Skip to Main content Skip to Navigation
Journal articles

Somatic modulation of ectopic action potential initiation in distal axons

Abstract : Classically, action potentials are initiated at the axon initial segment (AIS) when the summed depolarizing events arising from the dendrites exceed a threshold value. Then, action potentials propagate along the axon before reaching presynaptic terminals where they cause local calcium influx and transmitter release. According to this scheme, the AIS is a major player since all propagated excitation is precisely initiated at this hot spot endowed with a high concentration of sodium channels.
Complete list of metadatas

Cited literature [7 references]  Display  Hide  Download

https://hal-amu.archives-ouvertes.fr/hal-01963294
Contributor : Dominique Debanne <>
Submitted on : Friday, December 21, 2018 - 11:43:16 AM
Last modification on : Friday, April 17, 2020 - 2:56:03 PM
Long-term archiving on: : Friday, March 22, 2019 - 4:10:22 PM

Licence


Distributed under a Creative Commons Attribution 4.0 International License

Identifiers

Collections

Citation

Aurélie Fékété, Dominique Debanne. Somatic modulation of ectopic action potential initiation in distal axons. The Journal of Physiology, Wiley, 2018, 596 (21), pp.5067-5068. ⟨10.1113/jp277012⟩. ⟨hal-01963294⟩

Share

Metrics

Record views

83

Files downloads

278