Synthesis and biological evaluation of novel anticancer bivalent colchicine–tubulizine hybrids

Yulia Malysheva , Sébastien Combes (1) , Diane Allegro (2) , Vincent Peyrot (2) , Paul Knochel , Andrei Gavryushin , Alexey Yu. Fedorov

1 ICR - Institut de Chimie Radicalaire
2 CRO2 - Centre de Recherches en Oncologie biologique et Oncopharmacologie

Domaines: Sciences du Vivant [q-bio]; Biochimie, Biologie Moléculaire; Biologie cellulaire; Cancer; Sciences pharmaceutiques

Yulia Malysheva, Sébastien Combes, Diane Allegro, Vincent Peyrot, Paul Knochel, et al.. Synthesis and biological evaluation of novel anticancer bivalent colchicine–tubulizine hybrids. Bioorganic and Medicinal Chemistry, 2012, 20 (14), pp.4271 - 4278. ⟨10.1016/j.bmc.2012.05.072⟩. ⟨hal-01749009⟩