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Synthesis of (±) cis-substituted cyclohexenyl and cyclohexanyl nucleosides via a double Mitsunobu-type reaction

Abstract : This letter describes the synthesis of (±) cis -substituted cyclohexenyl and cyclohexanyl nucleosides. The synthesis of cis isomers was successfully achieved by the use of two consecutive Mitsunobu reactions involving an inversion of configuration and a sugar–base condensation.
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https://hal-amu.archives-ouvertes.fr/hal-02061647
Contributor : Karine Barral Connect in order to contact the contributor
Submitted on : Friday, March 8, 2019 - 11:44:02 AM
Last modification on : Wednesday, December 8, 2021 - 3:33:49 AM

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Karine Barral, Philippe Halfon, Gérard Pèpe, Michel Camplo. Synthesis of (±) cis-substituted cyclohexenyl and cyclohexanyl nucleosides via a double Mitsunobu-type reaction. Tetrahedron Letters, Elsevier, 2002, 43 (1), pp.81-84. ⟨10.1016/S0040-4039(01)02107-4⟩. ⟨hal-02061647⟩

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