J. B. Ackman, L. Aniksztejn, V. Crepel, H. Becq, C. Pellegrino et al., Abnormal network activity in a targeted genetic model of human double cortex, J Neurosci, vol.29, pp.313-327, 2009.
URL : https://hal.archives-ouvertes.fr/inserm-00483164

R. Ako, M. Wakimoto, H. Ebisu, K. Tanno, R. Hira et al., Simultaneous visualization of multiple neuronal properties with single-cell resolution in the living rodent brain, Mol Cell Neurosci, vol.48, pp.246-257, 2011.

C. Auladell, A. Martinez, S. Alcantara, H. Super, and E. Soriano, Migrating neurons in the developing cerebral cortex of the mouse send callosal axons, Neuroscience, vol.64, pp.1091-1103, 1995.

S. T. Baek, G. Kerjan, S. L. Bielas, J. E. Lee, A. G. Fenstermaker et al., Off-target effect of doublecortin family shRNA on neuronal migration associated with endogenous microRNA dysregulation, Neuron, vol.82, pp.1255-1262, 2014.

N. Bahi-buisson, I. Souville, F. J. Fourniol, A. Toussaint, C. A. Moores et al., New insights into genotype-phenotype correlations for the doublecortin-related lissencephaly spectrum, Brain, vol.136, pp.223-244, 2013.

J. Bai, R. L. Ramos, J. B. Ackman, A. M. Thomas, R. V. Lee et al., RNAi reveals doublecortin is required for radial migration in rat neocortex, Nat Neurosci, vol.6, pp.1277-1283, 2003.

A. J. Barkovich, R. Guerrini, G. Battaglia, G. Kalifa, N. 'guyen et al., Band heterotopia: correlation of outcome with magnetic resonance imaging parameters, Ann Neurol, vol.36, pp.609-617, 1994.

S. Bechstedt and G. J. Brouhard, Doublecortin recognizes the 13protofilament microtubule cooperatively and tracks microtubule ends, Dev Cell, vol.23, pp.181-192, 2012.

K. P. Berry and E. Nedivi, Spine dynamics: are they all the same?, Neuron, vol.96, issue.1, pp.43-55, 2017.

S. L. Bielas, F. F. Serneo, M. Chechlacz, T. J. Deerinck, G. A. Perkins et al., Spinophilin facilitates dephosphorylation of doublecortin by PP1 to mediate microtubule bundling at the axonal wrist, Cell, vol.129, pp.579-591, 2007.

S. E. Bilasy, T. Satoh, S. Ueda, P. Wei, H. Kanemura et al., Dorsal telencephalon-specific RA-GEF-1 knockout mice develop heterotopic cortical mass and commissural fiber defect, Eur J Neurosci, vol.29, pp.1994-2008, 2009.

M. G. Blackmore, D. L. Moore, R. P. Smith, J. L. Goldberg, J. L. Bixby et al., High content screening of cortical neurons identifies novel regulators of axon growth, Mol Cell Neurosci, vol.44, pp.43-54, 2010.

J. Bouwman, A. S. Maia, P. G. Camoletto, G. Posthuma, E. W. Roubos et al., Quantification of synapse formation and maintenance in vivo in the absence of synaptic release, Neuroscience, vol.126, pp.115-126, 2004.

D. Cohen, M. Segal, and O. Reiner, Doublecortin supports the development of dendritic arbors in primary hippocampal neurons, Dev Neurosci, vol.30, pp.187-199, 2008.

E. Danielson and S. H. Lee, SynPAnal: software for rapid quantification of the density and intensity of protein puncta from fluorescence microscopy images of neurons, PLoS One, vol.9, p.115298, 2014.

C. Delandre, R. Amikura, and A. W. Moore, Microtubule nucleation and organization in dendrites, Cell Cycle, vol.15, pp.1685-1692, 2016.

E. W. Dent, Of microtubules and memory: implications for microtubule dynamics in dendrites and spines, Mol Biol Cell, vol.28, pp.1-8, 2017.

V. Des-portes, F. Francis, J. M. Pinard, I. Desguerre, M. L. Moutard et al., doublecortin is the major gene causing X-linked subcortical laminar heterotopia (SCLH), Hum Mol Genet, vol.7, pp.1063-1070, 1998.

