Homolog That Controls Tracheal Cell Migration and the Pattern of Branching, Cell, vol.87, issue.6, pp.1091-1101, 1996.
DOI : 10.1016/S0092-8674(00)81803-6

T. Gryzik and H. Muller, FGF8-like1 and FGF8-like2 Encode Putative Ligands of the FGF Receptor Htl and Are Required for Mesoderm Migration in the Drosophila Gastrula, Current Biology, vol.14, issue.8, pp.659-667, 2004.
DOI : 10.1016/j.cub.2004.03.058

H. Albro, A cytological study of the changes occurring in the oenocytes of Galerucella nymphaeae Linn. during the larval and pupal periods of development, Journal of Morphology, vol.43, issue.2, pp.527-567, 1930.
DOI : 10.1002/jmor.1050500211

J. Pospisilik, D. Schramek, H. Schnidar, S. Cronin, and N. Nehme, Drosophila Genome-wide Obesity Screen Reveals Hedgehog as a Determinant of Brown versus White Adipose Cell Fate, Cell, vol.140, issue.1, pp.148-160, 2010.
DOI : 10.1016/j.cell.2009.12.027

E. Kraegen, G. Cooney, and N. Turner, Muscle insulin resistance: A case of fat overconsumption, not mitochondrial dysfunction, Proceedings of the National Academy of Sciences, vol.57, issue.5, pp.7627-7628, 2008.
DOI : 10.2337/db07-1556

J. Browning, J. Baxter, S. Satapati, and S. Burgess, The effect of short-term fasting on liver and skeletal muscle lipid, glucose, and energy metabolism in healthy women and men, Journal of Lipid Research, vol.41, issue.3, pp.577-586, 2012.
DOI : 10.2337/db09-1625

G. Martins, J. Ramalho-ortigao, N. Lobo, D. Severson, and M. Mcdowell, Insights into the transcriptome of oenocytes from Aedes aegypti pupae, Mem??rias do Instituto Oswaldo Cruz, vol.20, issue.3, pp.308-315, 2011.
DOI : 10.1016/0040-8166(88)90033-X

J. Krupp, C. Kent, J. Billeter, R. Azanchi, and A. So, Social Experience Modifies Pheromone Expression and Mating Behavior in Male Drosophila melanogaster, Current Biology, vol.18, issue.18, pp.1373-1383, 2008.
DOI : 10.1016/j.cub.2008.07.089

URL : https://doi.org/10.1016/j.cub.2008.09.038

K. Kohler, E. Brunner, X. Guan, K. Boucke, and U. Greber, A combined proteomic and genetic analysis identifies a role for the lipid desaturase Desat1 in starvation-induced autophagy in Drosophila, Autophagy, vol.5, issue.7, pp.980-990, 2009.
DOI : 10.4161/auto.5.7.9325

V. Wigglesworth, The source of lipids and polyphenols for the insect cuticle: The role of fat body, oenocytes and oenocytoids, Tissue and Cell, vol.20, issue.6, pp.919-932, 1988.
DOI : 10.1016/0040-8166(88)90033-X

Y. Li and Y. Paik, A potential role for fatty acid biosynthesis genes during molting and cuticle formation in Caenorhabditis elegans, BMB Reports, vol.44, issue.4, pp.285-290, 2011.
DOI : 10.5483/BMBRep.2011.44.4.285

A. Hoffmann and L. Harshman, Desiccation and starvation resistance in Drosophila: patterns of variation at the species, population and intrapopulation levels, Heredity, vol.49, issue.6, pp.637-643, 1999.
DOI : 10.1111/j.1558-5646.1995.tb02301.x

L. Neven and E. Mitcham, Controlled atmosphere technologies for insect control Encyclopedia of entomology, pp.1046-1051, 2008.

