Stacking the DEK: From chromatin topology to cancer stem cells, Cell Cycle, vol.12, issue.1, p.23255114, 2013. ,
Structure-specific binding of the proto-oncogene protein DEK to DNA, Nucleic Acids Res, vol.31, issue.23, p.290247, 2003. ,
The ubiquitous chromatin protein DEK alters the structure of DNA by introducing positive supercoils, J Biol Chem, vol.277, issue.28, p.11997399, 2002. ,
The DEK protein-an abundant and ubiquitous constituent of mammalian chromatin, Gene, vol.343, issue.1, p.15563827, 2004. ,
The distribution of the DEK protein in mammalian chromatin. Biochemical and biophysical research communications, vol.358, p.17524367, 2007. ,
IRAK1 is a novel DEK transcriptional target and is essential for head and neck cancer cell survival, Oncotarget, vol.6, issue.41, p.26527316, 2015. ,
The DEK oncogene activates VEGF expression and promotes tumor angiogenesis and growth in HIF-1alpha-dependent and-independent manners, Oncotarget, vol.7, issue.17, p.5029660, 2016. ,
DOI : 10.18632/oncotarget.8060
URL : http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=8060&path%5B%5D=24193
Negative regulation of the RelA/p65 transactivation function by the product of the DEK proto-oncogene, J Biol Chem, vol.281, issue.37, p.16829531, 2006. ,
Transcriptional regulation of 1-cys peroxiredoxin by the proto-oncogene protein DEK, Molecular medicine reports, vol.3, issue.5, p.21472329, 2010. ,
Proteomic analysis of apoptosis related proteins regulated by proto-oncogene protein DEK, Journal of cellular biochemistry, vol.106, issue.6, 2009. ,
DOI : 10.1002/jcb.22083
The human DEK oncogene regulates DNA damage response signaling and repair, Nucleic Acids Res, vol.39, 2011. ,
DOI : 10.1093/nar/gkr454
URL : https://academic.oup.com/nar/article-pdf/39/17/7465/16777557/gkr454.pdf
Chromatin redistribution of the DEK oncoprotein represses hTERT transcription in leukemias, Neoplasia, vol.16, issue.1, p.3927101, 2014. ,
SET and PARP1 remove DEK from chromatin to permit access by the transcription machinery, Nature structural & molecular biology, vol.14, issue.6, pp.548-55, 2007. ,
DOI : 10.1038/nsmb1248
DEK protein overexpression predicts poor prognosis in pancreatic ductal adenocarcinoma, Oncology reports, vol.37, issue.2, p.27959420, 2017. ,
DOI : 10.3892/or.2016.5302
Identification of DEK as a potential therapeutic target for neuroendocrine prostate cancer, Oncotarget, vol.6, issue.3, p.4359333, 2015. ,
Overexpression of DEK gene is correlated with poor prognosis in hepatocellular carcinoma, Molecular medicine reports, vol.11, issue.2, p.25351213, 2015. ,
Critical role of DEK and its regulation in tumorigenesis and metastasis of hepatocellular carcinoma, Oncotarget, vol.7, issue.18, p.5042019, 2016. ,
Melanoma proliferation and chemoresistance controlled by the DEK oncogene, Cancer Res, vol.69, 2009. ,
DOI : 10.1158/0008-5472.can-09-1063
URL : http://cancerres.aacrjournals.org/content/canres/69/16/6405.full.pdf
DEK expression in melanocytic lesions, Human pathology, vol.42, issue.7, p.3162348, 2011. ,
DOI : 10.1016/j.humpath.2010.10.022
URL : http://europepmc.org/articles/pmc3162348?pdf=render
DEK promotes HPV-positive and-negative head and neck cancer cell proliferation, Oncogene, vol.34, issue.7, p.4160430, 2015. ,
DOI : 10.1038/onc.2014.15
URL : http://europepmc.org/articles/pmc4160430?pdf=render
DEK associates with tumor stage and outcome in HPV16 positive oropharyngeal squamous cell carcinoma, Oncotarget, vol.8, issue.14, p.28423581, 2017. ,
DOI : 10.18632/oncotarget.15582
URL : http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=15582&path%5B%5D=49774
The role of DEK protein in hepatocellular carcinoma for progression and prognosis, Pakistan journal of medical sciences, vol.29, issue.3, p.3809293, 2013. ,
DEK over expression as an independent biomarker for poor prognosis in colorectal cancer, BMC Cancer, vol.13, 2013. ,
DOI : 10.1186/1471-2407-13-366
URL : https://bmccancer.biomedcentral.com/track/pdf/10.1186/1471-2407-13-366?site=bmccancer.biomedcentral.com