R. S. Desikan and A. J. Barkovich, Malformations of cortical development, Ann Neurol, vol.80, pp.797-810, 2016.

D. Amato, C. J. Hicks, and S. P. , Development of the motor system: effects of radiation on developing corticospinal neurons and locomotor function, Exp Neurol, vol.70, pp.1-23, 1980.

A. Ebrahimi-gaillard, J. Guitet, C. Garnier, and M. Roger, Topographic distribution of efferent fibers originating from homotopic or heterotopic transplants: heterotopically transplanted neurons retain some of the developmental characteristics corresponding to their site of origin, Brain Res Dev Brain Res, vol.77, pp.271-283, 1994.

I. Ferrer, A. Xumetra, and J. Santamaria, Cerebral malformation induced by prenatal X-irradiation: an autoradiographic and Golgi study, J Anat, vol.138, pp.81-93, 1984.

F. Francis, A. Koulakoff, D. Boucher, P. Chafey, B. Schaar et al., Doublecortin is a developmentally regulated, microtubuleassociated protein expressed in migrating and differentiating neurons, Neuron, vol.23, pp.247-256, 1999.

G. Friocourt, A. Koulakoff, P. Chafey, D. Boucher, F. Fauchereau et al., Doublecortin functions at the extremities of growing neuronal processes, Cereb Cortex, vol.13, pp.620-626, 2003.

X. Fu, K. J. Brown, C. C. Yap, B. Winckler, J. K. Jaiswal et al., Doublecortin (Dcx) family proteins regulate filamentous actin structure in developing neurons, J Neurosci, vol.33, pp.709-721, 2013.

A. M. Garrett, D. Schreiner, M. A. Lobas, and J. A. Weiner, Gammaprotocadherins control cortical dendrite arborization by regulating the activity of a FAK/PKC/MARCKS signaling pathway, Neuron, vol.74, pp.269-276, 2012.

J. G. Gleeson, K. M. Allen, J. W. Fox, E. D. Lamperti, S. Berkovic et al., Doublecortin, a brain-specific gene mutated in human X-linked lissencephaly and double cortex syndrome, encodes a putative signaling protein, Cell, vol.92, pp.63-72, 1998.

M. A. Gonzalez-lozano, P. Klemmer, T. Gebuis, C. Hassan, P. Van-nierop et al., Dynamics of the mouse brain cortical synaptic proteome during postnatal brain development, Sci Rep, vol.6, p.35456, 2016.

J. Gu, B. L. Firestein, and J. Q. Zheng, Microtubules in dendritic spine development, J Neurosci, vol.28, pp.12120-12124, 2008.

R. Guerrini and W. B. Dobyns, Malformations of cortical development: clinical features and genetic causes, Lancet Neurol, vol.13, pp.710-726, 2014.

R. Guerrini and E. Parrini, Neuronal migration disorders, Neurobiol Dis, vol.38, pp.154-166, 2010.

Y. Hatanaka and F. Murakami, In vitro analysis of the origin, migratory behavior, and maturation of cortical pyramidal cells, J Comp Neurol, vol.454, pp.1-14, 2002.

D. Horesh, T. Sapir, F. Francis, S. G. Wolf, M. Caspi et al., Doublecortin, a stabilizer of microtubules, Hum Mol Genet, vol.8, pp.1599-1610, 1999.

X. Hu, C. Viesselmann, S. Nam, E. Merriam, and E. W. Dent, Activity-dependent dynamic microtubule invasion of dendritic spines, J Neurosci, vol.28, pp.13094-13105, 2008.

C. B. Jaeger and R. D. Lund, Transplantation of embryonic occipital cortex to the brain of newborn rats: a Golgi study of mature and developing transplants, J Comp Neurol, vol.200, pp.213-230, 1981.

J. Jaworski, L. C. Kapitein, S. M. Gouveia, B. R. Dortland, P. S. Wulf et al., Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity, Neuron, vol.61, pp.85-100, 2009.

K. F. Jensen and H. P. Killackey, Subcortical projections from ectopic neocortical neurons, Proc Natl Acad Sci U S A, vol.81, pp.964-968, 1984.

W. Joo, S. Hippenmeyer, and L. Luo, Dendrite morphogenesis depends on relative levels of NT-3/TrkC signaling, Science, vol.346, pp.626-629, 2014.

