Ensembl 2008

P. Flicek , B. Aken , K. Beal , Benoit Ballester (1) , M. Caccamo , Y. Chen , L. Clarke , G. Coates , F. Cunningham , T. Cutts , T. Down , S. Dyer , T. Eyre , S. Fitzgerald , J. Fernandez-Banet , S. Gräf , S. Haider , M. Hammond , R. Holland (2) , K. Howe , N. Johnson , A. Jenkinson , A. Kähäri , D. Keefe , F. Kokocinski , E. Kulesha , D. Lawson , I. Longden , K. Megy , P. Meidl , B. Overduin , A. Parker , B. Pritchard , A. Prlic , S. Rice , D. Rios (3) , M. Schuster (4) , I. Sealy , G. Slater , D. Smedley , G. Spudich , S. Trevanion , A. Vilella , J. Vogel , S. White , M. Wood , E. Birney , T. Cox , V. Curwen , R. Durbin , X. M. Fernandez-Suarez , J. Herrero (5) , J. Hubbard , A. Kasprzyk , G. Proctor , J. Smith , A. Ureta-Vidal , S. Searle , S. Graf , A. Kahari

1 TAGC - Technologies avancées pour le génôme et la clinique
2 National Expert and Training Centre for Breast Cancer Screening
3 TIMA - Techniques de l'Informatique et de la Microélectronique pour l'Architecture des systèmes intégrés
4 IPGS - Institut de physique du globe de Strasbourg
5 Dep. of Energy

The Ensembl project (http://www.ensembl.org) is a comprehensive genome information system featuring an integrated set of genome annotation, databases and other information for chordate and selected model organism and disease vector genomes. As of release 47 (October 2007), Ensembl fully supports 35 species, with preliminary support for six additional species. New species in the past year include platypus and horse. Major additions and improvements to Ensembl since our previous report include extensive support for functional genomics data in the form of a specialized functional genomics database, genome-wide maps of protein–DNA interactions and the Ensembl regulatory build; support for customization of the Ensembl web interface through the addition of user accounts and user groups; and increased support for genome resequencing. We have also introduced new comparative genomics-based data mining options and report on the continued development of our software infrastructure.

Domaines: Bio-informatique [q-bio.QM]

P. Flicek, B. Aken, K. Beal, Benoit Ballester, M. Caccamo, et al.. Ensembl 2008. Nucleic Acids Research, 2007, 36 (Database), pp.D707 - D714. ⟨10.1093/nar/gkm988⟩. ⟨hal-01626053⟩