R. P. Aaronson and G. Blobel, Isolation of nuclear pore complexes in association with a lamina., Proceedings of the National Academy of Sciences, vol.72, issue.3, pp.1007-1011, 1975.
DOI : 10.1073/pnas.72.3.1007

U. Aebi, J. Cohn, L. Buhle, and L. Gerace, The nuclear lamina is a meshwork of intermediate-type filaments, Nature, vol.151, issue.6088, pp.560-564, 1038.
DOI : 10.1242/jcs.1984.Supplement_1.10

A. K. Agarwal, J. P. Fryns, R. J. Auchus, and A. Garg, Zinc metalloproteinase, ZMPSTE24, is mutated in mandibuloacral dysplasia, Human Molecular Genetics, vol.12, issue.16, 1995.
DOI : 10.1093/hmg/ddg213
URL : https://academic.oup.com/hmg/article-pdf/12/16/1995/6947753/ddg213.pdf

R. C. Allsopp, H. Vaziri, C. Patterson, S. Goldstein, E. V. Younglai et al., Telomere length predicts replicative capacity of human fibroblasts., Proceedings of the National Academy of Sciences, vol.89, issue.21, pp.10114-10118, 1992.
DOI : 10.1073/pnas.89.21.10114

M. Y. Armanios, J. J. Chen, J. D. Cogan, J. K. Alder, R. G. Ingersoll et al., Telomerase Mutations in Families with Idiopathic Pulmonary Fibrosis, New England Journal of Medicine, vol.356, issue.13, pp.1317-1326, 1056.
DOI : 10.1056/NEJMoa066157

N. Arnoult, C. Schluth-bolard, A. Letessier, I. Drascovic, R. Bouarich-bourimi et al., Replication Timing of Human Telomeres Is Chromosome Arm???Specific, Influenced by Subtelomeric Structures and Connected to Nuclear Localization, PLoS Genetics, vol.67, issue.9, 2010.
DOI : 10.1371/journal.pgen.1000920.s002
URL : https://hal.archives-ouvertes.fr/ensl-00815144

B. C. Ballif, S. G. Sulpizio, R. M. Lloyd, S. L. Minier, A. Theisen et al., The clinical utility of enhanced subtelomeric coverage in array CGH, American Journal of Medical Genetics Part A, vol.76, issue.16, pp.1850-1857, 2007.
DOI : 10.1038/labinvest.3780394

G. Banumathy, N. Somaiah, R. Zhang, Y. Tang, J. Hoffmann et al., Human UBN1 Is an Ortholog of Yeast Hpc2p and Has an Essential Role in the HIRA/ASF1a Chromatin-Remodeling Pathway in Senescent Cells, Molecular and Cellular Biology, vol.29, issue.3, pp.758-770, 1128.
DOI : 10.1128/MCB.01047-08

F. Barthelemy, C. Navarro, R. Fayek, D. Silva, N. Roll et al., Truncated prelamin A expression in HGPS-like patients: a transcriptional study, European Journal of Human Genetics, vol.23, issue.8, pp.1051-1061, 2015.
DOI : 10.1126/scitranslmed.3002847
URL : https://hal.archives-ouvertes.fr/hal-01597886

J. A. Baur, Y. Zou, J. W. Shay, W. , and W. E. , Telomere Position Effect in Human Cells, Science, vol.292, issue.5524, pp.2075-2077, 2001.
DOI : 10.1126/science.1062329

R. Ben-yishay, A. J. Ashkenazy, and Y. Shav-tal, Dynamic Encounters of Genes and Transcripts with the Nuclear Pore, Trends in Genetics, vol.32, issue.7, pp.419-431, 2016.
DOI : 10.1016/j.tig.2016.04.003

B. Pfleghaar, K. Taimen, P. Butin-israeli, V. Shimi, T. Langer-freitag et al., Gene-rich chromosomal regions are preferentially localized in the lamin B deficient nuclear blebs of atypical progeria cells, Nucleus, vol.105, issue.1, pp.66-76, 1080.
DOI : 10.1023/A:1026799818566

G. Blobel, Gene gating: a hypothesis., Proceedings of the National Academy of Sciences, vol.82, issue.24, 1985.
DOI : 10.1073/pnas.82.24.8527
URL : http://www.pnas.org/content/82/24/8527.full.pdf

T. Boulikas, Protein???protein and protein???DNA interactions in calf thymus nuclear matrix using cross-linking by ultraviolet irradiation, Biochemistry and Cell Biology, vol.64, issue.5, pp.474-484, 1986.
DOI : 10.1139/o86-066

D. Bouvier, J. Hubert, A. P. Seve, and M. Bouteille, Characterization of lamina-bound chromatin in the nuclear shell isolated from HeLa cells, Experimental Cell Research, vol.156, issue.2, pp.500-512, 1985.
DOI : 10.1016/0014-4827(85)90557-9

S. Boyle, S. Gilchrist, J. M. Bridger, N. L. Mahy, J. A. Ellis et al., The spatial organization of human chromosomes within the nuclei of normal and emerin-mutant cells, Human Molecular Genetics, vol.10, issue.3, pp.211-219, 2001.
DOI : 10.1093/hmg/10.3.211

A. P. Bracken, D. Kleine-kohlbrecher, N. Dietrich, D. Pasini, G. Gargiulo et al., The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells, Genes & Development, vol.21, issue.5, pp.525-530, 2007.
DOI : 10.1101/gad.415507

M. R. Branco and A. Pombo, Intermingling of Chromosome Territories in Interphase Suggests Role in Translocations and Transcription-Dependent Associations, PLoS Biology, vol.47, issue.5, 2006.
DOI : 10.1371/journal.pbio.0040138.st001

A. Brussino, G. Vaula, C. Cagnoli, E. Panza, M. Seri et al., A family with autosomal dominant leukodystrophy linked to 5q23.2-q23.3 without lamin B1 mutations, European Journal of Neurology, vol.36, issue.4, pp.541-549, 2010.
DOI : 10.3174/ajnr.A1354

B. Burke and C. L. Stewart, Functional Architecture of the Cell's Nucleus in Development, Aging, and Disease, Curr. Top. Dev. Biol, vol.109, pp.1-52, 2014.
DOI : 10.1016/B978-0-12-397920-9.00006-8

V. Butin-israeli, S. A. Adam, and R. D. Goldman, Regulation of Nucleotide Excision Repair by Nuclear Lamin B1, PLoS ONE, vol.121, issue.7, 2013.
DOI : 10.1371/journal.pone.0069169.s004

M. Cai, Y. Huang, R. Ghirlando, K. L. Wilson, R. Craigie et al., Solution structure of the constant region of nuclear envelope protein LAP2 reveals two LEM-domain structures: one binds BAF and the other binds DNA, The EMBO Journal, vol.20, issue.16, pp.4399-4407, 2001.
DOI : 10.1093/emboj/20.16.4399

D. Camozzi, C. Capanni, V. Cenni, E. Mattioli, M. Columbaro et al., Diverse lamin-dependent mechanisms interact to control chromatin dynamics, Nucleus, vol.50, issue.5, pp.427-440, 2014.
DOI : 10.1101/gad.197954.112
URL : http://www.tandfonline.com/doi/pdf/10.4161/nucl.36289?needAccess=true

K. Cao, C. D. Blair, D. A. Faddah, J. E. Kieckhaefer, M. Olive et al., Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts, Journal of Clinical Investigation, vol.121, issue.7, pp.2833-2844, 1172.
DOI : 10.1172/JCI43578DS1
URL : http://www.jci.org/articles/view/43578/files/pdf