DEK oncogene is overexpressed during melanoma progression. Pigment cell & melanoma research, p.27893188, 2016. ,
DOI : 10.1111/pcmr.12563
Esophageal Cancer: Genomic and Molecular Characterization, Stem Cell Compartment and Clonal Evolution. Medicines, vol.4, issue.3, 2017. ,
Global cancer statistics, CA Cancer J Clin, vol.61, issue.2, p.21296855, 2011. ,
Global cancer statistics, CA Cancer J Clin, vol.65, issue.2, p.25651787, 2012. ,
DOI : 10.3322/caac.21262
Etiology and chemoprevention of esophageal squamous cell carcinoma. Carcinogenesis, vol.22, 2001. ,
Comparable Molecular Alterations in 4-Nitroquinoline 1Oxide-induced Oral and Esophageal Cancer in Mice and in Human Esophageal Cancer, Associated with Poor Prognosis of Patients, vol.27, p.3849809, 2013. ,
Human papillomavirus tumor infection in esophageal squamous cell carcinoma, Journal of gastrointestinal oncology, vol.6, issue.3, p.4397257, 2015. ,
Treatment Outcomes of Patients with Locally Advanced Synchronous Esophageal and Head/Neck Squamous Cell Carcinoma Receiving Curative Concurrent Chemoradiotherapy, Scientific reports, vol.7, p.5278381, 2017. ,
DOI : 10.1038/srep41785
URL : http://www.nature.com/articles/srep41785.pdf
Identification of genomic alterations in oesophageal squamous cell cancer, Nature, vol.509, issue.7498, p.24670651, 2014. ,
DOI : 10.1038/nature13176
Genetic landscape of esophageal squamous cell carcinoma, Nature genetics, vol.46, issue.10, p.25151357, 2014. ,
Genomic and molecular characterization of esophageal squamous cell carcinoma, Nature genetics, vol.46, issue.5, p.4070589, 2014. ,
, Comprehensive genomic characterization of head and neck squamous cell carcinomas, Nature, vol.517, issue.7536, p.4311405, 2015.
Survivorship and Quality of Life in Head and Neck Cancer, J Clin Oncol, 2015. ,
The human DEK protooncogene is a senescence inhibitor and an upregulated target of high-risk human papillomavirus E7, Epub 2005/10/29, vol.79, p.1280217, 2005. ,
DEK protooncogene expression interferes with the normal epithelial differentiation program, Am J Pathol, vol.174, issue.1, p.2631320, 2009. ,
Apoptosis inhibition by the human DEK oncoprotein involves interference with p53 functions, Mol Cell Biol, vol.26, 2006. ,
Silencing of the DEK gene induces apoptosis and senescence in CaSki cervical carcinoma cells via the up-regulation of NF-kappaB p65, Bioscience reports, vol.32, issue.3, 2012. ,
Chromosomal imbalances are associated with a high risk of progression in early invasive (pT1) urinary bladder cancer, Cancer Res, vol.59, issue.22, pp.5687-91, 1999. ,
Detection of chromosomal imbalances in papillary bladder tumors by comparative genomic hybridization, Urology, vol.57, issue.5, pp.986-92, 2001. ,
Genomic signatures of chromosomal instability and osteosarcoma progression detected by high resolution array CGH and interphase FISH. Cytogenetic and genome research, vol.122, pp.5-15, 2008. ,
Delineation of the 6p22 amplification unit in urinary bladder carcinoma cell lines, Cancer Res, vol.60, issue.16, 2000. ,
Genomic amplification in retinoblastoma narrowed to 0.6 megabase on chromosome 6p containing a kinesin-like gene, RBKIN. Cancer Res, vol.62, issue.4, pp.967-71, 2002. ,
Functional pathways analyses to identify candidate therapeutic targets in triple-negative breast cancer, J Clin Oncol (Meeting Abstracts), vol.27, issue.15S, p.569, 2009. ,
FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation. The Journal of experimental medicine, vol.208, p.3039859, 2011. ,
The database of chromosome imbalance regions and genes resided in lung cancer from Asian and Caucasian identified by array-comparative genomic hybridization, BMC Cancer, vol.12, p.3488578, 2012. ,
MicroRNA-592 targets DEK oncogene and suppresses cell growth in the hepatocellular carcinoma cell line HepG2, International journal of clinical and experimental pathology, vol.8, issue.10, p.4680377, 2015. ,
Prostate cancer. Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer, Science, vol.346, issue.6205, p.25278611, 2014. ,
, , p.4257137
