Rapid synthesis of new 2-methyl-7-nitro-5-substituted-2,3-dihydroimidazo[5,1-b]oxazole as potential antibacterial drugs through one-pot cyclization and Suzuki-Miyaura coupling

Fanny Mathias; Maxime D. Crozet; Youssef Kabri; Patrice Vanelle

doi:10.1080/00397911.2018.1439177

Journal articles

Rapid synthesis of new 2-methyl-7-nitro-5-substituted-2,3-dihydroimidazo[5,1-b]oxazole as potential antibacterial drugs through one-pot cyclization and Suzuki-Miyaura coupling

Fanny Mathias ¹ Maxime D. Crozet ¹ Youssef Kabri ¹ Patrice Vanelle ¹

Abstract : Original 2-methyl-7-nitro-5-substituted-2,3-dihydroimidazo[5,1-b]oxazoles were prepared by reacting 1-(2,5-dibromo-4-nitro-1H-imidazol-1-yl)propan-2-ol and various arylboronic acids through one-pot cyclization and Suzuki-Miyaura reactions under microwave irradiation. [GRAPHICS] .

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Journal articles

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Chemical Sciences

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https://hal-amu.archives-ouvertes.fr/hal-02091930
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Submitted on : Saturday, April 6, 2019 - 5:18:49 PM
Last modification on : Sunday, April 7, 2019 - 1:22:52 AM

Rapid synthesis of new 2-methyl-7-nitro-5-substituted-2,3-dihydroimidazo[5,1-b]oxazole as potential antibacterial drugs through one-pot cyclization and Suzuki-Miyaura coupling

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Rapid synthesis of new 2-methyl-7-nitro-5-substituted-2,3-dihydroimidazo[5,1-b]oxazole as potential antibacterial drugs through one-pot cyclization and Suzuki-Miyaura coupling

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