C. Capanni, V. Cenni, T. Haraguchi, S. Squarzoni, S. Schuchner et al., Lamin A precursor induces barrier-to-autointegration factor nuclear localization, Cell Cycle, vol.9, issue.13, pp.2600-2610, 2010.
DOI : 10.4161/cc.9.13.12080
URL : http://www.tandfonline.com/doi/pdf/10.4161/cc.9.13.12080?needAccess=true

C. Capanni, S. Squarzoni, V. Cenni, M. R. D-'apice, A. Gambineri et al., Familial partial lipodystrophy, mandibuloacral dysplasia and restrictive dermopathy feature barrier-to-autointegration factor (BAF) nuclear redistribution, Cell Cycle, vol.1, issue.19, pp.3568-3577, 2012.
DOI : 10.1091/mbc.E10-11-0928
URL : http://www.tandfonline.com/doi/pdf/10.4161/cc.21869?needAccess=true

P. Cau, C. Navarro, K. Harhouri, P. Roll, S. Sigaudy et al., Nuclear matrix, nuclear envelope and premature aging syndromes in a translational research perspective, Seminars in Cell & Developmental Biology, vol.29, pp.125-147, 2014.
DOI : 10.1016/j.semcdb.2014.03.021
URL : https://hal.archives-ouvertes.fr/hal-01646524

V. Cenni, C. Capanni, M. Columbaro, M. Ortolani, M. R. D-'apice et al., Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria, Eur. J. Histochem, 2011.

T. Chandra, P. A. Ewels, S. Schoenfelder, M. Furlan-magaril, S. W. Wingett et al., Global Reorganization of the Nuclear Landscape in Senescent Cells, Cell Reports, vol.10, issue.4, pp.471-483, 2015.
DOI : 10.1016/j.celrep.2014.12.055
URL : https://hal.archives-ouvertes.fr/hal-01464880

T. Chandra, K. Kirschner, J. Y. Thuret, B. D. Pope, T. Ryba et al., Independence of Repressive Histone Marks and Chromatin Compaction during Senescent Heterochromatic Layer Formation, Molecular Cell, vol.47, issue.2, pp.203-214, 2012.
DOI : 10.1016/j.molcel.2012.06.010

T. Chandra and M. Narita, High-order chromatin structure and the epigenome in SAHFs, Nucleus, vol.5, issue.1, pp.23-28, 2013.
DOI : 10.1126/science.1181369

B. Chen, L. A. Gilbert, B. A. Cimini, J. Schnitzbauer, W. Zhang et al., Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System, Cell, vol.155, issue.7, pp.1479-1491, 2013.
DOI : 10.1016/j.cell.2013.12.001

I. H. Chen, M. Huber, T. Guan, A. Bubeck, and L. Gerace, Nuclear envelope transmembrane proteins (NETs) that are up-regulated during myogenesis, BMC Cell Biology, vol.7, issue.1, pp.38-48, 2006.
DOI : 10.1186/1471-2121-7-38

A. Chojnowski, P. F. Ong, E. S. Wong, J. S. Lim, R. A. Mutalif et al., Progerin reduces LAP2alpha-telomere association in Hutchinson- Gilford progeria, pp.1-21, 2015.
DOI : 10.7554/elife.07759
URL : https://cdn.elifesciences.org/articles/07759/elife-07759-v2.pdf

C. H. Chuang, A. E. Carpenter, B. Fuchsova, T. Johnson, P. De-lanerolle et al., Long-Range Directional Movement of an Interphase Chromosome Site, Current Biology, vol.16, issue.8, pp.825-831, 2006.
DOI : 10.1016/j.cub.2006.03.059
URL : https://doi.org/10.1016/j.cub.2006.03.059

J. R. Chubb, S. Boyle, P. Perry, and W. A. Bickmore, Chromatin Motion Is Constrained by Association with Nuclear Compartments in Human Cells, Current Biology, vol.12, issue.6, pp.439-445, 2002.
DOI : 10.1016/S0960-9822(02)00695-4
URL : https://doi.org/10.1016/s0960-9822(02)00695-4

L. Crabbe, R. E. Verdun, C. I. Haggblom, and J. Karlseder, Defective Telomere Lagging Strand Synthesis in Cells Lacking WRN Helicase Activity, Science, vol.306, issue.5703, 1951.
DOI : 10.1126/science.1103619

T. Cremer and C. Cremer, Chromosome territories, nuclear architecture and gene regulation in mammalian cells, Nature Reviews Genetics, vol.2, issue.4, pp.292-301, 2001.
DOI : 10.1038/35066075

T. Cremer, C. Cremer, H. Baumann, E. K. Luedtke, K. Sperling et al., Rabl's model of the interphase chromosome arrangement tested in Chinise hamster cells by premature chromosome condensation and laser-UV-microbeam experiments, Human Genetics, vol.124, issue.1, pp.46-56, 1982.
DOI : 10.1007/BF00281263

J. A. Croft, J. M. Bridger, S. Boyle, P. Perry, P. Teague et al., Differences in the Localization and Morphology of Chromosomes in the Human Nucleus, The Journal of Cell Biology, vol.100, issue.6, pp.1119-1131, 1999.
DOI : 10.1023/A:1018438729203

D. L. Croteau, V. Popuri, P. L. Opresko, and V. A. Bohr, Human RecQ Helicases in DNA Repair, Recombination, and Replication, Annual Review of Biochemistry, vol.83, issue.1, pp.519-552, 2014.
DOI : 10.1146/annurev-biochem-060713-035428

L. Daniali, A. Benetos, E. Susser, J. D. Kark, C. Labat et al., Telomeres shorten at equivalent rates in somatic tissues of adults, Nature Communications, vol.5, 2013.
DOI : 10.1038/nprot.2010.124

A. Das, D. A. Grotsky, M. A. Neumann, R. Kreienkamp, I. Gonzalez-suarez et al., Lamin A ??exon9 mutation leads to telomere and chromatin defects but not genomic instability, Nucleus, vol.23, issue.5, pp.410-419, 2013.
DOI : 10.1038/ng1278
URL : http://www.tandfonline.com/doi/pdf/10.4161/nucl.26873?needAccess=true

D. Cecco, M. Criscione, S. W. Peckham, E. J. Hillenmeyer, S. Hamm et al., Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements, Aging Cell, vol.83, issue.2, pp.247-256, 2013.
DOI : 10.1016/j.lfs.2008.07.015

T. De-lange, Human telomeres are attached to the nuclear matrix, EMBO J, vol.11, pp.717-724, 1992.

D. Sandre-giovannoli, A. Bernard, R. Cau, P. Navarro, C. Amiel et al., Lamin A Truncation in Hutchinson-Gilford Progeria, Science, vol.300, issue.5628, 2003.
DOI : 10.1126/science.1084125

E. De-wit and W. De-laat, A decade of 3C technologies: insights into nuclear organization, Genes & Development, vol.26, issue.1, 2012.
DOI : 10.1101/gad.179804.111

T. Dechat, A. Gajewski, B. Korbei, D. Gerlich, N. Daigle et al., LAP2?? and BAF transiently localize to telomeres and specific regions on chromatin during nuclear assembly, Journal of Cell Science, vol.117, issue.25, pp.6117-6128, 2004.
DOI : 10.1242/jcs.01529
URL : http://jcs.biologists.org/content/joces/117/25/6117.full.pdf

T. Dechat, B. Korbei, O. A. Vaughan, S. Vlcek, C. J. Hutchison et al., Lamina-associated polypeptide 2alpha binds intranuclear A-type lamins, J. Cell Sci, vol.113, pp.3473-3484, 2000.