V. A. Kulkarni and B. L. Firestein, The dendritic tree and brain disorders, Mol Cell Neurosci, vol.50, pp.10-20, 2012.

K. S. Lee, F. Schottler, J. L. Collins, G. Lanzino, D. Couture et al., A genetic animal model of human neocortical heterotopia associated with seizures, J Neurosci, vol.17, pp.6236-6242, 1997.

Q. Lin, R. Ponnusamy, J. Widagdo, J. A. Choi, W. Ge et al., MicroRNA-mediated disruption of dendritogenesis during a critical period of development influences cognitive capacity later in life, Proc Natl Acad Sci U S A, vol.114, pp.9188-9193, 2017.

W. Lu, E. A. Bushong, T. P. Shih, M. H. Ellisman, and R. A. Nicoll, The cell-autonomous role of excitatory synaptic transmission in the regulation of neuronal structure and function, Neuron, vol.78, pp.433-439, 2013.

K. R. Maynard and E. Stein, DSCAM contributes to dendrite arborization and spine formation in the developing cerebral cortex, J Neurosci, vol.32, pp.16637-16650, 2012.

E. B. Merriam, D. C. Lumbard, C. Viesselmann, J. Ballweg, M. Stevenson et al., Dynamic microtubules promote synaptic NMDA receptor-dependent spine enlargement, PLoS One, vol.6, p.27688, 2011.

E. B. Merriam, M. Millette, D. C. Lumbard, W. Saengsawang, T. Fothergill et al., Synaptic regulation of microtubule dynamics in dendritic spines by calcium, F-actin, and drebrin, J Neurosci, vol.33, pp.16471-16482, 2013.

K. E. Moczulska, P. Pichler, M. Schutzbier, A. Schleiffer, S. Rumpel et al., Deep and precise quantification of the mouse synaptosomal proteome reveals substantial remodeling during postnatal maturation, J Proteome Res, vol.13, pp.4310-4324, 2014.

C. A. Moores, M. Perderiset, F. Francis, J. Chelly, A. Houdusse et al., Mechanism of microtubule stabilization by doublecortin, Mol Cell, vol.14, pp.833-839, 2004.

C. A. Moores, M. Perderiset, C. Kappeler, S. Kain, D. Drummond et al., Distinct roles of doublecortin modulating the microtubule cytoskeleton, EMBO J, vol.25, pp.4448-4457, 2006.

M. Moslehi, D. Ng, and M. A. Bogoyevitch, Dynamic microtubule association of Doublecortin X (DCX) is regulated by its C-terminus, Sci Rep, vol.7, p.5245, 2017.

S. C. Noctor, V. Martinez-cerdeno, L. Ivic, and A. R. Kriegstein, Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases, Nat Neurosci, vol.7, pp.136-144, 2004.

W. C. Oh, S. Lutzu, P. E. Castillo, and H. Kwon, De novo synaptogenesis induced by GABA in the developing mouse cortex, Science, vol.353, pp.1037-1040, 2016.

A. Pavlowsky, J. Chelly, and P. Billuart, Emerging major synaptic signaling pathways involved in intellectual disability, Mol Psychiatry, vol.17, pp.682-693, 2012.

L. F. Petit, M. Jalabert, E. Buhler, A. Malvache, A. Peret et al., Normotopic cortex is the major contributor to epilepsy in experimental double cortex, Ann Neurol, vol.76, pp.428-442, 2014.
URL : https://hal.archives-ouvertes.fr/inserm-01059741

F. Polleux, T. Morrow, and A. Ghosh, Semaphorin 3A is a chemoattractant for cortical apical dendrites, Nature, vol.404, pp.567-573, 2000.

R. L. Ramos, A. R. Toia, D. M. Pasternack, T. P. Dotzler, J. A. Cuoco et al., Neuroanatomical characterization of the cellular and axonal architecture of subcortical band heterotopia in the BXD29-Tlr4lps-2J/J mouse cortex, Neuroscience, vol.337, pp.48-65, 2016.

G. Sancini, S. Franceschetti, G. Battaglia, C. Colacitti, D. Luca et al., Dysplastic neocortex and subcortical heterotopias in methylazoxymethanol-treated rats: an intracellular study of identified pyramidal neurones, Neurosci Lett, vol.246, pp.181-185, 1998.

R. Sando, E. Bushong, Y. Zhu, M. Huang, C. Considine et al., Assembly of excitatory synapses in the absence of glutamatergic neurotransmission, Neuron, vol.94, pp.312-321, 2017.

