Didehydro-Cortistatin A Inhibits HIV-1 by Specifically Binding to the Unstructured Basic Region of Tat

Sonia Mediouni (1) , Krishna Chinthalapudi (2) , Mary Ekka , Ippei Usui , Joseph Jablonski , Mark Clementz , Guillaume Mousseau (3) , Jason Nowak , Venkat Macherla , Jacob Beverage , Eduardo Esquenazi , Phil Baran , Ian Mitchelle S. de Vera , Douglas Kojetin , Erwann Loret (4) , Kendall Nettles , Souvik Maiti , Tina Izard (5) , Susana Valente , David Harrich , Vinayaka Prasad

1 AMU PHARM - Aix-Marseille Université - Faculté de pharmacie
2 Research Division for Structural Analysis, Hannover Medical School, OE8830, Carl-Neuberg-Strasse 1, D-30625 Hannover, Germany
3 IBITECS - Institut de Biologie et de Technologies de Saclay
4 IMBE - Institut méditerranéen de biodiversité et d'écologie marine et continentale
5 Department of Cancer Biology

Domains: Life Sciences [q-bio]; Life Sciences [q-bio]; Microbiology and Parasitology

Sonia Mediouni, Krishna Chinthalapudi, Mary Ekka, Ippei Usui, Joseph Jablonski, et al.. Didehydro-Cortistatin A Inhibits HIV-1 by Specifically Binding to the Unstructured Basic Region of Tat. ChemMedChem, 2019, 10 (1), ⟨10.1002/mbo3.530⟩. ⟨hal-02080280⟩