T. Dechat, K. Pfleghaar, K. Sengupta, T. Shimi, D. K. Shumaker et al., Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin, Genes & Development, vol.22, issue.7, pp.832-853, 2008.
DOI : 10.1101/gad.1652708

M. L. Decker, E. Chavez, I. Vulto, and P. M. Lansdorp, Telomere length in Hutchinson-Gilford Progeria Syndrome, Mechanisms of Ageing and Development, vol.130, issue.6, 2009.
DOI : 10.1016/j.mad.2009.03.001

J. Dekker, M. A. Marti-renom, L. A. Mirny, K. Rippe, M. Dekker et al., Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data, Nature Reviews Genetics, vol.8, issue.6, pp.390-403, 2002.
DOI : 10.1186/gb-2012-13-8-418

J. Demmerle, A. J. Koch, and J. M. Holaska, The Nuclear Envelope Protein Emerin Binds Directly to Histone Deacetylase 3 (HDAC3) and Activates HDAC3 Activity, Journal of Biological Chemistry, vol.114, issue.26, pp.22080-22088, 2012.
DOI : 10.1038/ng.297
URL : http://www.jbc.org/content/287/26/22080.full.pdf

D. Micco, R. Sulli, G. Dobreva, M. Liontos, M. Botrugno et al., Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer, Nature Cell Biology, vol.66, issue.3, pp.292-302, 2010.
DOI : 10.1002/cyto.a.20151

N. Dimitrova, Y. C. Chen, D. L. Spector, and T. De-lange, 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility, Nature, vol.151, issue.7221, pp.524-528, 1038.
DOI : 10.1038/nature07433

X. Ding, R. Xu, J. Yu, T. Xu, Y. Zhuang et al., SUN1 Is Required for Telomere Attachment to Nuclear Envelope and Gametogenesis in Mice, Developmental Cell, vol.12, issue.6, pp.863-872, 2007.
DOI : 10.1016/j.devcel.2007.03.018

J. R. Dixon, S. Selvaraj, F. Yue, A. Kim, Y. Li et al., Topological domains in mammalian genomes identified by analysis of chromatin interactions, Nature, vol.148, issue.7398, pp.376-380, 1038.
DOI : 10.1016/j.cell.2012.01.010

Y. Doksani, J. Y. Wu, T. De-lange, and X. Zhuang, Super-Resolution Fluorescence Imaging of Telomeres Reveals TRF2-Dependent T-loop Formation, Cell, vol.155, issue.2, pp.345-356, 2013.
DOI : 10.1016/j.cell.2013.09.048

D. Dorner, S. Vlcek, N. Foeger, A. Gajewski, C. Makolm et al., Lamina-associated polypeptide 2?? regulates cell cycle progression and differentiation via the retinoblastoma???E2F pathway, The Journal of Cell Biology, vol.9, issue.1, pp.83-93, 2006.
DOI : 10.1016/S0092-8674(04)00208-9

Y. Doubaj, A. De-sandre-giovannoli, E. V. Vera, C. L. Navarro, S. C. Elalaoui et al., An inherited LMNA gene mutation in atypical Progeria syndrome, Am. J. Med. Genet. A, vol.158, pp.2881-2887, 2012.

P. Edelmann, H. Bornfleth, D. Zink, T. Cremer, and C. Cremer, Morphology and dynamics of chromosome territories in living cells, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, vol.1551, issue.1, pp.29-39, 2001.
DOI : 10.1016/S0304-419X(01)00023-3

M. S. Eller, X. Liao, S. Liu, K. Hanna, H. Backvall et al., A role for WRN in telomere-based DNA damage responses, Proc. Natl. Acad, 2006.
DOI : 10.1038/sj.emboj.7600113

M. Eriksson, W. T. Brown, L. B. Gordon, M. W. Glynn, J. Singer et al., Recurrent de novo point mutations in lamin A cause Hutchinson???Gilford progeria syndrome, Nature, vol.66, issue.6937, pp.293-298, 1038.
DOI : 10.1086/302836

L. E. Finlan, D. Sproul, I. Thomson, S. Boyle, E. Kerr et al., Recruitment to the Nuclear Periphery Can Alter Expression of Genes in Human Cells, PLoS Genetics, vol.29, issue.3, 2008.
DOI : 10.1371/journal.pgen.1000039.s004

D. Z. Fisher, N. Chaudhary, and G. Blobel, cDNA sequencing of nuclear lamins A and C reveals primary and secondary structural homology to intermediate filament proteins., Proceedings of the National Academy of Sciences, vol.83, issue.17, pp.6450-6454, 1986.
DOI : 10.1073/pnas.83.17.6450

A. Freund, R. M. Laberge, M. Demaria, C. , and J. , Lamin B1 loss is a senescence-associated biomarker, Molecular Biology of the Cell, vol.23, issue.11, pp.2066-2075, 2012.
DOI : 10.1091/mbc.E11-10-0884
URL : http://www.molbiolcell.org/content/23/11/2066.full.pdf

K. Fukuchi, T. Katsuya, K. Sugimoto, M. Kuremura, H. D. Kim et al., LMNA mutation in a 45 year old Japanese subject with Hutchinson-Gilford progeria syndrome, Journal of Medical Genetics, vol.41, issue.5, p.14688, 2003.
DOI : 10.1136/jmg.2003.014688

M. J. Fullwood, M. H. Liu, Y. F. Pan, J. Liu, H. Xu et al., An oestrogen-receptor-??-bound human chromatin interactome, Nature, vol.283, issue.7269, pp.58-64, 2007.
DOI : 10.1038/nature08497
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774924/pdf

R. Funayama, M. Saito, H. Tanobe, and F. Ishikawa, Loss of linker histone H1 in cellular senescence, The Journal of Cell Biology, vol.87, issue.6, pp.869-880, 2006.
DOI : 10.1016/j.devcel.2004.10.019

D. Gerlich, J. Beaudouin, B. Kalbfuss, N. Daigle, R. Eils et al., Global Chromosome Positions Are Transmitted through Mitosis in Mammalian Cells, Cell, vol.112, issue.6, pp.751-764, 2003.
DOI : 10.1016/S0092-8674(03)00189-2
URL : https://doi.org/10.1016/s0092-8674(03)00189-2

K. Gesson, P. Rescheneder, M. P. Skoruppa, A. Von-haeseler, T. Dechat et al., A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha, Genome Research, vol.26, issue.4, pp.462-473115, 2016.
DOI : 10.1101/gr.196220.115

E. Giorgio, D. Robyr, M. Spielmann, E. Ferrero, D. Gregorio et al., A large genomic deletion leads to enhancer adoption by the lamin B1 gene: a second path to autosomal dominant adult-onset demyelinating leukodystrophy (ADLD), Human Molecular Genetics, vol.24, issue.11, pp.3143-3154, 2015.
DOI : 10.1093/hmg/ddv065

C. A. Glass, J. R. Glass, H. Taniura, K. W. Hasel, J. M. Blevitt et al., The alpha-helical rod domain of human lamins A and C contains a chromatin binding site, EMBO J, vol.12, pp.4413-4424, 1993.

