R. W. Connors and A. J. Bridges, A specific inhibitor of the epidermal growth factor receptor tyrosine kinase, Science, vol.265, pp.1093-1095, 1994.

N. Galeotti and P. Gratteri, Structural Investigation of the 7-Chloro-3-hydroxy-1H- quinazoline-2,4-dione. Scaffold to Obtain AMPA and Kainate Receptor Selective Antagonists. Synthesis, Pharmacological, and Molecular Modeling Studies, J. Med. Chem, vol.49, pp.6015-6026, 2006.

N. Malecki, P. Carato, G. Rigo, J. F. Goossens, R. Houssin et al., Synthesis of condensed quinolines and quinazolines as DNA ligands, Bioorganic & Medicinal Chemistry, vol.12, issue.3, pp.641-647, 2004.
DOI : 10.1016/j.bmc.2003.10.014

L. A. Doyle and D. D. Ross, Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2), Oncogene, vol.22, issue.47, pp.7340-7358, 2003.
DOI : 10.1038/nm0901-1028

E. A. Henderson, V. Bavetsias, D. S. Theti, S. C. Wilson, R. Clauss et al., Targeting the ??-folate receptor with cyclopenta[g]quinazoline-based inhibitors of thymidylate synthase, Bioorganic & Medicinal Chemistry, vol.14, issue.14, pp.5020-5042, 2006.
DOI : 10.1016/j.bmc.2006.03.001

A. Foster, H. A. Coffrey, M. J. Morin, and F. Rastinejad, Pharmacological Rescue of Mutant p53 Conformation and Function, Science, vol.286, issue.5449, pp.2507-2510, 1999.
DOI : 10.1126/science.286.5449.2507

T. Chien, C. Chen, F. Yu, J. Chern, and X. Nucleosides, Nucleosides XI. Synthesis and Antiviral Evaluation of 5???-Alkylthio-5???-deoxy Quinazolinone Nucleoside Derivatives as S-Adenosyl-L-homocysteine Analogs, CHEMICAL & PHARMACEUTICAL BULLETIN, vol.52, issue.12, pp.1422-1426, 2004.
DOI : 10.1248/cpb.52.1422

T. Herget, M. Freitag, M. Morbitzer, R. Kupfer, T. Stamminger et al., Novel Chemical Class of pUL97 Protein Kinase-Specific Inhibitors with Strong Anticytomegaloviral Activity, Antimicrobial Agents and Chemotherapy, vol.48, issue.11, pp.4154-4162, 2004.
DOI : 10.1128/AAC.48.11.4154-4162.2004

T. A. Martin, A. G. Wheeler, R. F. Majewski, J. R. Corrigan, and . Sulfanilamidoquinazolines, Sulfanilamidoquinazolines, Journal of Medicinal Chemistry, vol.7, issue.6, pp.812-814, 1964.
DOI : 10.1021/jm00336a033

J. Kunes, J. Bazant, M. Pour, K. Waisser, M. Slosarek et al., Quinazoline derivatives with antitubercular activity, Il Farmaco, vol.55, issue.11-12, pp.725-729, 2000.
DOI : 10.1016/S0014-827X(00)00100-2

K. Waisser, J. Gregor, H. Dostal, J. Kunes, L. Kubicova et al., Influence of the replacement of the oxo function with the thioxo group on the antimycobacterial activity of 3-aryl-6,8-dichloro-2H-1,3-benzoxazine-2,4(3H)-diones and 3-arylquinazoline-2,4(1H,3H)-diones, benzoxazine-2,4(3H)-diones and 3-arylquinazoline- 2,4(1H,3H)-diones, pp.803-807, 2001.
DOI : 10.1016/S0014-827X(01)01134-X

R. Gundla, R. Kazemi, R. Sanam, R. Muttineni, J. A. Sarma et al., Discovery of Novel Small-Molecule Inhibitors of Human Epidermal Growth Factor Receptor-2: Combined Ligand and Target-Based Approach, Journal of Medicinal Chemistry, vol.51, issue.12, pp.3367-3377, 2008.
DOI : 10.1021/jm7013875

G. W. Rewcastle, B. D. Palmer, A. J. Bridges, H. D. Showalter, L. Sun et al., Tyrosine Kinase Inhibitors. 9. Synthesis and Evaluation of Fused Tricyclic Quinazoline Analogues as ATP Site Inhibitors of the Tyrosine Kinase Activity of the Epidermal Growth Factor Receptor, Journal of Medicinal Chemistry, vol.39, issue.4, pp.918-928, 1996.
DOI : 10.1021/jm950692f

A. Luth and W. Lowe, Syntheses of 4-(indole-3-yl)quinazolines ??? A new class of epidermal growth factor receptor tyrosine kinase inhibitors, European Journal of Medicinal Chemistry, vol.43, issue.7, pp.1478-1488, 2008.
DOI : 10.1016/j.ejmech.2007.09.018

