Abstract : Classically, action potentials are initiated at the axon initial segment (AIS) when the summed depolarizing events arising from the dendrites exceed a threshold value. Then, action potentials propagate along the axon before reaching presynaptic
terminals where they cause local calcium influx and transmitter release. According to this scheme, the AIS is a major player since all propagated excitation is precisely initiated at this hot spot endowed with a high concentration of sodium channels.
https://hal-amu.archives-ouvertes.fr/hal-01963294
Contributor : Dominique Debanne <>
Submitted on : Friday, December 21, 2018 - 11:43:16 AM Last modification on : Wednesday, December 9, 2020 - 3:13:40 AM Long-term archiving on: : Friday, March 22, 2019 - 4:10:22 PM