M. Goldberg, A. Harel, M. Brandeis, T. Rechsteiner, T. J. Richmond et al., The tail domain of lamin Dm0 binds histones H2A and H2B, Proceedings of the National Academy of Sciences, vol.16, issue.6, pp.2852-2857, 1999.
DOI : 10.1128/MCB.16.6.2545

A. E. Goldman, G. Maul, P. M. Steinert, H. Y. Yang, and R. D. Goldman, Keratin-like proteins that coisolate with intermediate filaments of BHK-21 cells are nuclear lamins., Proceedings of the National Academy of Sciences, vol.83, issue.11, pp.3839-3843, 1986.
DOI : 10.1073/pnas.83.11.3839

R. D. Goldman, D. K. Shumaker, M. R. Erdos, M. Eriksson, A. E. Goldman et al., Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome, Proceedings of the National Academy of Sciences, vol.200, issue.3, pp.8963-8968, 2004.
DOI : 10.1016/0076-6879(91)00127-I

I. Gonzalez-suarez, A. B. Redwood, S. M. Perkins, B. Vermolen, D. Lichtensztejin et al., Novel roles for A-type lamins in telomere biology and the DNA damage response pathway, The EMBO Journal, vol.67, issue.16, pp.2414-2427, 0196.
DOI : 10.1073/pnas.94.14.7423

S. Gonzalo, DNA Damage and Lamins, Adv. Exp. Med. Biol, vol.773, pp.377-399, 2014.
DOI : 10.1007/978-1-4899-8032-8_17
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081481/pdf

S. Gonzalo and R. Kreienkamp, DNA repair defects and genome instability in Hutchinson???Gilford Progeria Syndrome, Current Opinion in Cell Biology, vol.34, 2015.
DOI : 10.1016/j.ceb.2015.05.007
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522337/pdf

I. Gotic and R. Foisner, Multiple novel functions of lamina associated polypeptide 2alpha in striated muscle, Nucleus, vol.1, 2010.

I. Gotic, M. Leschnik, U. Kolm, M. Markovic, B. J. Haubner et al., Lamina-Associated Polypeptide 2?? Loss Impairs Heart Function and Stress Response in Mice, Circulation Research, vol.106, issue.2, pp.346-353, 2010.
DOI : 10.1161/CIRCRESAHA.109.205724
URL : http://circres.ahajournals.org/content/circresaha/106/2/346.full.pdf

I. Gotic, W. M. Schmidt, K. Biadasiewicz, M. Leschnik, R. Spilka et al., Loss of LAP2?? Delays Satellite Cell Differentiation and Affects Postnatal Fiber-Type Determination, STEM CELLS, vol.29, issue.3, pp.480-488, 2010.
DOI : 10.1177/002215540004801110

M. Goto, R. W. Miller, Y. Ishikawa, and H. Sugano, Excess of rare cancers in Werner syndrome (adult progeria), Cancer Epidemiol. Biomarkers Prev, vol.5, pp.239-246, 1996.

Y. Gruenbaum and R. Foisner, Lamins: Nuclear Intermediate Filament Proteins with Fundamental Functions in Nuclear Mechanics and Genome Regulation, Annual Review of Biochemistry, vol.84, issue.1, pp.131-164, 2015.
DOI : 10.1146/annurev-biochem-060614-034115

L. Guelen, L. Pagie, E. Brasset, W. Meuleman, M. B. Faza et al., Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions Live fluorescence imaging reveals early recruitment of emerin, LBR, RanBP2, and Nup153 to reforming functional nuclear envelopes, Nature J. Cell Sci, vol.453, issue.113, pp.948-951, 2000.

T. Haraguchi, T. Koujin, M. Segura-totten, K. K. Lee, Y. Matsuoka et al., BAF is required for emerin assembly into the reforming nuclear envelope, J. Cell Sci, vol.114, pp.4575-4585, 2001.

J. C. Harr, T. R. Luperchio, X. Wong, E. Cohen, S. J. Wheelan et al., Directed targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins, The Journal of Cell Biology, vol.19, issue.1, pp.33-52, 2015.
DOI : 10.1016/j.cell.2012.04.035

N. S. Heiss, S. W. Knight, T. J. Vulliamy, S. M. Klauck, S. Wiemann et al., X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functions, Nature Genetics, vol.84, issue.1, pp.32-38, 1038.
DOI : 10.1016/0076-6879(93)18026-9

U. Herbig, M. Ferreira, L. Condel, D. Carey, and J. M. Sedivy, Cellular Senescence in Aging Primates, Science, vol.311, issue.5765, 2006.
DOI : 10.1126/science.1122446

P. Heun, T. Laroche, K. Shimada, P. Furrer, and S. M. Gasser, Chromosome Dynamics in the Yeast Interphase Nucleus, Science, vol.294, issue.5549, pp.2181-2186, 2001.
DOI : 10.1126/science.1065366

S. L. Hewitt, F. A. High, S. L. Reiner, A. G. Fisher, and M. Merkenschlager, Nuclear repositioning marks the selective exclusion of lineage-inappropriate transcription factor loci during T helper cell differentiation, European Journal of Immunology, vol.3, issue.12, pp.3604-3613, 2004.
DOI : 10.4049/jimmunol.168.3.1018

Y. Hirano, K. Hizume, H. Kimura, K. Takeyasu, T. Haraguchi et al., Lamin B Receptor Recognizes Specific Modifications of Histone H4 in Heterochromatin Formation, Journal of Biological Chemistry, vol.16, issue.51, pp.42654-42663, 2012.
DOI : 10.1073/pnas.85.22.8531

A. Ibarra and M. W. Hetzer, Nuclear pore proteins and the control of genome functions, Genes & Development, vol.29, issue.4, 2015.
DOI : 10.1101/gad.256495.114

J. Ibn-salem, S. Kohler, M. I. Love, H. R. Chung, N. Huang et al., Deletions of chromosomal regulatory boundaries are associated with congenital disease, Genome Biology, vol.42, issue.9, pp.423-433, 2014.
DOI : 10.1093/nar/gkt1168

M. Jeanblanc, S. Ragu, C. Gey, K. Contrepois, R. Courbeyrette et al., Parallel pathways in RAF-induced senescence and conditions for its reversion, Oncogene, vol.62, issue.25, pp.3072-3085481, 2011.
DOI : 10.1101/gad.12.19.2997

J. C. Jeyapalan, M. Ferreira, J. M. Sedivy, and U. Herbig, Accumulation of senescent cells in mitotic tissue of aging primates, Mechanisms of Ageing and Development, vol.128, issue.1, pp.36-44, 2007.
DOI : 10.1016/j.mad.2006.11.008

B. K. Kennedy, S. L. Berger, A. Brunet, J. Campisi, A. M. Cuervo et al., Geroscience: Linking Aging to Chronic Disease, Cell, vol.159, issue.4, pp.709-713, 2014.
DOI : 10.1016/j.cell.2014.10.039
URL : https://doi.org/10.1016/j.cell.2014.10.039

J. Kind and B. Van-steensel, Stochastic genome-nuclear lamina interactions, Nucleus, vol.5, issue.2, pp.124-130, 2014.
DOI : 10.1016/j.molcel.2010.03.016
URL : http://www.tandfonline.com/doi/pdf/10.4161/nucl.28825?needAccess=true

S. W. Knight, N. S. Heiss, T. J. Vulliamy, S. Greschner, G. Stavrides et al., X-Linked Dyskeratosis Congenita Is Predominantly Caused by Missense Mutations in the DKC1 Gene, The American Journal of Human Genetics, vol.65, issue.1, pp.50-58, 1999.
DOI : 10.1086/302446

C. E. Koering, A. Pollice, M. P. Zibella, S. Bauwens, A. Puisieux et al., Human telomeric position effect is determined by chromosomal context and telomeric chromatin integrity, EMBO reports, vol.3, issue.11, pp.1055-1061, 2002.
DOI : 10.1093/embo-reports/kvf215
URL : https://hal.archives-ouvertes.fr/hal-01596225

