B. K. Andrásfalvy, M. A. Smith, T. Borchardt, R. Sprengel, and J. C. Magee, Impaired regulation of synaptic strength in hippocampal neurons from GluR1-deficient mice, J. Physiol, vol.552, pp.35-45, 2003.

D. M. Bannerman, R. M. Deacon, S. Brady, A. Bruce, R. Sprengel et al., A comparison of GluR-A-deficient and wild-type mice on a test battery assessing sensorimotor, affective, and cognitive behaviors, Behav. Neurosci, vol.118, pp.643-647, 2004.

T. V. Bliss and T. Lomo, Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path, J. Physiol, vol.232, pp.331-356, 1973.

A. Brechet, R. Buchert, J. Schwenk, S. Boudkkazi, G. Zolles et al., AMPA-receptor specific biogenesis complexes control synaptic transmission and intellectual ability, Nat. Commun, vol.8, p.15910, 2017.
URL : https://hal.archives-ouvertes.fr/hal-02044718

R. Brusa, F. Zimmermann, D. S. Koh, D. Feldmeyer, P. Gass et al., Early-onset epilepsy and postnatal lethality associated with an editing-deficient GluR-B allele in mice, Science, vol.270, pp.1677-1680, 1995.

N. Burnashev, H. Monyer, P. H. Seeburg, and B. Sakmann, Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit, Neuron, vol.8, pp.90120-90123, 1992.

R. M. Deacon and J. N. Rawlins, T-maze alternation in the rodent, Nat. Protoc, vol.1, pp.7-12, 2006.

E. C. Fuchs, A. R. Zivkovic, M. O. Cunningham, S. Middleton, F. E. Lebeau et al., Recruitment of parvalbumin-positive interneurons determines hippocampal function and associated behavior, Neuron, vol.53, pp.591-604, 2007.

R. Gerlai, J. T. Henderson, J. C. Roder, J. , and Z. , Multiple behavioral anomalies in GluR2 mutant mice exhibiting enhanced LTP, Behav. Brain Res, vol.95, pp.37-45, 1998.

A. J. Granger, Y. Shi, W. Lu, M. Cerpas, and R. A. Nicoll, LTP requires a reserve pool of glutamate receptors independent of subunit type, Nature, vol.493, pp.495-500, 2013.

I. H. Greger, L. Khatri, X. Kong, and E. B. Ziff, AMPA receptor tetramerization is mediated by Q/R editing, Neuron, vol.40, pp.763-774, 2003.

I. H. Greger, L. Khatri, and E. B. Ziff, RNA editing at arg607 controls AMPA receptor exit from the endoplasmic reticulum, Neuron, vol.34, pp.759-772, 2002.

M. Higuchi, S. Maas, F. N. Single, J. Hartner, A. Rozov et al., Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2, Nature, vol.406, pp.78-81, 2000.

D. A. Hoffman, R. Sprengel, and B. Sakmann, Molecular dissection of hippocampal theta-burst pairing potentiation, Proc. Natl. Acad. Sci. U S A, vol.99, pp.7740-7745, 2002.

V. Jensen, K. M. Kaiser, T. Borchardt, G. Adelmann, A. Rozov et al., A juvenile form of postsynaptic hippocampal long-term potentiation in mice deficient for the AMPA receptor subunit GluR-A, 2003.

, J. Physiol, vol.553, pp.843-856

Z. Jia, N. Agopyan, P. Miu, Z. Xiong, J. Henderson et al., , 1996.

, Enhanced LTP in mice deficient in the AMPA receptor GluR2, Neuron, vol.17, pp.945-956

K. Kask, D. Zamanillo, A. Rozov, N. Burnashev, R. Sprengel et al., The AMPA receptor subunit GluR-B in its Q/R site-unedited form is not essential for brain development and function, Proc. Natl. Acad. Sci. U S A, vol.95, pp.13777-13782, 1998.

K. Keinanen, W. Wisden, B. Sommer, P. Werner, A. Herb et al., A family of AMPA-selective glutamate receptors, Science, vol.249, pp.556-560, 1990.

