Recent synthesis of ellipticine and its derivatives

Malika Ibrahim-Ouali (1) , Frederic Dumur (2)

1 ISM2 - Institut des Sciences Moléculaires de Marseille
2 ICR - Institut de Chimie Radicalaire

The pyrido[4,3-b]carbazole alkaloid, ellipticine, was attracting considerable interest for many years due to its pronounced antitumor activity. We review the most important achievements in the field of ellipticine synthesis and its derivatives since 2012.

Mots clés: Ellipticine; ellipticine derivatives; alkaloids; synthesis

Domaines: Chimie organique; Chimie thérapeutique

Malika Ibrahim-Ouali, Frederic Dumur. Recent synthesis of ellipticine and its derivatives. ARKIVOC - Online Journal of Organic Chemistry, 2018, 2018 (1), pp.216-243. ⟨10.24820/ark.5550190.p010.445⟩. ⟨hal-02091469⟩