S. T. Kosak, J. A. Skok, K. L. Medina, R. Riblet, L. Beau et al., Subnuclear Compartmentalization of Immunoglobulin Loci During Lymphocyte Development, Science, vol.296, issue.5565, pp.158-162, 2002.
DOI : 10.1126/science.1068768

N. Kubben, M. Adriaens, W. Meuleman, J. W. Voncken, B. Van-steensel et al., Mapping of lamin A- and progerin-interacting genome regions, Chromosoma, vol.166, issue.6, pp.447-464, 2012.
DOI : 10.1083/jcb.200404107

N. Kubben, W. Zhang, L. Wang, T. C. Voss, J. Yang et al., Repression of the Antioxidant NRF2 Pathway in Premature Aging, Cell, vol.165, issue.6, pp.1361-1374, 2016.
DOI : 10.1016/j.cell.2016.05.017

B. A. Kudlow, M. N. Stanfel, C. R. Burtner, E. D. Johnston, K. et al., Suppression of Proliferative Defects Associated with Processing-defective Lamin A Mutants by hTERT or Inactivation of p53, Molecular Biology of the Cell, vol.19, issue.12, pp.5238-5248, 2008.
DOI : 10.1091/mbc.E08-05-0492

A. Kulkarni, O. Zschenker, G. Reynolds, D. Miller, and J. P. Murnane, Effect of Telomere Proximity on Telomere Position Effect, Chromosome Healing, and Sensitivity to DNA Double-Strand Breaks in a Human Tumor Cell Line, Molecular and Cellular Biology, vol.30, issue.3, pp.578-589, 1128.
DOI : 10.1128/MCB.01137-09

R. I. Kumaran and D. L. Spector, A genetic locus targeted to the nuclear periphery in living cells maintains its transcriptional competence, The Journal of Cell Biology, vol.180, issue.1, pp.51-65, 2008.
DOI : 10.1083/jcb.200404107

C. Lemaitre and W. A. Bickmore, Chromatin at the nuclear periphery and the regulation of genome functions, Histochemistry and Cell Biology, vol.149, issue.2, pp.111-122, 2015.
DOI : 10.1016/j.cell.2012.04.035

E. Lieberman-aiden, N. L. Van-berkum, L. Williams, M. Imakaev, T. Ragoczy et al., Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome, Science, vol.27, issue.2, pp.289-293, 2009.
DOI : 10.1038/nbt.1523

N. Link, P. Kurtz, M. Neal, G. Garcia-hughes, and J. M. Abrams, A p53 enhancer region regulates target genes through chromatin conformations in cis and in trans, Genes & Development, vol.27, issue.22, pp.2433-2438, 2013.
DOI : 10.1101/gad.225565.113

S. Lomvardas, G. Barnea, D. J. Pisapia, M. Mendelsohn, J. Kirkland et al., Interchromosomal Interactions and Olfactory Receptor Choice, Cell, vol.126, issue.2, pp.403-413, 2006.
DOI : 10.1016/j.cell.2006.06.035
URL : https://doi.org/10.1016/j.cell.2006.06.035

C. Lopez-otin, M. A. Blasco, L. Partridge, M. Serrano, and G. Kroemer, The Hallmarks of Aging, Cell, vol.153, issue.6, 2013.
DOI : 10.1016/j.cell.2013.05.039

F. Lottersberger, R. A. Karssemeijer, N. Dimitrova, and T. De-lange, 53BP1 and the LINC Complex Promote Microtubule-Dependent DSB Mobility and DNA Repair, Cell, vol.163, issue.4, pp.880-893, 2015.
DOI : 10.1016/j.cell.2015.09.057
URL : https://doi.org/10.1016/j.cell.2015.09.057

Z. Lou, J. Wei, H. Riethman, J. A. Baur, R. Voglauer et al., Telomere length regulates ISG15 expression in human cells, Aging, vol.1, issue.7, pp.608-621, 2009.
DOI : 10.18632/aging.100066

M. E. Luderus, A. De-graaf, E. Mattia, J. L. Den-blaauwen, M. A. Grande et al., Binding of matrix attachment regions to lamin B1, Cell, vol.70, issue.6, pp.949-959, 1992.
DOI : 10.1016/0092-8674(92)90245-8

M. E. Luderus, J. L. Den-blaauwen, O. J. De-smit, D. A. Compton, and R. Van-driel, Binding of matrix attachment regions to lamin polymers involves single-stranded regions and the minor groove., Molecular and Cellular Biology, vol.14, issue.9, pp.6297-6305, 1994.
DOI : 10.1128/MCB.14.9.6297

R. Lyakhovetsky and Y. Gruenbaum, Studying Lamins in Invertebrate Models, Adv. Exp. Med. Biol, vol.773, pp.245-262, 2014.
DOI : 10.1007/978-1-4899-8032-8_11

A. Maicher, L. Kastner, L. , and B. , Telomeres and disease: Enter TERRA, RNA Biology, vol.584, issue.6, pp.843-849, 2012.
DOI : 10.1016/j.febslet.2010.05.026
URL : http://www.tandfonline.com/doi/pdf/10.4161/rna.20330?needAccess=true

E. Markiewicz, T. Dechat, R. Foisner, R. A. Quinlan, and C. J. Hutchison, Lamin A/C Binding Protein LAP2alpha Is Required for Nuclear Anchorage of Retinoblastoma Protein, Molecular Biology of the Cell, vol.13, issue.12, pp.4401-4413, 2002.
DOI : 10.1091/mbc.E02-07-0450

W. F. Marshall, A. Straight, J. F. Marko, J. Swedlow, A. Dernburg et al., Interphase chromosomes undergo constrained diffusional motion in living cells, Current Biology, vol.7, issue.12, pp.930-939, 1997.
DOI : 10.1016/S0960-9822(06)00412-X
URL : https://doi.org/10.1016/s0960-9822(06)00412-x

P. S. Masny, U. Bengtsson, S. A. Chung, J. H. Martin, B. Van-engelen et al., Localization of 4q35.2 to the nuclear periphery: is FSHD a nuclear envelope disease?, Human Molecular Genetics, vol.13, issue.17, pp.1857-1871, 2004.
DOI : 10.1093/hmg/ddh205

E. Mattioli, M. Columbaro, C. Capanni, N. M. Maraldi, V. Cenni et al., Prelamin A-mediated recruitment of SUN1 to the nuclear envelope directs nuclear positioning in human muscle, Cell Death and Differentiation, vol.53, issue.8, pp.1305-1315, 2011.
DOI : 10.1016/j.yexcr.2007.11.012
URL : https://hal.archives-ouvertes.fr/hal-00614318

E. Mattioli, M. Columbaro, C. Capanni, S. Santi, N. M. Maraldi et al., Drugs affecting prelamin A processing: Effects on heterochromatin organization, Experimental Cell Research, vol.314, issue.3, pp.453-462, 2008.
DOI : 10.1016/j.yexcr.2007.11.012

A. Mattout, M. Goldberg, Y. Tzur, A. Margalit, and Y. Gruenbaum, Specific and conserved sequences in D. melanogaster and C. elegans lamins and histone H2A mediate the attachment of lamins to chromosomes, Journal of Cell Science, vol.120, issue.1, pp.77-85, 2007.
DOI : 10.1242/jcs.03325

R. P. Mccord, A. Nazario-toole, H. Zhang, P. S. Chines, Y. Zhan et al., Correlated alterations in genome organization, histone methylation, and DNA-lamin A/C interactions in Hutchinson-Gilford progeria syndrome, Genome Research, vol.23, issue.2, pp.260-269, 2013.
DOI : 10.1101/gr.138032.112

