3D nuclear topology dynamics of the 4q35 subtelomeric region linked to Facio-Scapulo-Humeral Dystrophy in skeletal muscle cells and hiPSC

Camille Dion (1) , Marie-Cécile Gaillard (1) , Arnaud Lagarde (1) , Cherif Badja (1) , Armand Tasmadjian (1) , Claire El-Yazidi (1) , Sylviane Olschwang (1, 2, 3) , Karine Nguyen (1, 4) , Frédérique Magdinier (1) , Stéphane Roche (1)

1 GMGF - Génétique Médicale et Génomique Fonctionnelle
2 Hôpital Européen [Fondation Ambroise Paré - Marseille]
3 Département d'Oncologie [Hôpital Clairval - Marseille]
4 Département de génétique médicale [Hôpital de la Timone - APHM]

Keywords: Human induced pluripotent stem cell; FSHD; Nulcear topology; 3D organization; D4Z4; Epigenetics

Domains: Life Sciences [q-bio]; Neurons and Cognition [q-bio.NC]; Neurobiology; Life Sciences [q-bio]; Genetics; Human genetics; Life Sciences [q-bio]; Biotechnology; Life Sciences [q-bio]; Cellular Biology; Subcellular Processes [q-bio.SC]; Life Sciences [q-bio]; Biochemistry, Molecular Biology; Genomics [q-bio.GN]; Life Sciences [q-bio]; Biochemistry, Molecular Biology; Molecular biology

Camille Dion, Marie-Cécile Gaillard, Arnaud Lagarde, Cherif Badja, Armand Tasmadjian, et al.. 3D nuclear topology dynamics of the 4q35 subtelomeric region linked to Facio-Scapulo-Humeral Dystrophy in skeletal muscle cells and hiPSC. EMBO Conference - Chromatin and Epigenetics, May 2015, Heidelberg, Germany. ⟨hal-01675614⟩