Assessment of Dengue virus helicase and methyltransferase as targets for fragment-based drug discovery

Bruno Coutard (1) , Etienne Decroly (1) , Changqing Li (1) , Andrew Sharff , Julien Lescar (2) , Gérard Bricogne (3) , Karine Barral (4)

1 AFMB - Architecture et fonction des macromolécules biologiques
2 CIMI - Centre d'Immunologie et de Maladies Infectieuses
3 Global Phasing
4 CRCM - Centre de Recherche en Cancérologie de Marseille

Domains: Chemical Sciences; Chemical Sciences; Medicinal Chemistry

Bruno Coutard, Etienne Decroly, Changqing Li, Andrew Sharff, Julien Lescar, et al.. Assessment of Dengue virus helicase and methyltransferase as targets for fragment-based drug discovery. Antiviral Research, 2014, 106, pp.61-70. ⟨10.1016/j.antiviral.2014.03.013⟩. ⟨hal-02061701⟩