K. J. Meaburn, E. Cabuy, G. Bonne, N. Levy, G. E. Morris et al., Primary laminopathy fibroblasts display altered genome organization and apoptosis, Aging Cell, vol.44, issue.2, pp.139-153, 2007.
DOI : 10.1242/jcs.01102
URL : http://onlinelibrary.wiley.com/doi/10.1111/j.1474-9726.2007.00270.x/pdf

S. Melcer, H. Hezroni, E. Rand, M. Nissim-rafinia, A. Skoultchi et al., Histone modifications and lamin A regulate chromatin protein dynamics in early embryonic stem cell differentiation, Nature Communications, vol.200, pp.910-920, 1038.
DOI : 10.1111/j.1600-0854.2007.00638.x

W. Meuleman, D. Peric-hupkes, J. Kind, J. B. Beaudry, L. Pagie et al., Constitutive nuclear lamina-genome interactions are highly conserved and associated with A/T-rich sequence, Genome Research, vol.23, issue.2, pp.270-280, 2013.
DOI : 10.1101/gr.141028.112
URL : http://genome.cshlp.org/content/23/2/270.full.pdf

T. Misteli and P. Scaffidi, Genome instability in progeria: when repair gets old, Nature Medicine, vol.13, issue.7, pp.718-719, 2005.
DOI : 10.1093/hmg/ddh265

R. D. Moir, T. P. Spann, H. Herrmann, and R. D. Goldman, Disruption of Nuclear Lamin Organization Blocks the Elongation Phase of DNA Replication, The Journal of Cell Biology, vol.110, issue.6, pp.1179-1192, 2000.
DOI : 10.1007/s004390050686

M. J. Moser, W. L. Bigbee, S. G. Grant, M. J. Emond, R. G. Langlois et al., Genetic instability and hematologic disease risk in Werner syndrome patients and heterozygotes, Cancer Res, vol.60, pp.2492-2496, 2000.

M. J. Moser, A. S. Kamath-loeb, J. E. Jacob, S. E. Bennett, J. Oshima et al., WRN helicase expression in Werner syndrome cell lines, Nucleic Acids Research, vol.28, issue.2, pp.648-654, 2000.
DOI : 10.1093/nar/28.2.648
URL : https://academic.oup.com/nar/article-pdf/28/2/648/9904752/280648.pdf

C. L. Moulson, L. G. Fong, J. M. Gardner, E. A. Farber, G. Go et al., mutations causes severe progeroid syndromes, Human Mutation, vol.281, issue.9, pp.882-889, 2007.
DOI : 10.1002/humu.20536

N. Naetar, B. Korbei, S. Kozlov, M. A. Kerenyi, D. Dorner et al., Loss of nucleoplasmic LAP2?????lamin A complexes causes erythroid and epidermal progenitor hyperproliferation, Nature Cell Biology, vol.7, issue.11, pp.1341-1348, 2006.
DOI : 10.1038/ncb1793

M. Narita, S. Nunez, E. Heard, A. W. Lin, S. A. Hearn et al., Rb-Mediated Heterochromatin Formation and Silencing of E2F Target Genes during Cellular Senescence, Cell, vol.113, issue.6, pp.703-716, 2003.
DOI : 10.1016/S0092-8674(03)00401-X

C. L. Navarro, V. Esteves-vieira, S. Courrier, A. Boyer, T. Duong-nguyen et al., New ZMPSTE24 (FACE1) mutations in patients affected with restrictive dermopathy or related progeroid syndromes and mutation update, European Journal of Human Genetics, vol.30, issue.8, pp.1002-1011, 2014.
DOI : 10.1111/j.1525-1470.2010.01296.x
URL : https://hal.archives-ouvertes.fr/hal-01664301

E. P. Nora, B. R. Lajoie, E. G. Schulz, L. Giorgetti, I. Okamoto et al., Spatial partitioning of the regulatory landscape of the X-inactivation centre Mandibuloacral dysplasia is caused by a mutation in LMNA-encoding lamin A/C, Nature Am. J. Hum. Genet, vol.485, issue.71, pp.381-385, 1086.

A. Ottaviani, E. Gilson, and F. Magdinier, Telomeric position effect: From the yeast paradigm to human pathologies?, Biochimie, vol.90, issue.1, 2008.
DOI : 10.1016/j.biochi.2007.07.022
URL : https://hal.archives-ouvertes.fr/hal-01663623

A. Ottaviani, C. Schluth-bolard, E. Gilson, and F. Magdinier, as a prototype of CTCF and lamins-dependent insulator in human cells, Nucleus, vol.11, issue.1, pp.30-36, 2010.
DOI : 10.1016/j.yexcr.2007.03.028
URL : https://hal.archives-ouvertes.fr/ensl-00817391

A. Ottaviani, C. Schluth-bolard, S. Rival-gervier, A. Boussouar, D. Rondier et al., Identification of a perinuclear positioning element in human subtelomeres that requires A-type lamins and CTCF, The EMBO Journal, vol.264, issue.16, pp.2428-2436, 0201.
DOI : 10.1006/bbrc.2000.3917
URL : https://hal.archives-ouvertes.fr/hal-01663788

J. Padeken and P. Heun, Nucleolus and nuclear periphery: Velcro for heterochromatin, Current Opinion in Cell Biology, vol.28, pp.54-60, 2014.
DOI : 10.1016/j.ceb.2014.03.001

W. Palm and T. De-lange, How Shelterin Protects Mammalian Telomeres, Annual Review of Genetics, vol.42, issue.1, 2008.
DOI : 10.1146/annurev.genet.41.110306.130350

G. Pegoraro, N. Kubben, U. Wickert, H. Gohler, K. Hoffmann et al., Ageing-related chromatin defects through loss of the NURD complex, Meiotic chromosome homology search involves modifications of the nuclear envelope protein Matefin, pp.1261-1267, 1971.
DOI : 10.1093/nar/gkm1056

D. Peric-hupkes and B. Van-steensel, Role of the Nuclear Lamina in Genome Organization and Gene Expression, Cold Spring Harbor Symposia on Quantitative Biology, vol.75, issue.0, pp.517-524, 2010.
DOI : 10.1101/sqb.2010.75.014

J. E. Phillips-cremins, M. E. Sauria, A. Sanyal, T. I. Gerasimova, B. R. Lajoie et al., Architectural Protein Subclasses Shape 3D Organization of Genomes during Lineage Commitment, Cell, vol.153, issue.6, pp.1281-1295, 2013.
DOI : 10.1016/j.cell.2013.04.053
URL : https://doi.org/10.1016/j.cell.2013.04.053

H. Polioudaki, N. Kourmouli, V. Drosou, A. Bakou, P. A. Theodoropoulos et al., Histones H3/H4 form a tight complex with the inner nuclear membrane protein LBR and heterochromatin protein 1, EMBO reports, vol.275, issue.10, pp.920-925, 2001.
DOI : 10.1074/jbc.272.23.14983

J. C. Politz, D. Scalzo, and M. Groudine, The redundancy of the mammalian heterochromatic compartment, Current Opinion in Genetics & Development, vol.37, 2016.
DOI : 10.1016/j.gde.2015.10.007

X. S. Puente, V. Quesada, F. G. Osorio, R. Cabanillas, J. Cadinanos et al., Exome Sequencing and Functional Analysis Identifies BANF1 Mutation as the Cause of a Hereditary Progeroid Syndrome, The American Journal of Human Genetics, vol.88, issue.5, pp.650-656, 2011.
DOI : 10.1016/j.ajhg.2011.04.010

