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S. H. Thibault-carpentier, M. D. , T. L. , B. M. , G. et al., with assistance from Emeline Pollet (CIML) This work was supported by Wellcome Trust UK Project Grant 094763 to C the Medical Research Council UK and grants from the Netherlands Organization for Scientific Research (NWO, VIDI 917-76- 365) to B.E.C. C.L.S. is supported by a Horizon 2020 Marie Curie Intra-European Fellowship (IEF). B.E.C. is currently supported by the German Research Foundation (DFG) and the Research Centre for Immunotherapy (FZI) Mainz. Author contributions Performed experiments and data analysis