MiR-200a Suppresses the Proliferation and Metastasis in Pancreatic Ductal Adenocarcinoma through Downregulation of DEK Gene, Transl Oncol, vol.9, issue.1, p.4800058, 2016. ,
The DEK Oncogene Is a Target of Steroid Hormone Receptor Signaling in Breast Cancer, PloS one, vol.7, issue.10, p.23071688, 2012. ,
Promotion of cell proliferation by the proto-oncogene DEK enhances oral squamous cell carcinogenesis through field cancerization. Cancer medicine, p.28834425, 2017. ,
Oral cavity and esophageal carcinogenesis modeled in carcinogen-treated mice, Clin Cancer Res, vol.10, issue.1, pp.301-314, 2004. ,
Initiation of esophageal squamous cell carcinoma (ESCC) in a murine 4-nitroquinoline-1-oxide and alcohol carcinogenesis model, Oncotarget, vol.6, issue.8, p.25714027, 2015. ,
, , p.4467420
Chemical carcinogenesis models for evaluating molecular-targeted prevention and treatment of oral cancer. Cancer prevention research, vol.2, pp.419-441, 2009. ,
Persistence of high-grade cervical dysplasia and cervical cancer requires the continuous expression of the human papillomavirus type 16 E7 oncogene, Cancer Res, vol.69, issue.10, p.3006677, 2009. ,
The human DEK oncogene stimulates beta-catenin signaling, invasion and mammosphere formation in breast cancer, Oncogene, vol.30, issue.24, p.3117026, 2011. ,
Overexpression of the human DEK oncogene reprograms cellular metabolism and promotes glycolysis, PloS one, vol.12, issue.5, p.28558019, 2017. ,
DEK over-expression promotes mitotic defects and micronucleus formation, Cell Cycle, vol.14, issue.24, p.4825741, 2015. ,
DEK is a potential marker for aggressive phenotype and irinotecan-based therapy response in metastatic colorectal cancer, BMC Cancer, vol.14, p.4300837, 2014. ,
Oncoprotein DEK as a tissue and urinary biomarker for bladder cancer, BMC Cancer, vol.11, 2011. ,
Identification of two distinct progenitor populations in the lateral ganglionic eminence: implications for striatal and olfactory bulb neurogenesis. The Journal of neuroscience: the official journal of the Society for Neuroscience, vol.23, pp.167-74, 2003. ,
Human papillomavirus type 16 E6 and E7 oncoproteins act synergistically to cause head and neck cancer in mice, Virology, vol.407, issue.1, p.2946459, 2010. ,
Identification of biomarkers that distinguish human papillomavirus (HPV)-positive versus HPV-negative head and neck cancers in a mouse model, Proc Natl Acad Sci, vol.103, issue.38, p.1599927, 2006. ,
Parp-1 deficiency does not increase the frequency of tumors in the oral cavity and esophagus of ICR/129Sv mice by 4-nitroquinoline 1-oxide, a carcinogen producing bulky adducts, Cancer Lett, vol.241, issue.1, p.16338061, 2005. ,
DEK depletion negatively regulates Rho/ROCK/ MLC pathway in non-small cell lung cancer. The journal of histochemistry and cytochemistry: official journal of the Histochemistry Society, vol.61, 2013. ,
DOI : 10.1369/0022155413488120
URL : http://journals.sagepub.com/doi/pdf/10.1369/0022155413488120
A DEK domain-containing protein modulates chromatin structure and function in Arabidopsis. The Plant cell, vol.26, p.4277211, 2014. ,
DOI : 10.1105/tpc.114.129254
URL : http://www.plantcell.org/content/26/11/4328.full.pdf
Caspase-dependent apoptosis induction by targeted expression of DEK in Drosophila involves histone acetylation inhibition, Journal of cellular biochemistry, vol.103, issue.4, p.17685435, 2008. ,
DOI : 10.1002/jcb.21511
Image Processing with ImageJ, Biophotonics International, vol.11, issue.7, pp.36-42, 2004. ,
Conditional Gene Expression in the Epidermis of Transgenic Mice Using the Tetracycline-Regulated Transactivators tTA and rTA Linked to the Keratin 5 ,
, Journal of Investigative Dermatology, vol.115, issue.5, p.11069615
Defining the Epithelial Stem Cell Niche in Skin, Science, vol.303, issue.5656, p.2405920, 2004. ,
Isolation and Culture of Epithelial Stem Cells, Methods in molecular biology (Clifton, vol.482, p.2760227, 2009. ,
Isolation and Culture of Mouse Keratinocytes, Cold Spring Harbor Protocols, issue.7, 2008. ,