Abstract : Background: SacPox, an enzyme from the extremophilic crenarchaeal Sulfolobus acidocaldarius (Sac), was isolated by virtue of its phosphotriesterase (or paraoxonase; Pox) activity, i.e. its ability to hydrolyze the neurotoxic organophosphorus insecticides. Later on, SacPox was shown to belong to the Phosphotriesterase-Like Lactonase family that comprises natural lactonases, possibly involved in quorum sensing, and endowed with promiscuous, phosphotriesterase activity.
https://hal-amu.archives-ouvertes.fr/hal-01771510 Contributor : Administrateur HAL AMUConnect in order to contact the contributor Submitted on : Thursday, April 19, 2018 - 3:34:40 PM Last modification on : Tuesday, October 19, 2021 - 10:59:49 PM Long-term archiving on: : Tuesday, September 18, 2018 - 4:29:22 PM
Janek Bzdrenga, Julien Hiblot, Guillaume Gotthard, Charlotte Champion, Mikael Elias, et al.. SacPox from the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius is a proficient lactonase. BMC Research Notes, BioMed Central, 2014, 7 (1), ⟨10.1186/1756-0500-7-333⟩. ⟨hal-01771510⟩