Skip to Main content Skip to Navigation
Journal articles

Plasticity of intrinsic neuronal excitability

Abstract : Long-term synaptic modification is not the exclusive mode of memory storage, and persistent regulation of voltage-gated ion channels also participates in memory formation. Intrinsic plasticity is expressed in virtually all neuronal types including principal cells and interneurons. Activation of synaptic glutamate receptors initiates long-lasting changes in neuronal excitability at presynaptic and postsynaptic side. As synaptic plasticity, intrinsic plasticity is bi-directional and expresses a certain level of input-specificity or cell-specificity. We discuss here the nature of the learning rules shared by intrinsic and synaptic plasticity and the impact of intrinsic plasticity on temporal processing.
Complete list of metadatas

Cited literature [55 references]  Display  Hide  Download

https://hal-amu.archives-ouvertes.fr/hal-01963474
Contributor : Dominique Debanne <>
Submitted on : Friday, December 21, 2018 - 12:14:30 PM
Last modification on : Thursday, February 7, 2019 - 2:50:58 PM
Long-term archiving on: : Friday, March 22, 2019 - 3:19:17 PM

File

Debannne-Russier-2019.pdf
Publication funded by an institution

Licence


Distributed under a Creative Commons Attribution 4.0 International License

Identifiers

Collections

Citation

Dominique Debanne, Yanis Inglebert, Michaël Russier. Plasticity of intrinsic neuronal excitability. Current Opinion in Neurobiology, Elsevier, 2019, 54, pp.73-82. ⟨10.1016/j.conb.2018.09.001⟩. ⟨hal-01963474⟩

Share

Metrics

Record views

64

Files downloads

937