C. Rabl, Über zelltheilung, Morphologisches Jahrbuch, pp.214-330, 1885.

T. Ragoczy, M. A. Bender, A. Telling, R. Byron, and M. Groudine, The locus control region is required for association of the murine beta-globin locus with engaged transcription factories during erythroid maturation, Genes & Development, vol.20, issue.11, pp.1447-1457, 2006.
DOI : 10.1101/gad.1419506

T. S. Rai, A. Puri, T. Mcbryan, J. Hoffman, Y. Tang et al., Human CABIN1 Is a Functional Member of the Human HIRA/UBN1/ASF1a Histone H3.3 Chaperone Complex, Molecular and Cellular Biology, vol.31, issue.19, pp.4107-4118, 1128.
DOI : 10.1128/MCB.05546-11

S. S. Rao, M. H. Huntley, N. C. Durand, E. K. Stamenova, I. D. Bochkov et al., A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping, Cell, vol.159, issue.7, pp.1665-1680, 2014.
DOI : 10.1016/j.cell.2014.11.021

K. L. Reddy, J. M. Zullo, E. Bertolino, and H. Singh, Transcriptional repression mediated by repositioning of genes to the nuclear lamina, Nature, vol.45, issue.7184, pp.243-247, 2008.
DOI : 10.1177/002215549704501201

A. B. Redwood, I. Gonzalez-suarez, G. , and S. , Regulating the levels of key factors in cell cycle and DNA repair: New pathways revealed by lamins, Cell Cycle, vol.10, issue.21, pp.3652-3657, 2011.
DOI : 10.4161/cc.10.21.18201

A. B. Redwood, S. M. Perkins, R. P. Vanderwaal, Z. Feng, K. J. Biehl et al., A dual role for A-type lamins in DNA double-strand break repair, Cell Cycle, vol.1, issue.15, pp.2549-2560, 2011.
DOI : 10.1038/nprot.2006.339

D. Riemer, H. Dodemont, W. , and K. , A nuclear lamin of the nematode Caenorhabditis elegans with unusual structural features; cDNA cloning and gene organization, Eur. J. Cell Biol, vol.62, pp.214-223, 1993.

J. D. Robin, A. T. Ludlow, K. Batten, M. C. Gaillard, G. Stadler et al., transcription is activated by telomere position effect???over long distance upon telomere shortening in muscle cells from patients with facioscapulohumeral dystrophy, Genome Research, vol.25, issue.12, pp.1781-1790115, 2015.
DOI : 10.1101/gr.190660.115
URL : https://hal.archives-ouvertes.fr/hal-01663663

J. D. Robin, A. T. Ludlow, K. Batten, F. Magdinier, G. Stadler et al., Telomere position effect: regulation of gene expression with progressive telomere shortening over long distances, Genes & Development, vol.28, issue.22, pp.2464-2476, 2014.
DOI : 10.1101/gad.251041.114
URL : https://hal.archives-ouvertes.fr/hal-01663660

M. Sadaie, R. Salama, T. Carroll, K. Tomimatsu, T. Chandra et al., Redistribution of the Lamin B1 genomic binding profile affects rearrangement of heterochromatic domains and SAHF formation during senescence, Genes & Development, vol.27, issue.16, pp.1800-1808, 2013.
DOI : 10.1101/gad.217281.113

N. Saksouk, E. Simboeck, and J. And-dejardin, Constitutive heterochromatin formation and transcription in mammals, Epigenetics & Chromatin, vol.8, issue.1, pp.1756-8935, 2015.
DOI : 10.1007/s10577-011-9208-5
URL : https://hal.archives-ouvertes.fr/hal-01144005

B. Sarg, E. Koutzamani, W. Helliger, I. Rundquist, and H. H. Lindner, Postsynthetic Trimethylation of Histone H4 at Lysine 20 in Mammalian Tissues Is Associated with Aging, Journal of Biological Chemistry, vol.264, issue.42, pp.39195-39201, 2002.
DOI : 10.1016/0014-4827(87)90293-X

S. A. Savage, Human Telomeres and Telomere Biology Disorders, Prog. Mol. Biol. Trans. Sci, vol.125, pp.41-66, 2014.
DOI : 10.1016/B978-0-12-397898-1.00002-5

P. Scaffidi and T. Misteli, Lamin A-Dependent Nuclear Defects in Human Aging, Science, vol.312, issue.5776, 2006.
DOI : 10.1126/science.1127168
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855250/pdf

E. C. Schirmer and R. Foisner, Proteins that associate with lamins: Many faces, many functions, Experimental Cell Research, vol.313, issue.10, 2007.
DOI : 10.1016/j.yexcr.2007.03.012

J. B. Serrano, E. S. Da-cruz, R. , and S. , Lamina Associated Polypeptide 1 (LAP1) Interactome and Its Functional Features, Membranes, vol.43, issue.1, p.10, 2016.
DOI : 10.1093/nar/gkq537
URL : http://www.mdpi.com/2077-0375/6/1/8/pdf

T. Sexton, E. Yaffe, E. Kenigsberg, F. Bantignies, B. Leblanc et al., Three-Dimensional Folding and Functional Organization Principles of the Drosophila Genome, Cell, vol.148, issue.3, pp.458-472, 2012.
DOI : 10.1016/j.cell.2012.01.010

P. P. Shah, G. Donahue, G. L. Otte, B. C. Capell, D. M. Nelson et al., Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape, Genes & Development, vol.27, issue.16, pp.1787-1799, 2013.
DOI : 10.1101/gad.223834.113

L. Shao, C. A. Shaw, X. Y. Lu, T. Sahoo, C. A. Bacino et al., Identification of chromosome abnormalities in subtelomeric regions by microarray analysis: A study of 5,380 cases, American Journal of Medical Genetics Part A, vol.68, issue.17, pp.2242-2251, 2008.
DOI : 10.1016/0168-9525(91)90103-W

T. Shimi, V. Butin-israeli, S. A. Adam, R. B. Hamanaka, A. E. Goldman et al., The role of nuclear lamin B1 in cell proliferation and senescence, Genes & Development, vol.25, issue.24, pp.2579-2593, 2011.
DOI : 10.1101/gad.179515.111

T. Shimi, K. Pfleghaar, S. Kojima, C. G. Pack, I. Solovei et al., The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription, Genes & Development, vol.22, issue.24, pp.3409-3421, 2008.
DOI : 10.1101/gad.1735208

R. L. Shoeman and P. Traub, The in vitro DNA-binding properties of purified nuclear lamin proteins and vimentin, J. Biol. Chem, vol.265, pp.9055-9061, 1990.