J. Larson and G. Lynch, Induction of synaptic potentiation in hippocampus by patterned stimulation involves two events, Science, vol.232, pp.985-988, 1986.

W. Lu, Y. Shi, A. C. Jackson, K. Bjorgan, M. J. During et al., Subunit composition of synaptic AMPA receptors revealed by a single-cell genetic approach, Neuron, vol.62, pp.254-268, 2009.

N. V. Luchkina, S. K. Coleman, J. Huupponen, C. Cai, A. Kivistö et al., Molecular mechanisms controlling synaptic recruitment of GluA4 subunit-containing AMPA-receptors critical for functional maturation of CA1 glutamatergic synapses, Neuropharmacology, vol.112, pp.46-56, 2017.

M. Madeo, M. Stewart, Y. Sun, N. Sahir, S. Wiethoff et al., Loss-of-function mutations in FRRS1L lead to an epileptic-dyskinetic encephalopathy, Am. J. Hum. Genet, vol.98, pp.1249-1255, 2016.

H. Monyer, P. H. Seeburg, and W. Wisden, Glutamate-operated channels: developmentally early and mature forms arise by alternative splicing, Neuron, vol.6, pp.799-810, 1991.

R. G. Morris, Spatial localization does not require the presence of local cues, Learn. Motiv, vol.12, pp.239-260, 1981.

R. G. Morris, P. Garrud, J. N. Rawlins, and J. Keefe, Place navigation impaired in rats with hippocampal lesions, Nature, vol.297, pp.681-683, 1982.

A. Nagy, J. Rossant, R. Nagy, W. Abramow-newerly, and J. C. Roder, Derivation of completely cell culture-derived mice from earlypassage embryonic stem cells, Proc. Natl. Acad. Sci. U S A, vol.90, pp.8424-8428, 1993.

K. A. Pelkey, E. Barksdale, M. T. Craig, X. Yuan, M. Sukumaran et al., Pentraxins coordinate excitatory synapse maturation and circuit integration of parvalbumin interneurons, Neuron, vol.90, p.661, 2016.

K. Plant, K. A. Pelkey, Z. A. Bortolotto, D. Morita, A. Terashima et al., Transient incorporation of native GluR2-lacking AMPA receptors during hippocampal long-term potentiation, Nat. Neurosci, vol.9, pp.602-604, 2006.

D. Reisel, D. M. Bannerman, W. B. Schmitt, R. M. Deacon, J. Flint et al., Spatial memory dissociations in mice lacking GluR1, Nat. Neurosci, vol.5, pp.868-873, 2002.

C. Romberg, J. Raffel, L. Martin, R. Sprengel, P. H. Seeburg et al., Induction and expression of GluA1 (GluR-A)-independent LTP in the hippocampus, Eur. J. Neurosci, vol.29, pp.1141-1152, 2009.

A. Rozov, R. Sprengel, and P. H. Seeburg, GluA2-lacking AMPA receptors in hippocampal CA1 cell synapses: evidence from gene-targeted mice, Front. Mol. Neurosci, vol.5, p.22, 2012.

D. J. Sanderson, M. A. Good, K. Skelton, R. Sprengel, P. H. Seeburg et al., Enhanced long-term and impaired short-term spatial memory in GluA1 AMPA receptor subunit knockout mice: evidence for a dual-process memory model, Learn. Mem, vol.16, pp.379-386, 2009.

D. J. Sanderson, A. Gray, A. Simon, A. M. Taylor, R. M. Deacon et al., Deletion of glutamate receptor-A (GluR-A) AMPA receptor subunits impairs one-trial spatial memory, Behav. Neurosci, vol.121, pp.559-569, 2007.

D. J. Sanderson, E. Hindley, E. Smeaton, N. Denny, A. Taylor et al., Deletion of the GluA1 AMPA receptor subunit impairs recency-dependent object recognition memory, Learn. Mem, vol.18, pp.181-190, 2011.

