Skip to Main content Skip to Navigation
Journal articles

Cortical Auditory-Evoked Responses in Preterm Neonates: Revisited by Spectral and Temporal Analyses

Abstract : Characteristic preterm EEG patterns of "Delta-brushes" (DBs) have been reported in the temporal cortex following auditory stimuli, but their spatio-temporal dynamics remains elusive. Using 32-electrode EEG recordings and co-registration of electrodes' position to 3D-MRI of age-matched neonates, we explored the cortical auditory-evoked responses (AERs) after 'click' stimuli in 30 healthy neonates aged 30-38 post-menstrual weeks (PMW). (1) We visually identified auditory-evoked DBs within AERs in all the babies between 30 and 33 PMW and a decreasing response rate afterwards. (2) The AERs showed an increase in EEG power from delta to gamma frequency bands over the middle and posterior temporal regions with higher values in quiet sleep and on the right. (3) Time-frequency and averaging analyses showed that the delta component of DBs, which negatively peaked around 550 and 750 ms over the middle and posterior temporal regions, respectively, was superimposed with fast (alpha-gamma) oscillations and corresponded to the late part of the cortical auditory-evoked potential (CAEP), a feature missed when using classical CAEP processing. As evoked DBs rate and AERs delta to alpha frequency power decreased until full term, auditory-evoked DBs are thus associated with the prenatal development of auditory processing and may suggest an early emerging hemispheric specialization.
Document type :
Journal articles
Complete list of metadatas

Cited literature [110 references]  Display  Hide  Download

https://hal-amu.archives-ouvertes.fr/hal-01963801
Contributor : Fanny Pra <>
Submitted on : Friday, December 21, 2018 - 3:38:21 PM
Last modification on : Wednesday, August 19, 2020 - 11:18:37 AM
Long-term archiving on: : Friday, March 22, 2019 - 6:06:14 PM

File

Kaminska Cer Cor 2918.pdf
Publication funded by an institution

Licence


Distributed under a Creative Commons Attribution 4.0 International License

Identifiers

Collections

Citation

A. Kaminska, V Delattre, J Laschet, J Dubois, M Labidurie, et al.. Cortical Auditory-Evoked Responses in Preterm Neonates: Revisited by Spectral and Temporal Analyses. Cerebral Cortex, Oxford University Press (OUP), 2018, 28 (10), pp.3429-3444. ⟨10.1093/cercor/bhx206⟩. ⟨hal-01963801⟩

Share

Metrics

Record views

129

Files downloads

362