D. K. Shumaker, T. Dechat, A. Kohlmaier, S. A. Adam, M. R. Bozovsky et al., Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging, Proceedings of the National Academy of Sciences, vol.45, issue.12, pp.8703-8708, 2006.
DOI : 10.1177/002215549704501201

I. Solovei, A. S. Wang, K. Thanisch, C. S. Schmidt, S. Krebs et al., LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation, Cell, vol.152, issue.3, pp.584-598, 2013.
DOI : 10.1016/j.cell.2013.01.009
URL : https://doi.org/10.1016/j.cell.2013.01.009

R. Somech, S. Shaklai, N. Amariglio, G. Rechavi, and A. J. Simon, Nuclear Envelopathies???Raising the Nuclear Veil, Pediatric Research, vol.36, issue.5 Part 2, pp.8-15, 2005.
DOI : 10.1038/ng1453

R. Somech, S. Shaklai, O. Geller, N. Amariglio, A. J. Simon et al., The nuclear-envelope protein and transcriptional repressor LAP2?? interacts with HDAC3 at the nuclear periphery, and induces histone H4 deacetylation, Journal of Cell Science, vol.118, issue.17, pp.4017-4025, 2005.
DOI : 10.1242/jcs.02521

D. L. Spector, SnapShot: Cellular Bodies, Cell, vol.127, issue.5, 2006.
DOI : 10.1016/j.cell.2006.11.026
URL : https://doi.org/10.1016/j.cell.2006.11.026

V. Srsen, N. Korfali, and E. C. Schirmer, Nuclear envelope influences on cell-cycle progression, Biochemical Society Transactions, vol.115, issue.6, pp.1742-1746, 2011.
DOI : 10.1073/pnas.0730821100
URL : http://www.biochemsoctrans.org/content/ppbiost/39/6/1742.full.pdf

E. C. Swanson, B. Manning, H. Zhang, L. , and J. B. , Higher-order unfolding of satellite heterochromatin is a consistent and early event in cell senescence, The Journal of Cell Biology, vol.117, issue.6, pp.929-942, 2013.
DOI : 10.1083/jcb.201306073.dv

P. Taimen, K. Pfleghaar, T. Shimi, D. Moller, K. Ben-harush et al., A progeria mutation reveals functions for lamin A in nuclear assembly, architecture, and chromosome organization, Proceedings of the National Academy of Sciences, vol.155, issue.2, pp.20788-20793, 2009.
DOI : 10.1016/j.jsb.2006.03.026

R. Tam, K. P. Smith, L. , and J. B. , The 4q subtelomere harboring the FSHD locus is specifically anchored with peripheral heterochromatin unlike most human telomeres, The Journal of Cell Biology, vol.114, issue.2, pp.269-279, 2004.
DOI : 10.1016/S1097-2765(04)00029-2

H. Tanabe, S. Muller, M. Neusser, J. Von-hase, E. Calcagno et al., Evolutionary conservation of chromosome territory arrangements in cell nuclei from higher primates, Proceedings of the National Academy of Sciences, vol.276, issue.1-2, pp.4424-4429, 2002.
DOI : 10.1016/S0378-1119(01)00644-8

Z. Tang, O. J. Luo, X. Li, M. Zheng, J. J. Zhu et al., CTCF-Mediated Human 3D Genome Architecture Reveals Chromatin Topology for Transcription, Cell, vol.163, issue.7, pp.1611-1627, 2015.
DOI : 10.1016/j.cell.2015.11.024
URL : https://hal.archives-ouvertes.fr/hal-01336466

H. Taniura, C. Glass, and L. Gerace, A chromatin binding site in the tail domain of nuclear lamins that interacts with core histones, The Journal of Cell Biology, vol.131, issue.1, pp.33-44, 1995.
DOI : 10.1083/jcb.131.1.33

S. Van-koningsbruggen, M. Gierlinski, P. Schofield, D. Martin, G. J. Barton et al., High-Resolution Whole-Genome Sequencing Reveals That Specific Chromatin Domains from Most Human Chromosomes Associate with Nucleoli, Molecular Biology of the Cell, vol.21, issue.21, pp.3735-3748, 2010.
DOI : 10.1091/mbc.E10-06-0508

B. Van-steensel and S. Henikoff, Identification of in vivo DNA targets of chromatin proteins using tethered Dam methyltransferase, Nature Biotechnology, vol.108, issue.4, pp.424-428, 2000.
DOI : 10.1073/pnas.97.2.716

S. Vidak, N. Kubben, T. Dechat, and R. Foisner, Proliferation of progeria cells is enhanced by lamina-associated polypeptide 2?? (LAP2??) through expression of extracellular matrix proteins, Genes & Development, vol.29, issue.19, pp.2022-2036, 2015.
DOI : 10.1101/gad.263939.115

C. Weierich, A. Brero, S. Stein, J. Von-hase, C. Cremer et al., Three-dimensional arrangements of centromeres and telomeres in nuclei of human and murine lymphocytes, Chromosome Research, vol.11, issue.5, pp.485-502, 2003.
DOI : 10.1023/A:1025016828544

R. R. Williams, V. Azuara, P. Perry, S. Sauer, M. Dvorkina et al., Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus, Journal of Cell Science, vol.119, issue.1, pp.132-140, 2006.
DOI : 10.1242/jcs.02727

A. M. Wood, J. M. Rendtlew-danielsen, C. A. Lucas, E. L. Rice, D. Scalzo et al., TRF2 and lamin A/C interact to facilitate the functional organization of chromosome ends, Nature Communications, vol.463, 2014.
DOI : 10.1158/0008-5472.CAN-04-1992

Q. Ye and H. J. Worman, HP1, Journal of Biological Chemistry, vol.269, issue.25, pp.14653-14656, 1996.
DOI : 10.1126/science.7660126

X. Ye, B. Zerlanko, A. Kennedy, G. Banumathy, R. Zhang et al., Downregulation of Wnt Signaling Is a Trigger for Formation of Facultative Heterochromatin and Onset of Cell Senescence in Primary Human Cells, Molecular Cell, vol.27, issue.2, pp.183-196, 2007.
DOI : 10.1016/j.molcel.2007.05.034

R. Zhang, A. , and P. D. , Heterochromatin and its Relationship to Cell Senescence and Cancer Therapy, Cell Cycle, vol.6, issue.7, 2007.
DOI : 10.4161/cc.6.7.4079
URL : http://www.tandfonline.com/doi/pdf/10.4161/cc.6.7.4079?needAccess=true

R. Zhang, W. Chen, A. , and P. D. , Molecular Dissection of Formation of Senescence-Associated Heterochromatin Foci, Molecular and Cellular Biology, vol.27, issue.6, pp.2343-2358, 2007.
DOI : 10.1128/MCB.02019-06

R. Zhang, M. V. Poustovoitov, X. Ye, H. A. Santos, W. Chen et al., Formation of MacroH2A-Containing Senescence-Associated Heterochromatin Foci and Senescence Driven by ASF1a and HIRA, Developmental Cell, vol.8, issue.1, pp.19-30, 2005.
DOI : 10.1016/j.devcel.2004.10.019
URL : https://doi.org/10.1016/j.devcel.2004.10.019

S. Zhang, D. E. Schones, C. Malicet, M. Rochman, M. Zhou et al., High Mobility Group Protein N5 (HMGN5) and Lamina-associated Polypeptide 2?? (LAP2??) Interact and Reciprocally Affect Their Genome-wide Chromatin Organization, Journal of Biological Chemistry, vol.9, issue.25, pp.18104-18109, 2013.
DOI : 10.1016/j.cell.2007.05.009
URL : http://www.jbc.org/content/288/25/18104.full.pdf

K. Zhao, A. Harel, N. Stuurman, D. Guedalia, and Y. Gruenbaum, Binding of matrix attachment regions to nuclear lamin is mediated by the rod domain and depends on the lamin polymerization state, FEBS Letters, vol.131, issue.1-2, pp.161-164, 1996.
DOI : 10.1083/jcb.131.1.33

D. Zink, M. D. Amaral, A. Englmann, S. Lang, L. A. Clarke et al., Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei, The Journal of Cell Biology, vol.113, issue.6, pp.815-825, 2004.
DOI : 10.1016/S1046-2023(02)00289-X

J. M. Zullo, I. A. Demarco, R. Pique-regi, D. J. Gaffney, C. B. Epstein et al., DNA Sequence-Dependent Compartmentalization and Silencing of Chromatin at the Nuclear Lamina, Cell, vol.149, issue.7, pp.1474-1487, 2012.
DOI : 10.1016/j.cell.2012.04.035