D. J. Sanderson, R. Sprengel, P. H. Seeburg, and D. M. Bannerman, Deletion of the GluA1 AMPA receptor subunit alters the expression of short-term memory, Learn. Mem, vol.18, pp.128-131, 2011.

D. J. Sanderson, S. B. Mchugh, M. A. Good, R. Sprengel, P. H. Seeburg et al., Spatial working memory deficits in GluA1 AMPA receptor subunit knockout mice reflect impaired short-term habituation: evidence for Wagner's dual-process memory model, Neuropsychologia, vol.48, pp.2303-2315, 2010.

W. B. Schmitt, R. M. Deacon, P. H. Seeburg, J. N. Rawlins, and D. M. Bannerman, A within-subjects, within-task demonstration of intact spatial reference memory and impaired spatial working memory in glutamate receptor-A-deficient mice, J. Neurosci, vol.23, pp.3953-3959, 2003.

B. Sommer, M. Köhler, R. Sprengel, and P. H. Seeburg, RNA editing in brain controls a determinant of ion flow in glutamate-gated channels, Cell, vol.67, pp.11-19, 1991.

D. Soto, I. D. Coombs, L. Kelly, M. Farrant, and S. G. Candy, Stargazin attenuates intracellular polyamine block of calcium-permeable AMPA receptors, Nat Neurosci, vol.10, pp.1260-1267, 2007.

D. Soto, I. D. Coombs, M. Renzi, M. Zonouzi, M. Farrant et al., Selective regulation of long-form calcium-permeable AMPA receptors by an atypical TARP, ?-5, Nat. Neurosci, vol.12, pp.277-285, 2009.

R. Sprengel, R. Aronoff, M. Völkner, B. Schmitt, R. Mosbach et al., Glutamate receptor channel signatures, Trends Pharmacol. Sci, vol.22, pp.7-10, 2001.
DOI : 10.1016/s0165-6147(00)01588-1

G. T. Swanson, S. K. Kamboj, and S. G. Candy, Singlechannel properties of recombinant AMPA receptors depend on RNA editing, splice variation and subunit composition, J. Neurosci, vol.17, pp.58-69, 1997.

O. Y. Vekovischeva, T. Aitta-aho, O. Echenko, A. Kankaanpää, T. Seppälä et al., Reduced aggression in AMPA-type glutamate receptor GluR-A subunit-deficient mice, Genes Brain Behav, vol.3, pp.253-265, 2004.

O. Y. Vekovischeva, D. Zamanillo, O. Echenko, T. Seppälä, M. Uusi-oukari et al., Morphine-induced dependence and sensitization are altered in mice deficient in AMPA-type glutamate receptor-A subunits, J. Neurosci, vol.21, pp.4451-4459, 2001.

R. J. Wenthold, R. S. Petralia, J. I. Blahos, and A. S. Niedzielski, Evidence for multiple AMPA receptor complexes in hippocampal CA1/CA2 neurons, J. Neurosci, vol.16, 1982.

H. Wigström, G. , and B. , Facilitated induction of hippocampal long-lasting potentiation during blockade of inhibition, Nature, vol.301, pp.603-604, 1983.

H. Wigström, G. , and B. , Facilitation of hippocampal long-lasting potentiation by GABA antagonists, Acta Physiol. Scand, vol.125, pp.159-172, 1985.

D. Zamanillo, R. Sprengel, O. Hvalby, V. Jensen, N. Burnashev et al., Importance of AMPA receptors for hippocampal synaptic plasticity but not for spatial learning, Science, vol.284, pp.1805-1811, 1999.

J. J. Zhu, J. A. Esteban, Y. Hayashi, and R. Malinow, Postnatal synaptic potentiation: delivery of GluR4-containing AMPA receptors by spontaneous activity, Nat. Neurosci, vol.3, pp.1098-1106, 2000.

, Conflict of Interest Statement: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

. Copyright-©-;-bannerman, . Borchardt, . Jensen, . Rozov, . Haj-yasein et al., This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, 2018.