J. F. Mendes-da-silva, M. Walters, S. Damluji, and C. R. Ganellin, Molecular features of the prazosin molecule required for activation of Transport-P, Bioorganic & Medicinal Chemistry, vol.16, issue.15, pp.7254-7263, 2008.
DOI : 10.1016/j.bmc.2008.06.037

P. Vanelle, M. P. De-meo, J. Maldonado, R. Nouguier, M. P. Crozet et al., ??tude g??notoxique de d??riv??s de l'oxazolidine: influence du groupe nitro, European Journal of Medicinal Chemistry, vol.25, issue.3, pp.241-250, 1990.
DOI : 10.1016/0223-5234(90)90207-J

M. P. Crozet, L. Giraud, J. F. Sabuco, P. Vanelle, and M. S. Barreau, SRN1 reactions of a tetrasubstituted-1,4-benzoquinone, Tetrahedron Letters, vol.32, issue.33, pp.4125-4128, 1991.
DOI : 10.1016/S0040-4039(00)79881-9

P. G. Baraldi, H. El-kashef, A. R. Farghaly, P. Vanelle, and F. Fruttarolo, Synthesis of new pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines and related heterocycles, Tetrahedron, vol.60, issue.23, pp.5093-5104, 2004.
DOI : 10.1016/j.tet.2004.04.010

N. Boufatah, A. Gellis, J. Maldonado, and P. Vanelle, Efficient microwave-assisted synthesis of new sulfonylbenzimidazole-4,7-diones: heterocyclic quinones with potential antitumor activity, Tetrahedron, vol.60, issue.41, pp.9131-9137, 2004.
DOI : 10.1016/j.tet.2004.07.070

J. Reboul, S. Rault, and P. Rathelot, Synthesis and in vitro antiplasmodial evaluation of 4-anilino-2-trichloromethylquinazolines, Bioorg. Med. Chem, vol.17, pp.4313-4322, 2009.

Y. Kabri, N. Azas, A. Dumètre, S. Hutter, M. Laget et al., Original quinazoline derivatives displaying antiplasmodial properties, European Journal of Medicinal Chemistry, vol.45, issue.2, pp.616-622, 2010.
DOI : 10.1016/j.ejmech.2009.11.005

URL : https://hal.archives-ouvertes.fr/hal-01460232

C. Castera-ducros, N. Azas, P. Verhaeghe, S. Hutter, P. Garrigue et al., Targeting the human malaria parasite Plasmodium falciparum: In vitro identification of a new antiplasmodial hit in 4-phenoxy-2-trichloromethylquinazoline series, European Journal of Medicinal Chemistry, vol.46, issue.9, pp.4184-4191, 2011.
DOI : 10.1016/j.ejmech.2011.06.021

URL : https://hal.archives-ouvertes.fr/hal-01061831

P. Verhaeghe, A. Dumètre, C. Castera-ducros, S. Hutter, M. Laget et al., 4-Thiophenoxy-2-trichloromethyquinazolines display in vitro selective antiplasmodial activity against the human malaria parasite Plasmodium falciparum, Bioorganic & Medicinal Chemistry Letters, vol.21, issue.19, pp.6003-6006, 2011.
DOI : 10.1016/j.bmcl.2011.06.113

URL : https://hal.archives-ouvertes.fr/hal-01061830

K. Augart and G. Kresze, Schönberger, N. 1,6-Cyclisierungen von Phenylimino methyliminokumulenen: Bildung von Chinazolinderivaten, Justus Liebigs Ann. Chem, pp.1457-1466, 1973.

W. Ried, B. Heine, W. Merkel, and N. Kothe, Neuartige Synthese von 4-Tosylimino-3,4-dihydrochinazolin-Derivaten, Synthesis, vol.1976, issue.08, pp.534-535, 1976.
DOI : 10.1055/s-1976-24112

G. Nordvall and U. Yngve, Novel Quinazolines as 5-HT6 Modulators II, 2007.

K. Yokoyama, N. Ishikawa, S. Igarashi, N. Kawano, N. Masuda et al., Potent and orally bioavailable CCR4 antagonists: Synthesis and structure???activity relationship study of 2-aminoquinazolines, Bioorganic & Medicinal Chemistry, vol.17, issue.1, pp.64-73, 2009.
DOI : 10.1016/j.bmc.2008.11.020

P. Verhaeghe, P. Rathelot, A. Gellis, S. Rault, and P. Vanelle, Highly efficient microwave assisted ??-trichlorination reaction of ??-methylated nitrogen containing heterocycles, Tetrahedron, vol.62, issue.34, pp.8173-8176, 2006.
DOI : 10.1016/j.tet.2006.05.081

URL : https://hal.archives-ouvertes.fr/hal-00096229