Synthesis of chiral 3-substituted 3-amino-2-oxindoles through enantioselective catalytic nucleophilic additions to isatin imines

Helene Pellissier (1)

1 ISM2 - Institut des Sciences Moléculaires de Marseille

This review collects the recent developments in the synthesis of chiral 3-substituted 3-amino-2-oxindoles based on enantioselective catalytic nucleophilic additions to isatin imines published since the beginning of 2015.

Mots clés: asymmetric synthesis; chiral 3-amino-2-oxindoles; chirality; isatin imines; nucleophilic addition

Domaines: Chimie organique; Catalyse

Helene Pellissier. Synthesis of chiral 3-substituted 3-amino-2-oxindoles through enantioselective catalytic nucleophilic additions to isatin imines. Beilstein Journal of Organic Chemistry, 2018, 14, pp.1349-1369. ⟨10.3762/bjoc.14.114⟩. ⟨hal-02091481⟩