O. Moranne, M. Froissart, J. Rossert, C. Gauci, J. Boffa et al., Timing of Onset of CKD-Related Metabolic Complications, Journal of the American Society of Nephrology, vol.20, issue.1, pp.164-71, 2009.
DOI : 10.1681/ASN.2008020159
URL : https://hal.archives-ouvertes.fr/inserm-00555033

K. Disease, Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease, Kidney Int Suppl, vol.3, pp.1-150, 2013.

I. Macdougall, Role of uremic toxins in exacerbating anemia in renal failure, Kidney Int Feb, vol.78, pp.67-72, 2001.

J. Babitt, Mechanisms of Anemia in CKD, Journal of the American Society of Nephrology, vol.23, issue.10, pp.1631-1635, 2012.
DOI : 10.1681/ASN.2011111078

M. Pfeffer, E. Burdmann, C. Chen, M. Cooper, D. De-zeeuw et al., A Trial of Darbepoetin Alfa in Type 2 Diabetes and Chronic Kidney Disease, New England Journal of Medicine, vol.361, issue.21, pp.2019-2051, 2009.
DOI : 10.1056/NEJMoa0907845

D. Kushner, B. Beckman, L. Nguyen, S. Chen, D. Santina et al., Polyamines in the anemia of end-stage renal disease, Kidney International, vol.39, issue.4, pp.725-757, 1991.
DOI : 10.1038/ki.1991.88

C. Chiang, T. Tanaka, R. Inagi, T. Fujita, and M. Nangaku, Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in a HIF-dependent manner, Laboratory Investigation, vol.72, issue.11, pp.1564-71, 2011.
DOI : 10.1182/blood-2007-10-115857

B. Gondouin, C. Cerini, L. Dou, M. Sallée, A. Duval-sabatier et al., Indolic uremic solutes increase tissue factor production in endothelial cells by the aryl hydrocarbon receptor pathway, Kidney International, vol.84, issue.4, pp.733-777, 2013.
DOI : 10.1038/ki.2013.133
URL : https://hal.archives-ouvertes.fr/hal-01610430

H. Asai, J. Hirata, A. Hirano, K. Hirai, S. Seki et al., Activation of aryl hydrocarbon receptor mediates suppression of hypoxia-inducible factor-dependent erythropoietin expression by indoxyl sulfate, American Journal of Physiology-Cell Physiology, vol.110, issue.2, pp.142-50, 2016.
DOI : 10.1038/sj.ki.5000340

M. Ahmed, M. Abed, J. Voelkl, and F. Lang, Triggering of suicidal erythrocyte death by uremic toxin indoxyl sulfate, BMC Nephrology, vol.16, issue.2, pp.14-244
DOI : 10.1053/j.ackd.2008.12.008

I. Wu, K. Hsu, C. Sun, C. Tsai, M. Wu et al., Oral adsorbent AST-120 potentiates the effect of erythropoietin-stimulating agents on Stage 5 chronic kidney disease patients: a randomized crossover study, Nephrology Dialysis Transplantation, vol.4, issue.10, pp.1719-1746, 2014.
DOI : 10.2215/CJN.03980609

J. Gunnell, J. Yeun, T. Depner, and G. Kaysen, Acute-phase response predicts erythropoietin resistance in hemodialysis and peritoneal dialysis patients, American Journal of Kidney Diseases, vol.33, issue.1
DOI : 10.1016/S0272-6386(99)70259-3

J. Daugirdas, Second generation logarithmic estimates of single-pool variable volume Kt/V: an analysis of error, J Am Soc Nephrol, vol.4, pp.1205-1218, 1993.

