Journal articles
Synthesis and antiviral evaluation of 3-hydroxy-2-methylpyridin-4-one dideoxynucleoside derivatives
Abstract : We describe the synthesis and the antiviral evaluation of novel alpha and beta dideoxynucleoside derivatives in which the base has been replaced by a 3-hydroxy-2-methylpyridin-4-one. The syntheses were successfully achieved by the use of the standard Vorbrüggen coupling conditions. Moderate activity of these compounds were found on herpes simplex virus (HSV) type 1 and type 2.
https://hal-amu.archives-ouvertes.fr/hal-02061650
Contributor : karine barral Connect in order to contact the contributor
Submitted on : Friday, March 8, 2019 - 11:45:16 AM
Last modification on : Wednesday, December 8, 2021 - 3:33:49 AM
Contributor : karine barral Connect in order to contact the contributor
Submitted on : Friday, March 8, 2019 - 11:45:16 AM
Last modification on : Wednesday, December 8, 2021 - 3:33:49 AM
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