Meta-Analysis Reveals the Association Between Male Occupational Exposure to Solvents and Impairment of Semen Parameters
Abstract
Objectives: Solvent exposure is among the most common occupational exposures to chemical toxicants; data about the impact of such exposure on semen parameters are contradictory. We conducted the first meta-analysis to evaluate the risk of alteration in semen parameters related to occupational exposure to solvents.
Methods: From the PubMed database, we selected studies analyzing the semen of subjects occupationally exposed to solvents, compared with unexposed controls. The meta-analysis was performed on the various semen parameters analyzed in both populations.
Results: Seven studies were included in the study. The meta-analysis revealed a significant decrease in ejaculate volume [standardized mean difference (SMD) ¼ À0.35 (À0.63 to À0.07)] and sperm concentration [SMD ¼ À0.36 (À0.64 to À0.08)] in workers exposed to solvents compared with unexposed controls.
Conclusion: Our results highlight the importance of preventing reprotoxic risks to male fertility in the workplace.
Domains
Life Sciences [q-bio] Reproductive Biology Sexual reproduction Life Sciences [q-bio] Development Biology Gametogenesis Life Sciences [q-bio] Cancer Life Sciences [q-bio] Ecology, environment Health Life Sciences [q-bio] Toxicology Ecotoxicology Life Sciences [q-bio] Human health and pathology Gynecology and obstetrics Environmental Sciences Environmental and Society
Origin : Files produced by the author(s)
Loading...