D. Regidor, J. Kopple, C. Kovesdy, R. Kilpatrick, C. Mcallister et al., Associations between Changes in Hemoglobin and Administered Erythropoiesis-Stimulating Agent and Survival in Hemodialysis Patients, Journal of the American Society of Nephrology, vol.17, issue.4, pp.1181-91, 2006.
DOI : 10.1681/ASN.2005090997

J. López-gómez, J. Portolés, and P. Aljama, Factors that condition the response to erythropoietin in patients on hemodialysis and their relation to mortality, Kidney International, vol.74, pp.75-81, 2008.
DOI : 10.1038/ki.2008.523

S. Fukuma, T. Yamaguchi, S. Hashimoto, S. Nakai, K. Iseki et al., Erythropoiesis-Stimulating Agent Responsiveness and Mortality in Hemodialysis Patients: Results from a Cohort Study From the Dialysis Registry in Japan, American Journal of Kidney Diseases, vol.59, issue.1, pp.108-124
DOI : 10.1053/j.ajkd.2011.07.014

R. Calaf, C. Cerini, C. Genovesio, P. Verhaeghe, N. Jourde-chiche et al., Determination of uremic solutes in biological fluids of chronic kidney disease patients by HPLC assay, Journal of Chromatography B, vol.879, issue.23, pp.2281-2287, 2011.
DOI : 10.1016/j.jchromb.2011.06.014
URL : https://hal.archives-ouvertes.fr/hal-01460285

S. Wallner, J. Kurnick, H. Ward, R. Vautrin, and A. Alfrey, The anemia of chronic renal failure and chronic diseases: in vitro studies of erythropoiesis, Blood, vol.47, issue.4, pp.561-570, 1976.

S. Wallner and R. Vautrin, The anemia of chronic renal failure: studies of the effect of organic solvent extraction of serum, J Lab Clin Med, vol.92, issue.3, pp.363-372, 1978.

T. Tanaka, J. Yamaguchi, Y. Higashijima, and M. Nangaku, Indoxyl sulfate signals for rapid mRNA stabilization of Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) and suppresses the expression of hypoxia-inducible genes in experimental CKD and uremia, The FASEB Journal, vol.18, issue.10, p.2013
DOI : 10.1007/s00424-009-0748-x

L. Dou and S. Burtey, The harmful effect of indoxyl sulfate on neovascularization in chronic kidney disease, Kidney International, vol.89, issue.3, pp.532-536, 2016.
DOI : 10.1016/j.kint.2015.12.030
URL : https://hal.archives-ouvertes.fr/hal-01464929

J. Huang, C. Hsu, C. Yang, C. Hung, and W. Huang, Role of anuria in the relationship between indoxyl sulfate and anemia in peritoneal dialysis patients. Ther Clin Risk Manag, pp.1797-803, 2016.

M. Sallée, L. Dou, C. Cerini, S. Poitevin, P. Brunet et al., The Aryl Hydrocarbon Receptor-Activating Effect of Uremic Toxins from Tryptophan Metabolism: A New Concept to Understand Cardiovascular Complications of Chronic Kidney Disease, Toxins, vol.105, issue.3, pp.934-983, 2014.
DOI : 10.1021/bi801913w

P. Aronov, F. Luo, N. Plummer, Z. Quan, S. Holmes et al., Colonic Contribution to Uremic Solutes, Journal of the American Society of Nephrology, vol.22, issue.9, pp.1769-76, 2011.
DOI : 10.1681/ASN.2010121220

S. Marzocco, D. Piaz, F. , D. Micco, L. Torraca et al., Very Low Protein Diet Reduces Indoxyl Sulfate Levels in Chronic Kidney Disease, Blood Purification, vol.35, issue.1-3, pp.1-3196, 2013.
DOI : 10.1159/000346628

T. Niwa, T. Yazawa, M. Ise, M. Sugano, T. Kodama et al., Inhibitory Effect of Oral Sorbent on Accumulation of Albumin-Bound Indoxyl Sulfate in Serum of Experimental Uremic Rats, Nephron, vol.57, issue.1, pp.84-92, 1991.
DOI : 10.1159/000186222