I. U. Schapitz, B. Behrend, Y. Pechmann, C. Lappe-siefke, S. J. Kneussel et al., Neuroligin 1 is dynamically exchanged at postsynaptic sites, J Neurosci, vol.30, pp.12733-12744, 2010.

J. Schindelin, I. Arganda-carreras, E. Frise, V. Kaynig, M. Longair et al., Fiji: an open-source platform for biological-image analysis, Nat Methods, vol.9, pp.676-682, 2012.

M. L. Schwartz, P. Rakic, and P. S. Goldman-rakic, Early phenotype expression of cortical neurons: evidence that a subclass of migrating neurons have callosal axons, Proc Natl Acad Sci U S A, vol.88, pp.1354-1358, 1991.

R. Scorcioni, S. Polavaram, and G. A. Ascoli, L-Measure: a webaccessible tool for the analysis, comparison and search of digital reconstructions of neuronal morphologies, Nat Protoc, vol.3, pp.866-876, 2008.

A. Sigler, W. C. Oh, C. Imig, B. Altas, H. Kawabe et al., Formation and maintenance of functional spines in the absence of presynaptic glutamate release, Neuron, vol.94, pp.304-311, 2017.

M. Stiess and F. Bradke, Neuronal polarization: the cytoskeleton leads the way, Dev Neurobiol, vol.71, pp.430-444, 2011.

, Laminar Position and DCX Influence Synaptogenesis Martineau et al. | 2989

H. Tabata and K. Nakajima, Efficient in utero gene transfer system to the developing mouse brain using electroporation: visualization of neuronal migration in the developing cortex, Neuroscience, vol.103, pp.865-872, 2001.

T. Tanaka and J. G. Gleeson, Subcortical laminar (band) heterotopia, Handb Clin Neurol, vol.87, pp.191-204, 2008.
DOI : 10.1016/s0072-9752(07)87012-6

N. Tschuluun, J. H. Wenzel, K. Katleba, and P. A. Schwartzkroin, Initiation and spread of epileptiform discharges in the methylazoxymethanol acetate rat model of cortical dysplasia: functional and structural connectivity between CA1 heterotopia and hippocampus/neocortex, Neuroscience, vol.133, pp.327-342, 2005.

M. Tsukada, A. Prokscha, J. Oldekamp, and G. Eichele, Identification of neurabin II as a novel doublecortin interacting protein, Mech Dev, vol.120, pp.1033-1043, 2003.

M. Tsukada, A. Prokscha, E. Ungewickell, and G. Eichele, Doublecortin association with actin filaments is regulated by neurabin II, J Biol Chem, vol.280, pp.11361-11368, 2005.

P. Valnegri, S. V. Puram, and A. Bonni, Regulation of dendrite morphogenesis by extrinsic cues, Trends Neurosci, vol.38, pp.439-447, 2015.

F. Varoqueaux, A. Sigler, J. Rhee, N. Brose, C. Enk et al., Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming, Proc Natl Acad Sci U S A, vol.99, pp.9037-9042, 2002.

M. Verhage, A. S. Maia, J. J. Plomp, A. B. Brussaard, J. H. Heeroma et al., Synaptic assembly of the brain in the absence of neurotransmitter secretion, Science, vol.287, pp.864-869, 2000.

F. Watrin, J. B. Manent, C. Cardoso, and A. Represa, Causes and consequences of gray matter heterotopia, CNS Neurosci Ther, vol.21, pp.112-122, 2015.

R. Wong and A. Ghosh, Activity-dependent regulation of dendritic growth and patterning, Nat Rev Neurosci, vol.3, pp.803-812, 2002.

C. C. Yap, L. Digilio, L. Mcmahon, M. Roszkowska, C. J. Bott et al., Different Doublecortin (DCX) patient alleles show distinct phenotypes in cultured neurons: evidence for divergent loss-of-function and "off-pathway" cellular mechanisms, J Biol Chem, vol.291, pp.26613-26626, 2016.

S. Yoshihara, H. Takahashi, N. Nishimura, M. Kinoshita, R. Asahina et al., Npas4 regulates Mdm2 and thus Dcx in experience-dependent dendritic spine development of newborn olfactory bulb interneurons, Cell Rep, vol.8, pp.843-857, 2014.