L. Liu, W. Johnson, and M. Welsh, Drosophila DEG/ENaC pickpocket genes are expressed in the tracheal system, where they may be involved in liquid clearance, Proceedings of the National Academy of Sciences, vol.21, issue.6, pp.2128-2133, 2003.
DOI : 10.1016/S0896-6273(00)80661-3

M. Behr, C. Wingen, C. Wolf, R. Schuh, and M. Hoch, Wurst is essential for airway clearance and respiratory-tube size control, Nature Cell Biology, vol.108, issue.7, pp.847-853, 2007.
DOI : 10.1038/ng0396-325

L. Zhang and W. Ret, uninflatable encodes a novel ectodermal apical surface protein required for tracheal inflation in Drosophila, Developmental Biology, vol.336, issue.2, pp.201-212, 2009.
DOI : 10.1016/j.ydbio.2009.09.040

D. Alvarez-de-la-rosa, C. Canessa, G. Fyfe, and P. Zhang, Structure and Regulation of Amiloride-Sensitive Sodium Channels, Annual Review of Physiology, vol.62, issue.1, pp.573-594, 2000.
DOI : 10.1146/annurev.physiol.62.1.573

E. Hummler, P. Barker, J. Gatzy, F. Beermann, and C. Verdumo, Early death due to defective neonatal lung liquid clearance in ??ENaC-deficient mice, Nature Genetics, vol.13, issue.3, pp.325-328, 1996.
DOI : 10.1016/0925-4773(93)90098-I

J. M. Whitten, T. R. Ashburner, and . Wright, The tracheal system, pp.499-540, 1980.

H. Asha, I. Nagy, G. Kovacs, D. Stetson, and I. Ando, Analysis of Rasinduced overproliferation in Drosophila hemocytes, Genetics, vol.163, pp.203-215, 2003.

P. Chen, W. Nordstrom, B. Gish, and J. Abrams, grim, a novel cell death gene in Drosophila., Genes & Development, vol.10, issue.14, pp.1773-1782, 1996.
DOI : 10.1101/gad.10.14.1773

A. Parks, K. Cook, M. Belvin, N. Dompe, and R. Fawcett, Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome, Nature Genetics, vol.87, issue.3, pp.288-292, 2004.
DOI : 10.1073/pnas.87.8.3170

X. Ye and Q. Liu, Expression, Purification, and Analysis of Recombinant Drosophila Dicer-1 and Dicer-2 Enzymes, Methods Mol Biol, vol.442, pp.11-27, 2008.
DOI : 10.1007/978-1-59745-191-8_2

Y. Lee and R. Carthew, Making a better RNAi vector for Drosophila: use of intron spacers, Methods, vol.30, pp.322-329, 2003.

Y. Romeo and B. Lemaitre, Drosophila Immunity, Methods Mol Biol, vol.415, pp.379-394, 2008.
DOI : 10.1007/978-1-59745-570-1_22

URL : https://hal.archives-ouvertes.fr/hal-00133466

N. Meunier, Y. Belgacem, and J. Martin, Regulation of feeding behaviour and locomotor activity by takeout in Drosophila, Journal of Experimental Biology, vol.210, issue.8, pp.1424-1434, 2007.
DOI : 10.1242/jeb.02755

URL : https://hal.archives-ouvertes.fr/hal-00140074

M. Dionne, L. Pham, M. Shirasu-hiza, and D. Schneider, Akt and foxo Dysregulation Contribute to Infection-Induced Wasting in Drosophila, Current Biology, vol.16, issue.20, pp.1977-1985, 2006.
DOI : 10.1016/j.cub.2006.08.052

URL : https://doi.org/10.1016/j.cub.2006.08.052

C. Bathellier, G. Tcherkez, C. Mauve, R. Bligny, and E. Gout, On the resilience of nitrogen assimilation by intact roots under starvation, as revealed by isotopic and metabolomic techniques, Rapid Communications in Mass Spectrometry, vol.22, issue.18, pp.2847-2856, 2009.
DOI : 10.1111/j.1399-3054.1989.tb06213.x

URL : https://hal.archives-ouvertes.fr/hal-00422543