Inside the Chamber of Secrets of the Type III Secretion System

E. Cascales (1)

1 LISM - Laboratoire d'ingénierie des systèmes macromoléculaires

The bacterial Type III secretion system is a specialized machine that injects effectors into eukaryotic cells to manipulate the host cell physiology. In this issue of Cell, Hu et al. use electron cryo-tomography to reveal an unprecedented level of details regarding the architecture of this machine and the conformational changes that occur during its assembly.

Domaines: Sciences du Vivant [q-bio]

E. Cascales. Inside the Chamber of Secrets of the Type III Secretion System. Cell, 2017, 168 (6), pp.949 - 951. ⟨10.1016/j.cell.2017.02.028⟩. ⟨hal-01780709⟩